Výsledky vyhledávání - "DMEM, Dulbecco׳s modified Eagle׳s medium"

Hypocrellin A-based photodynamic action induces apoptosis in A549 cells through ROS-mediated mitochondrial signaling pathway

Autor: Shu-Qin Yu, Shuang-Lin Chen, Ling-Yuan Guo, Robert J. Lee, Shan-Shan Qi, Shu-Zhen Yan

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 279-293 (2019)

Over recent decades, many studies have reported that hypocrellin A (HA) can eliminate cancer cells with proper irradiation in several cancer cell lines. However, the precise molecular mechanism underlying its anticancer effect has not been fully defi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234a255e7495bc3248845012723dbc6e
https://doi.org/10.1016/j.apsb.2018.12.004

Zobrazit plný text záznamu

Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity

Autor: Can, Hu, Xin, Zhang, Wenying, Wei, Ning, Zhang, Haiming, Wu, Zhenguo, Ma, Lingli, Li, Wei, Deng, Qizhu, Tang

Publikováno v: Acta Pharmaceutica Sinica. B

Oxidative stress and cardiomyocyte apoptosis are involved in the pathogenesis of doxorubicin (DOX)-induced cardiotoxicity. Matrine is well-known for its powerful anti-oxidant and anti-apoptotic capacities. Our present study aimed to investigate the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::015f20723028430fc57693619c6e943f
https://pubmed.ncbi.nlm.nih.gov/31384530

Zobrazit plný text záznamu

High-throughput screening for small molecule inhibitors of the type-I interferon signaling pathway

Autor: Dehua Yang, Ming-Wei Wang, Peter J Crack, Elita Yuliantie, Dai Xinchuan

Publikováno v: Acta Pharmaceutica Sinica B, Vol 8, Iss 6, Pp 889-899 (2018)
Acta Pharmaceutica Sinica. B

Interferons (IFNs) are cytokines with fundamental roles in resistance to infections, cancer and other diseases. Type-I IFNs, interferon α (IFN-α) and interferon β (IFN-β), act through a shared receptor complex (IFNAR) comprised of IFNAR1 and IFNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab71055575e2eeff424ad482248a8d45
https://pubmed.ncbi.nlm.nih.gov/30505658

Zobrazit plný text záznamu

Olmutinib (HM61713) reversed multidrug resistance by inhibiting the activity of ATP-binding cassette subfamily G member 2

Autor: Zhiqiang, Zhang, Xiaoran, Guo, Kenneth K W, To, Zhen, Chen, Xiaona, Fang, Min, Luo, Chunling, Ma, Jianhua, Xu, Shirong, Yan, Liwu, Fu

Publikováno v: Acta Pharmaceutica Sinica. B

Overexpressing of ATP-binding cassette (ABC) transporters is the essential cause of multidrug resistance (MDR), which is a significant hurdle to the success of chemotherapy in many cancers. Therefore, inhibiting the activity of ABC transporters may b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55c56cc9b202781bd5b272f8d90ee3e2
https://pubmed.ncbi.nlm.nih.gov/30109181

Zobrazit plný text záznamu

Fucoidan protects hepatocytes from apoptosis and inhibits invasion of hepatocellular carcinoma by up-regulating p42/44 MAPK-dependent NDRG-1/CAP43

Autor: Chung Yong Kim, Yoon Jun Kim, Jung Hwan Yoon, Su Jong Yu, Jeong Hoon Lee, Minjong Lee, Yuri Cho, Jeong-Ju Yoo, Dong Hyeon Lee, Eun Ju Cho

Publikováno v: Acta Pharmaceutica Sinica B, Vol 5, Iss 6, Pp 544-553 (2015)
Acta Pharmaceutica Sinica. B

Fucoidan is a traditional Chinese medicine suggested to possess anti-tumor effects. In this study the anti-metastatic effects of fucoidan were investigated in vitro in human hepatocellular carcinoma (HCC) cells (Huh-7 and SNU-761) under normoxic and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1b87af69d8fa9246f89bc5aef0e562
http://www.sciencedirect.com/science/article/pii/S2211383515001367

Zobrazit plný text záznamu

Anti-influenza virus activity of the ethanolic extract from Peperomia sui

Autor: Ting-Ting Jong, Chih-Hsueh Yang, Wei-Li Hsu, Chi-Luan Wen, Shih-Lan Hsu, Poa-Chun Chang, Duen-Huey Tan

Publikováno v: Journal of Ethnopharmacology

Ethnopharmacological relevance Peperomia sui Lin and Lu (Peperomia sui), a well-known Taiwanese folk medicine, has a broad range of biological effects, especially in treatment of upper respiratory tract diseases. However, no previous study has explor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b36c82d6a1c10344987fc2353e5fd5
https://doi.org/10.1016/j.jep.2014.05.035

Zobrazit plný text záznamu

Akademický článek

Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPK α /UCP2 pathway.

Autor: Hu C; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China., Zhang X; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China., Wei W; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China., Zhang N; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China., Wu H; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China., Ma Z; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China., Li L; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China., Deng W; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China., Tang Q; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China.; Hubei Key Laboratory of Cardiology, Wuhan 430060, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2019 Jul; Vol. 9 (4), pp. 690-701. Date of Electronic Publication: 2019 Mar 16.

Zobrazit plný text záznamu

Akademický článek

Aurone derivatives as Vps34 inhibitors that modulate autophagy.

Autor: Li G; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China., Boyle JW; School of Chemistry, Monash University, Clayton 3800, Australia., Ko CN; Department of Chemistry, Hong Kong Baptist University, Hong Kong 999077, China., Zeng W; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China., Wong VKW; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China., Wan JB; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China., Chan PWH; School of Chemistry, Monash University, Clayton 3800, Australia.; Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK., Ma DL; Department of Chemistry, Hong Kong Baptist University, Hong Kong 999077, China., Leung CH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2019 May; Vol. 9 (3), pp. 537-544. Date of Electronic Publication: 2019 Jan 30.

Zobrazit plný text záznamu

Akademický článek

Targeting slug-mediated non-canonical activation of c-Met to overcome chemo-resistance in metastatic ovarian cancer cells.

Autor: Chang L; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Hu Y; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Fu Y; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Zhou T; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., You J; Zhejiang Cancer Hospital, Hangzhou 310022, China., Du J; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Zheng L; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Cao J; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Ying M; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Dai X; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Su D; Zhejiang Cancer Hospital, Hangzhou 310022, China., He Q; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Zhu H; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Yang B; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2019 May; Vol. 9 (3), pp. 484-495. Date of Electronic Publication: 2019 Mar 02.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání