A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells

Autor: Daniel M. Trindade, Kathleen W. Kinnally, F O Nascimento Júnior, Antonio Carlos Borges, Enilza Maria Espreáfico, J F Sousa, Ana Paiva, Pablo M. Peixoto, D P S Leitão Mazzi, Cleidson de Pádua Alves, T C Izidoro-Toledo, E V Patussi, Daniela Dover de Araújo

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cell Death & Disease

Previous studies proposed that myosin-Va regulates apoptosis by sequestering pro-apoptotic Bmf to the actin cytoskeleton through dynein light chain-2 (DLC2). Adhesion loss or other cytoskeletal perturbations would unleash Bmf, allowing it to bind and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cfeaf8d98072c3c1ff8e06e65a7eda