Zobrazeno 1 - 10
of 324
pro vyhledávání: '"DJ Veale"'
Autor:
Anna O'Rourke, Matthew A. Turk, Lorraine O'Neill, S. Quinn, Ursula Fearon, Anne-Barbara Mongey, DJ Veale, Kieran Murray, E. Molloy
Publikováno v:
Annals of the Rheumatic Diseases. 80:891.2-892
Background:SARS-CoV2 has caused over two million deaths globally. The relationship between rheumatic and musculoskeletal disease (RMDs), immunosuppressive medications and COVID-19 is unclear.Objectives:This study explores the rates of COVID-19 sympto
Autor:
D. Deely, S. Foo, Ursula Fearon, S Ansboro, E.J. MacDermott, Ronan H Mullan, DJ Veale, A. O’ Brien, Achilleas Floudas, Charlene Foley, S. Wade, O. Killeen
Publikováno v:
Annals of the Rheumatic Diseases. 80:241.1-241
Background:Juvenile idiopathic arthritis (JIA) was thought to be the most common inflammatory arthritis in children (Shih et al., 2019). However an aggressive, erosive arthritis of little-known immunologic mechanism occurs 20 times more frequently in
Publikováno v:
Abstracts.
Career situation of first and presenting author Post-doctoral fellow. Introduction Myeloid cells with a monocyte/macrophages phenotype are present in large numbers in the rheumatoid arthritis (RA) joint, significantly contributing to disease. Objecti
Publikováno v:
Abstracts.
Autor:
Ursula Fearon, Candice Low, Mary Canavan, Viviana Marzaioli, S. Wade, DJ Veale, Achilleas Floudas
Publikováno v:
Abstracts.
Background Tofacinitib (Pfizer) is an oral Janus kinase inhibitor, recently approved for the treatment of rheumatoid arthritis (RA). Although its mechanism of action has been explored in circulating cells, in particular neutrophils and lymphocyte, it
Autor:
Mary Canavan, Breandán N. Kennedy, DJ Veale, Ursula Fearon, Trudy McGarry, H McLaouglin, N Ohnesorge, Sarah M. Wade, M Biniecka
Publikováno v:
Abstracts.
Career situation of first and presenting author Post-doctoral fellow. Introduction Psoriatic arthritis (PsA) is characterised by an early vascular phase essential for pannus growth, immune responses and disease progression. Recently, numerous studies
Autor:
Ursula Fearon, Benjamin Ory, Frédéric Blanchard, P. Preuss, Steven Georges, B. Le Goff, DJ Veale, Thibaut Quillard, F. M. Masson, Aurélie Najm
Publikováno v:
Annals of the Rheumatic Diseases. 79:252.2-253
Background:micro-RNAs (miR) are strong regulators of gene expression. Their involvement in RA key cytokines pathway regulation entitles them as important players in RA pathophysiology. The miR 17-92 cluster has been widely studied in cancer as they r
Autor:
Lorraine O'Neill, Conor Murphy, Ursula Fearon, DJ Veale, Geraldine M. McCarthy, P. Gallagher, E. Molloy, Richard Conway
Publikováno v:
Saturday, 16 JUNE 2018.
Background Giant cell arteritis (GCA) is the most common form of systemic vasculitis; the pathogenesis is unclear. Current evidence suggests both the TH1 and TH17 pathways are important but the proximal initiators and effector cytokines are unknown.
Publikováno v:
Saturday, 16 JUNE 2018.
Background Diversity of macrophage subsets within the joint remains unknown. The concept of macrophage polarisation into M1 inflammatory macrophages and M2 tissue-resolving macrophages, parelled by changes in the bioenergetic cell profile, has receiv
Publikováno v:
Saturday, 16 JUNE 2018.
Background Synovial biopsies are increasingly performed in both clinical setting and translational research.1 An unmet need in the field is the standardisation of synovial biopsies handling and analysis procedures. Objectives The aim of this collabor