Zobrazeno 1 - 10
of 16
pro vyhledávání: '"DMT1, divalent metal transporter 1"'
Publikováno v:
JACC: Basic to Translational Science
Highlights • Intravenous iron supplementation provides symptomatic relief in patients with heart failure and concomitant iron deficiency. • The current definition of iron deficiency based on ferritin
Summary To date, 3 clinical trials have s
Summary To date, 3 clinical trials have s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6416c88e304c21907d8eb5ffa905104a
https://doi.org/10.1016/j.jacbts.2019.08.009
https://doi.org/10.1016/j.jacbts.2019.08.009
Autor:
Nuria García-Magro, Cristina Fernández-Mendívil, Enrique Luengo, Paula Trigo-Alonso, Pilar Negredo, Manuela G. López
Publikováno v:
Redox Biology, Vol 38, Iss, Pp 101789-(2021)
Redox Biology
Redox Biology
Heme oxygenase-1 (HO-1) is an inducible enzyme known for its anti-inflammatory, antioxidant and neuroprotective effects. However, increased expression of HO-1 during aging and age-related neurodegenerative diseases have been associated to neurotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dfb34480f285e42eea2931b0cfeb92
http://www.sciencedirect.com/science/article/pii/S2213231720309940
http://www.sciencedirect.com/science/article/pii/S2213231720309940
Publikováno v:
The Journal of Biological Chemistry
The death of photoreceptor cells in dry age-related macular degeneration (AMD) and autosomal recessive Stargardt disease (STGD1) is closely associated with disruption in all-trans-retinal (atRAL) clearance in neural retina. In this study, we reveal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e528672cccb4554ebf9c4e807e79212a
https://pubmed.ncbi.nlm.nih.gov/33334878
https://pubmed.ncbi.nlm.nih.gov/33334878
Autor:
Ruth E. Carmichael, Laura DiGiovanni, Michael Schrader, Peter K. Kim, Rechal Kumar, Beatriz S.C. Silva
Publikováno v:
Biochim Biophys Acta Mol Cell Res
Biochimica et Biophysica Acta. Molecular Cell Research
Biochimica et Biophysica Acta. Molecular Cell Research
Membrane-bound organelles in eukaryotic cells form an interactive network to coordinate and facilitate cellular functions. The formation of close contacts, termed “membrane contact sites” (MCSs), represents an intriguing strategy for organelle in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9fe6acec67e4ef9fd0a3187b430591c
Publikováno v:
The Journal of Biological Chemistry
Birt-Hogg-Dubé (BHD) syndrome is a multiorgan disorder caused by inactivation of the folliculin (FLCN) protein. Previously, we identified FLCN as a binding protein of Rab11A, a key regulator of the endocytic recycling pathway. This finding implies t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34690bccc7c80fc336ddab9214444578
https://doi.org/10.1016/j.jbc.2021.100426
https://doi.org/10.1016/j.jbc.2021.100426
Autor:
Shunsuke Hatta, Satoshi Ichikawa, Yasushi Onishi, Urara Ota, Noriko Fukuhara, Yoko Okitsu, Masahiro Kobayashi, Hideo Harigae, Kei Saito, Tohru Fujiwara, Tohru Tanaka, Masahiro Ishizuka
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 105-111 (2017)
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 105-111 (2017)
5-Aminolevulinic acid (ALA) is a precursor for the biosynthesis of porphyrins and heme. Although the oral administration of ALA has been widely applied in clinical settings, the dynamics of its absorption, metabolism, and excretion within enterocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b82a9f47aca64455eb73801bac9a6a
https://pubmed.ncbi.nlm.nih.gov/28955775
https://pubmed.ncbi.nlm.nih.gov/28955775
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 563-569 (2014)
Redox Biology
Redox Biology
Curcumin has been shown to have many potentially health beneficial properties in vitro and in animal models with clinical studies on the toxicity of curcumin reporting no major side effects. However, curcumin may chelate dietary trace elements and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34111eb52cef8c02b7b58ec3fd7d6591
http://www.sciencedirect.com/science/article/pii/S2213231714000330
http://www.sciencedirect.com/science/article/pii/S2213231714000330
Autor:
Kostas Pantopoulos, Jian Wang
Publikováno v:
Biochemical Journal
Iron is an essential but potentially hazardous biometal. Mammalian cells require sufficient amounts of iron to satisfy metabolic needs or to accomplish specialized functions. Iron is delivered to tissues by circulating transferrin, a transporter that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa24e375048710c7f32509cbef225d5
http://europepmc.org/articles/PMC3048577
http://europepmc.org/articles/PMC3048577
Publikováno v:
Biochimica et Biophysica Acta
Astrocytes play a crucial role in proper iron handling within the central nervous system. This competence can be fundamental, particularly during neuroinflammation, and neurodegenerative processes, where an increase in iron content can favor oxidativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f309171fc42cfc627ec0e1e6119d4e
Autor:
Ghafourian K; Feinberg Cardiovascular and Renal Research Institute, Northwestern University, Chicago, Illinois., Shapiro JS; Feinberg Cardiovascular and Renal Research Institute, Northwestern University, Chicago, Illinois., Goodman L; Feinberg Cardiovascular and Renal Research Institute, Northwestern University, Chicago, Illinois., Ardehali H; Feinberg Cardiovascular and Renal Research Institute, Northwestern University, Chicago, Illinois.
Publikováno v:
JACC. Basic to translational science [JACC Basic Transl Sci] 2020 Mar 23; Vol. 5 (3), pp. 300-313. Date of Electronic Publication: 2020 Mar 23 (Print Publication: 2020).