Zobrazeno 1 - 10
of 16 634
pro vyhledávání: '"DIRECTED EVOLUTION"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Formate dehydrogenase (FDH) is widely applied in regeneration of redox cofactors. There are continuing interests to engineer FDH for improved catalytic activity and cofactor preference. In the crystal structure of FDH from Pseudomonas sp. 10
Externí odkaz:
https://doaj.org/article/eaf2b6db501a4ec49b3424656facff51
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Improving crop traits requires genetic diversity, which allows breeders to select advantageous alleles of key genes. In species or loci that lack sufficient genetic diversity, synthetic directed evolution (SDE) can supplement natural variation, thus
Externí odkaz:
https://doaj.org/article/5f2a600c2b944db286321e1bfdfb5756
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 7691-7708 (2024)
Xun Zhou,1,2,* Jingzhou Liu,2,* Shuang Xiao,2,3,* Xiaoqing Liang,1,2 Yi Li,2 Fengzhen Mo,3 Xin Xin,2 Yang Yang,2 Chunsheng Gao1,2 1School of Pharmacy, Henan University, Kaifeng, People’s Republic of China; 2State Key Laboratory of Toxic
Externí odkaz:
https://doaj.org/article/58c2fe22206644798bb3b5c759c63da4
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Adeno-associated viruses 2 (AAV2) are minute viruses renowned for their capacity to infect human cells and akin organisms. They have recently emerged as prominent candidates in the field of gene therapy, primarily attributed to their inheren
Externí odkaz:
https://doaj.org/article/553499d5eb064011adeae295355f32b3
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/97fe3e1f166c4ff087e53066ca0428cf
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Inefficient conversion of small molecule maltooligosaccharides into trehalose greatly affects the cost of the production of trehalose by double enzyme method [maltooligosyl trehalose synthase (MTSase) and maltooligosyl trehalose trehalohyrolase (MTHa
Externí odkaz:
https://doaj.org/article/5f5b8bae82c14a9ba6b0beeab2911fdc
Publikováno v:
Frontiers in Catalysis, Vol 4 (2024)
In the past 20 years, unspecific peroxygenases (UPOs) have emerged as promising biocatalysts for various organic transformations. Particularly, we have witnessed great attention being paid to the screening of new enzymes and expansion of the substrat
Externí odkaz:
https://doaj.org/article/5dc8d277b2a14b6fa0b7e7465b718a21
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Directed evolution is a powerful tool that can bypass gaps in our understanding of the sequence-function relationship of proteins and still isolate variants with desired activities, properties, and substrate specificities. The rise of directed evolut
Externí odkaz:
https://doaj.org/article/c1bc1e805d0a446b9d89e7f53b9ac9c8
Autor:
Yao‐An Yu, Wan‐Ju Lien, Wen‐Ching Lin, Yi‐Chung Pan, Sin‐Wei Huang, Chung‐Yuan Mou, Che‐Ming Jack Hu, Kurt Yun Mou
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract The development of immune cell engagers (ICEs) can be limited by logistical and functional restrictions associated with fusion protein designs, thus limiting immune cell recruitment to solid tumors. Herein, a high affinity superantigen‐bas
Externí odkaz:
https://doaj.org/article/268a26cde0e142bcba3823b5f3520a6e