Zobrazeno 1 - 10
of 288
pro vyhledávání: '"DM Geddes"'
Autor:
PI Shah, A Bush, GJ Canny, AA Colin, HJ Fuchs, DM Geddes, CA Johnson, MC Light, SF Scott, DE Tullis, al. et
Publikováno v:
European Respiratory Journal. 8:954-958
Chronic pulmonary infection is the major cause of morbidity and mortality in cystic fibrosis (CF). Recombinant human deoxyribonuclease (rhDNase) in vitro has been shown to dramatically reduce the viscoelasticity of the sputum from CF patients. Phase
Autor:
Andrew Wardlaw, Dm, Geddes
Publikováno v:
Europe PubMed Central
Autor:
HM Earl, RM Rudd, SG Spiro, CM Ash, LE James, CS Law, JS Tobias, PG Harper, DM Geddes, D Eraut, MR Partridge, RL Souhami
Publikováno v:
British Journal of Cancer
In a study of chemotherapy as palliative treatment, 300 patients with untreated limited and extensive stage small cell lung cancer (SCLC), who did not have progressive disease after the first cycle of chemotherapy, were randomised to receive either r
Publikováno v:
European Respiratory Journal. 4:5-9
Measurement of the potential difference (PD) across the airways provides an indication of the viability and integrity of the lining epithelium. PD was recorded from the lower airways in "diseased controls" and in patients following heart-lung transpl
Publikováno v:
The European respiratory journal. 6(9)
In cystic fibrosis (CF) airway epithelial sodium absorption is increased 2-3 fold. Since sodium absorption is inhibited by the sodium channel blocker amiloride, our aim was to assess its therapeutic benefit in cystic fibrosis. A randomized, double-bl
Publikováno v:
The European respiratory journal. 3(8)
Patients with cystic fibrosis (CF) demonstrate a markedly more negative potential difference (PD) across respiratory epithelia than normal or "diseased" controls. A technique is described for the measurement of nasal PD in both children and adults. 1
Autor:
SL Chadwick, HD Kingston, M Stern, RM Cook, BJ O’Connor, M Lukasson, RP Balfour, M Rosenberg, SH Cheng, AE Smith, DP Meeker, DM Geddes, E W F W Alton
Publikováno v:
Gene Therapy. 5:569-569
Publikováno v:
European Respiratory Journal. 2:285-288
Shwachman's Syndrome is a rare disorder which causes considerable morbidity in childhood and can be confused with cystic fibrosis. Six patients (4 males; mean age 27 yrs) are described in order to illustrate the clinical picture of the syndrome in ad
Publikováno v:
Facts, views & vision in ObGyn [Facts Views Vis Obgyn] 2021 Dec; Vol. 13 (4), pp. 395-398.
Autor:
Alton EWFW; Imperial College London, London, UK. Electronic address: e.alton@imperial.ac.uk., Armstrong DK; Royal Hospital for Sick Children, Edinburgh, UK., Ashby D; Imperial College London, London, UK., Bayfield KJ; Imperial College London, London, UK., Bilton D; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Bloomfield EV; Imperial College London, London, UK., Boyd AC; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Brand J; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Buchan R; Western General Hospital, Edinburgh, UK., Calcedo R; Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA., Carvelli P; Imperial College London, London, UK., Chan M; Imperial College London, London, UK., Cheng SH; Genzyme, a Sanofi Company, Framingham, MA, USA., Collie DDS; The Roslin Institute and R(D)SVS, University of Edinburgh, Edinburgh, UK., Cunningham S; Royal Hospital for Sick Children, Edinburgh, UK., Davidson HE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Davies G; Imperial College London, London, UK., Davies JC; Imperial College London, London, UK., Davies LA; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Dewar MH; Western General Hospital, Edinburgh, UK., Doherty A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Donovan J; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Dwyer NS; Imperial College London, London, UK., Elgmati HI; Western General Hospital, Edinburgh, UK., Featherstone RF; Imperial College London, London, UK., Gavino J; Imperial College London, London, UK., Gea-Sorli S; Imperial College London, London, UK., Geddes DM; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Gibson JSR; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Gill DR; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Greening AP; Western General Hospital, Edinburgh, UK., Griesenbach U; Imperial College London, London, UK., Hansell DM; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Harman K; Imperial College London, London, UK., Higgins TE; Imperial College London, London, UK., Hodges SL; Imperial College London, London, UK., Hyde SC; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hyndman L; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Innes JA; Western General Hospital, Edinburgh, UK., Jacob J; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Jones N; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Keogh BF; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Limberis MP; Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lloyd-Evans P; NHS Blood and Transplant, Bristol, UK., Maclean AW; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Manvell MC; Imperial College London, London, UK., McCormick D; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., McGovern M; Western General Hospital, Edinburgh, UK., McLachlan G; The Roslin Institute and R(D)SVS, University of Edinburgh, Edinburgh, UK., Meng C; Imperial College London, London, UK., Montero MA; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Milligan H; Western General Hospital, Edinburgh, UK., Moyce LJ; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Murray GD; Usher Institute of Population Health Sciences and Informatics and Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Nicholson AG; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Osadolor T; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Parra-Leiton J; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Pringle IA; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Punch EK; Imperial College London, London, UK., Pytel KM; Imperial College London, London, UK., Quittner AL; University of Miami, Miami, FL, USA., Rivellini G; Imperial College London, London, UK., Saunders CJ; Imperial College London, London, UK., Scheule RK; Genzyme, a Sanofi Company, Framingham, MA, USA., Sheard S; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Simmonds NJ; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Smith K; NHS Blood and Transplant, Bristol, UK., Smith SN; Imperial College London, London, UK., Soussi N; Imperial College London, London, UK., Soussi S; Imperial College London, London, UK., Spearing EJ; Imperial College London, London, UK., Stevenson BJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Sumner-Jones SG; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Turkkila M; Imperial College London, London, UK., Ureta RP; Imperial College London, London, UK., Waller MD; Imperial College London, London, UK., Wasowicz MY; Imperial College London, London, UK., Wilson JM; Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA., Wolstenholme-Hogg P; Genzyme, a Sanofi Company, Framingham, MA, USA.
Publikováno v:
The Lancet. Respiratory medicine [Lancet Respir Med] 2015 Sep; Vol. 3 (9), pp. 684-691. Date of Electronic Publication: 2015 Jul 03.