Zobrazeno 1 - 10
of 97
pro vyhledávání: '"DITA, M. A."'
Publikováno v:
Indonesian Journal of Clinical Pharmacy. 11:145-154
Metabolic syndrome is still a major problem in developing countries and it has an association with high blood pressure, blood glucose, and lipid profile abnormalities, which can cause cardiovascular disease. This indicates that it is important to pro
Autor:
Ramadevi Prathapam, Alexandra Frommlet, Jacob Shaul, Dita M. Rasper, Xiaoyu Shen, Alexey Ruzin, Sharadha Subramanian, Feng Wang, Micah Steffek, Bret Benton, Jason Vo, Steven Shia, Wooseok Han, Andreas O. Frank, Charles Wartchow, Patrick Lee, Xiaolei Ma, Fergal Casey, Hanne Merritt, Carl J. Balibar, Alun Bermingham, Elizabeth Ornelas, Tsuyoshi Uehara, Andreas Lingel, Chi-Min Ho, Barbara Chie-Leon, William S. Sawyer, Min-Kyu Cho, Sylvia Ma, Katherine R Prosen, Min Li, Christopher M. Rath, Gianfranco De Pascale
Publikováno v:
Journal of the American Chemical Society. 142:4445-4455
The lipopolysaccharide biosynthesis pathway is considered an attractive drug target against the rising threat of multi-drug-resistant Gram-negative bacteria. Here, we report two novel small-molecule inhibitors (compounds 1 and 2) of the acyltransfera
Publikováno v:
Acta Medica Indonesiana, Vol 47, Iss 4 (2015)
Aim: to evaluate the participant rate of the new universal health coverage (UHC) and its impact on the hypertensive subjects from the rural area in the Sleman-District of Yogyakarta during the early implementation. Methods: this epidemiological surve
Externí odkaz:
https://doaj.org/article/8b59bd651ee54e259901eb37fea1ab29
Autor:
Harkaneri, Firman Sujatmiko, Rahmawati Ramli, Maria Assumpta, Dika F. Anjarwati, Muhammad Yusran, Lusiana Kanji, Mustakim Muchlis, Binti S. Jannah, Wa O. Rayyani, Ahmad Kudhori, Ratna A. Aripratiwi, Syahrul Djafar, Ria A. Sholihah, Luky Patricia, Eka Siskawati, Abdul Mun'im, Adib A. Nizar, Ahmad F. Fathoni, A'isyah M. Sholihah, Wijaya, Dita M. Agustina, Virginia N. Rahmanti, Dani Sugiri, Rian Vebrianto, Ayudia Sokarina, A A Gde Satia Utama, Erika Takidah, Selvia E. Aristantia, Dwi I.F. Wijaya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a9b9a8081ceca8f2f8dccdc6a3a96a
https://doi.org/10.52893/peneleh.2020.24.ags.dkk
https://doi.org/10.52893/peneleh.2020.24.ags.dkk
Autor:
Xiaoyu Shen, William S. Sawyer, Micah Steffek, Wooseok Han, Tsuyoshi Uehara, Andreas O. Frank, Sharadha Subramanian, Alexey Ruzin, Feng Wang, Alexandra Frommlet, C. M. Baxter Rath, Hanne Merritt, Min Li, Alun Bermingham, Elizabeth Ornelas, Jason Vo, Fergal Casey, B. Chie-Leon, Andreas Lingel, Bret Benton, Xiaolei Ma, Steven Shia, Carl J. Balibar, G. de Pascale, Jacob Shaul, Patrick Lee, Dita M. Rasper, Min-Kyu Cho, Charles Wartchow, Sylvia Ma, Chi-Min Ho, Katherine R Prosen, Ramadevi Prathapam
The lipopolysaccharide biosynthesis pathway is considered an attractive drug target against the rising threat of multidrug-resistant Gram-negative bacteria. Here, we report two novel small-molecule inhibitors (compounds 1 and 2) of the acyltransferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2ae79f01d04aaef1188b455cc539e9
Autor:
Cindy Li, Xu Zang, Vijay Sethuraman, Xiaoyu Shen, Johanne Blais, Heinz E. Moser, Kyuto Tashiro, Ellie Growcott, Ramadevi Prathapam, Anthony Casarez, Aregahegn Yifru, Charles Vitt, David McKenney, Tsuyoshi Uehara, Patrick J Rudewicz, Fengxia Li, Hongqiu Guo, Adriana K. Jones, Louis E. Metzger, Wanben Gong, Jacob Shaul, Alun Bermingham, Taryn Cariaga, Richard Colvin, Xiaodong Lin, Dita M. Rasper, Mika Lindvall, Dazhi Tang, Vladimir Capka, Steven Whitebread, Sara Lopez, Meiliana Tjandra, Qingming Zhu, Nancy Turner, Robert Lowell Simmons, Charles R. Dean, Alex Fekete, Folkert Reck
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:748-755
Metallo-β-lactamases (MBLs), such as New Delhi metallo-β-lactamase (NDM-1) have spread world-wide and present a serious threat. Expression of MBLs confers resistance in Gram-negative bacteria to all classes of β-lactam antibiotics, with the except
Autor:
Srijan Ranjitkar, Xian Zhang, Robert Lowell Simmons, William J. Godinez, Imtiaz Hossain, Helen Chan, Brian Y. Feng, Cindy Li, Dita M. Rasper
Publikováno v:
ACS chemical biology. 14(6)
Beta-lactams comprise one of the earliest classes of antibiotic therapies. These molecules covalently inhibit enzymes from the family of penicillin-binding proteins (PBPs), which are essential in construction of the bacterial cell wall. As a result,
Autor:
Sandro Nocito, Anthony Casarez, Sara Lopez, Cindy Li, Louis E. Metzger, Johanne Blais, Kyuto Tashiro, Charles R. Dean, Kaci Phizackerley, Alun Bermingham, Dazhi Tang, Folkert Reck, Jacob Shaul, Richard Colvin, Markus Furegati, Dita M. Rasper, Robert Lowell Simmons, Luis Gamboa, Qin Yue, Xiaoyu Shen, Ellena Growcott, Flavio Ossola
Publikováno v:
ACS infectious diseases. 5(7)
Resistance in Gram-negative bacteria to β-lactam drugs is mediated primarily by the expression of β-lactamases, and co-dosing of β-lactams with a β-lactamase inhibitor (BLI) is a clinically proven strategy to address resistance. New β-lactamases
Autor:
Robert Lowell Simmons, Helen Chan, William J. Godinez, Dita M. Rasper, Imtiaz Hossain, Srijan Ranjitkar, Cindy Li, Brian Y. Feng, Xian Zhang
Beta-lactam antibiotics comprise one of the earliest known classes of antibiotic therapies. These molsecules covalently inhibit enzymes from the family of penicillin-binding proteins, which are essential to the construction of the bacterial cell wall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952e9b250d8acb775ccf88cd1be69e06
https://doi.org/10.1101/545335
https://doi.org/10.1101/545335
Autor:
Richard Colvin, Dita M. Rasper, Johanne Blais, Adriana K. Jones, Ramadevi Prathapam, Alexey Ruzin, Xiaoyu Shen, John Fuller, Anthony Casarez, Jun-Rong Wei, Sara Lopez, Alun Bermingham, Peter Skewes-Cox, Tsuyoshi Uehara, Pramila Tamrakar, David T. Barkan, Fergal Casey, Louis E. Metzger, Mina Mostafavi, Robert Lowell Simmons, Kenneth T. Takeoka, Charles R. Dean, Folkert Reck, Cindy Li, Jacob Shaul
The monobactam scaffold is attractive for the development of new agents to treat infections caused by drug-resistant Gram-negative bacteria because it is stable to metallo-β-lactamases (MBLs). However, the clinically used monobactam aztreonam lacks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b6aef2e61e0d9a42ba314a881df917
https://europepmc.org/articles/PMC6153799/
https://europepmc.org/articles/PMC6153799/