Zobrazeno 1 - 10
of 212
pro vyhledávání: '"DIPANKAR BHATTACHARYA"'
Autor:
Kavita Prasad, Dipankar Bhattacharya, Shams Gamal Eldin Shams, Kimberly Izarraras, Tia Hart, Brent Mayfield, Maryjka B. Blaszczyk, Zhongren Zhou, Utpal B. Pajvani, Scott L. Friedman, Moshmi Bhattacharya
Publikováno v:
Cells, Vol 13, Iss 19, p 1651 (2024)
The peptide hormone kisspeptin attenuates liver steatosis, metabolic dysfunction-associated steatohepatitis (MASH), and fibrosis in mouse models by signaling via the kisspeptin 1 receptor (KISS1R). However, whether kisspeptin impacts fibrogenesis in
Externí odkaz:
https://doaj.org/article/f6bf918860db4020a0e795793a52110f
Autor:
Marie O’Farrell, Greg Duke, Richard Crowley, Douglas Buckley, Eduardo B. Martins, Dipankar Bhattacharya, Scott L. Friedman, George Kemble
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Fatty acid synthase (FASN) is an attractive therapeutic target in non-alcoholic steatohepatitis (NASH) because it drives de novo lipogenesis and mediates pro-inflammatory and fibrogenic signaling. We therefore tested pharmacological inhibiti
Externí odkaz:
https://doaj.org/article/b33eeb880fcb45fca9716afc443aa3b3
Publikováno v:
The Astrophysical Journal, Vol 976, Iss 1, p 123 (2024)
GW150914 marked the start of the gravitational wave (GW) era with the direct detection of a binary black hole (BBH) merger by the LIGO-Virgo GW detectors. The event was tentatively associated with a signal detected by the Fermi Gamma-ray Burst Monito
Externí odkaz:
https://doaj.org/article/bfe93fe2147f401c8099815528bd3969
Autor:
Swadesh Chand, Gulab C. Dewangan, Andrzej A. Zdziarski, Dipankar Bhattacharya, N. P. S. Mithun, Santosh V. Vadawale
Publikováno v:
The Astrophysical Journal, Vol 972, Iss 1, p 20 (2024)
We perform broadband (0.7–100 keV) spectral analysis of five hard state observations of the low-mass black hole X-ray binary GX 339–4 taken by AstroSat during the rising phase of three outbursts from 2019 to 2022. We find that the outburst in 202
Externí odkaz:
https://doaj.org/article/17ae9cb4ecc645fb90ae84e1597f1aa1
Publikováno v:
The Astrophysical Journal, Vol 967, Iss 2, p 129 (2024)
We report simultaneous detection of twin kHz and ∼40 Hz quasiperiodic oscillations (QPOs) in the time-resolved analysis of the AstroSat/LAXPC observation of the neutron star low-mass X-ray binary, 4U 1728-34. The frequencies of the multiple sets of
Externí odkaz:
https://doaj.org/article/f3d6c91096964767af0826fb88b18ea8
Autor:
Srimanta Banerjee, Gulab C. Dewangan, Christian Knigge, Maria Georganti, Poshak Gandhi, N. P. S. Mithun, Payaswini Saikia, Dipankar Bhattacharya, David M. Russell, Fraser Lewis, Andrzej A. Zdziarski
Publikováno v:
The Astrophysical Journal, Vol 964, Iss 2, p 189 (2024)
We present a comprehensive multiwavelength spectral analysis of the black hole (BH) X-ray binary MAXI J1820+070 during its 2018 outburst, utilizing AstroSat far-UV, soft X-ray, and hard X-ray data, along with (quasi-)simultaneous optical and X-ray da
Externí odkaz:
https://doaj.org/article/92dfc355b4fc486aa80a0959da6de84c
Autor:
Tanmoy Chattopadhyay, Abhay Kumar, A. R. Rao, Yash Bhargava, Santosh V. Vadawale, Ajay Ratheesh, Gulab Dewangan, Dipankar Bhattacharya, N. P. S. Mithun, Varun Bhalerao
Publikováno v:
The Astrophysical Journal Letters, Vol 960, Iss 1, p L2 (2023)
Cygnus X-1, the well-known accreting black hole system, exhibits several observational features hinting at an intricate interplay between the accretion disk, its atmosphere known as the corona, and the putative relativistic jet. It has been extensive
Externí odkaz:
https://doaj.org/article/b4a8ba7ae09b41fcbe9a8319ed345fee
Autor:
Dipankar Bhattacharya, Christine Becker, Benjamin Readhead, Nicolas Goossens, Jacqueline Novik, Maria Isabel Fiel, Leslie P. Cousens, Björn Magnusson, Anna Backmark, Ryan Hicks, Joel T. Dudley, Scott L. Friedman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Non-alcoholic steatohepatitis (NASH) is a rising health challenge, with no approved drugs. We used a computational drug repositioning strategy to uncover a novel therapy for NASH, identifying a GABA-B receptor agonist, AZD3355 (Lesogaberan)
Externí odkaz:
https://doaj.org/article/b83db01028b94994911b0442d41b0959
Autor:
Dipankar Bhattacharya, Brittany Basta, Jose M. Mato, Amanda Craig, David Fernández-Ramos, Fernando Lopitz-Otsoa, Darya Tsvirkun, Liat Hayardeny, Vasuretha Chandar, Robert E. Schwartz, Augusto Villanueva, Scott L. Friedman
Publikováno v:
JHEP Reports, Vol 3, Iss 3, Pp 100237- (2021)
Summary: Background & Aims: Aramchol is a fatty acid-bile acid conjugate that reduces liver fat content and is being evaluated in a phase III clinical trial for non-alcoholic steatohepatitis (NASH). Aramchol attenuates NASH in mouse models and decrea
Externí odkaz:
https://doaj.org/article/07ba8fe24ed7447a841dc9fde349a0da
Autor:
James K Carter, Dipankar Bhattacharya, Joshua N Borgerding, M Isabel Fiel, Jeremiah J Faith, Scott L Friedman
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244763 (2021)
Background & aimNon-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD) that is responsible for a growing fraction of cirrhosis and liver cancer cases worldwide. Changes in the gut microbiome have been impli
Externí odkaz:
https://doaj.org/article/60b207e17bac473783c80497954c0aa0