Zobrazeno 1 - 10
of 16
pro vyhledávání: '"DMOG, dimethyloxalylglycine"'
Autor:
Kai Song, Cui Li, Xiangyun Li, Xinxin Hu, Zilei Xie, Haibo Li, Jia Shi, Shihan Du, Yuan Zhang, Si-meng He, Jianbo Yu, Shuan Dong, Tianxi Yu
Publikováno v:
Redox Biology
Redox Biology, Vol 41, Iss, Pp 101954-(2021)
Redox Biology, Vol 41, Iss, Pp 101954-(2021)
Increasing lines of evidence identified that dexmedetomidine (DEX) exerted protective effects against sepsis-stimulated acute lung injury via anti-inflammation, anti-oxidation and anti-apoptosis. However, the mechanisms remain unclear. Herein, we inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa1725ebff4e34b018ed458e6044f3d
http://europepmc.org/articles/PMC8027777
http://europepmc.org/articles/PMC8027777
Autor:
Dodd, MS, Sousa Fialho, MDL, Montes Aparicio, CN, Kerr, M, Timm, KN, Griffin, JL, Luiken, JJFP, Glatz, JFC, Tyler, DJ, Heather, LC
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • HIF-1α is activated following myocardial infarction, and is a critical transcription factor promoting survival in hypoxia. • Type 2 diabetes blunts HIF-1α activation in ischemia and downstream adaptation to hyp
Highlights • HIF-1α is activated following myocardial infarction, and is a critical transcription factor promoting survival in hypoxia. • Type 2 diabetes blunts HIF-1α activation in ischemia and downstream adaptation to hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5b03523fcf1d2ee305e6c87916135e75
http://europepmc.org/articles/PMC6115650
http://europepmc.org/articles/PMC6115650
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Hall, C H T, Campbell, E L & Colgan, S P 2017, ' Neutrophils as Components of Mucosal Homeostasis ', Cellular and Molecular Gastroenterology and Hepatology, vol. 4, no. 3, pp. 329-337 . https://doi.org/10.1016/j.jcmgh.2017.07.001
Hall, C H T, Campbell, E L & Colgan, S P 2017, ' Neutrophils as Components of Mucosal Homeostasis ', Cellular and Molecular Gastroenterology and Hepatology, vol. 4, no. 3, pp. 329-337 . https://doi.org/10.1016/j.jcmgh.2017.07.001
Inflammatory responses in the intestinal mucosa inevitably result in the recruitment of neutrophils (polymorphonuclear leukocytes [PMNs]). Epithelial cells that line the mucosa play an integral role in the recruitment, maintenance, and clearance of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c200733bc17426b28836c8bf6b2ea9
https://doi.org/10.1016/j.jcmgh.2017.07.001
https://doi.org/10.1016/j.jcmgh.2017.07.001
Autor:
Mario C. Manresa, Cormac T. Taylor
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 3, Pp 303-315 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Human health is dependent on the ability of the body to extract nutrients, fluids, and oxygen from the external environment while at the same time maintaining a state of internal sterility. Therefore, the cell layers that cover the surface areas of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078970de01ba053ce78cb200a21c695e
https://doi.org/10.1016/j.jcmgh.2017.02.004
https://doi.org/10.1016/j.jcmgh.2017.02.004
Publikováno v:
Redox Biology
Redox Biology, Vol 12, Iss, Pp 403-409 (2017)
Redox Biology, Vol 12, Iss, Pp 403-409 (2017)
Cancer cells have an altered redox status, with changes in intracellular signaling pathways. The knowledge of how such processes are regulated in 3D spheroids, being well-established tumor models, is limited. To approach this question we stably trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f4d61526fa1062febdeb9131e25dab39
http://europepmc.org/articles/PMC5357678
http://europepmc.org/articles/PMC5357678
Publikováno v:
The Journal of Biological Chemistry
Cathepsin H (CTSH) is a type 1 diabetes (T1D) risk gene; large-scale genetic and epidemiological studies found that T1D genetic risk correlates with high CTSH expression, rapid decline of beta-cell function, and early onset T1D. Counterintuitively, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eae34e14d7e500ffbcf2d3bf74cbc54
https://doi.org/10.1016/j.jbc.2021.100774
https://doi.org/10.1016/j.jbc.2021.100774
Autor:
William Yuan, Marcia C. Haigis, Alison E. Ringel, Samantha J. Wong, Joao A. Paulo, Haejin Yoon, Mark A. Currie
Publikováno v:
The Journal of Biological Chemistry
Since the discovery of the prolyl hydroxylases domain (PHD) proteins and their canonical hypoxia-inducible factor (HIF) substrate two decades ago, a number of in vitro hydroxylation (IVH) assays for PHD activity have been developed to measure the PHD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fbf41f03fef736ff3ca54873213228
https://doi.org/10.1016/j.jbc.2021.100397
https://doi.org/10.1016/j.jbc.2021.100397
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 32, Iss 6 (2012)
BIOSCIENCE REPORTS
Bioscience Reports, Vol 32, Iss 6 (2012)
BIOSCIENCE REPORTS
Mitochondrial uncoupling is implicated in many patho(physiological) states. Using confocal live cell imaging and an optical O2 sensing technique, we show that moderate uncoupling of the mitochondria with plecomacrolide Baf (bafilomycin A1) causes par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b572061200d79278790790cf8ab28758
https://doi.org/10.1042/bsr20120085
https://doi.org/10.1042/bsr20120085
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