Zobrazeno 1 - 10
of 223
pro vyhledávání: '"DIANA COSTA"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 961 (2024)
The lack of effective delivery systems has slowed the development of mitochondrial gene therapy. Delivery systems based on cell-penetrating peptides (CPPs) like the WRAP (tryptophan and arginine-rich peptide) family conjugated with a mitochondrial ta
Externí odkaz:
https://doaj.org/article/8fd7aea4000942cab91b968d53696caf
Autor:
Ana Neves, Tânia Albuquerque, Rúben Faria, Cecília R. A. Santos, Eric Vivès, Prisca Boisguérin, Diana Carneiro, Daniel F. Bruno, Maria D. Pavlaki, Susana Loureiro, Ângela Sousa, Diana Costa
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 781 (2024)
Glioblastoma multiform (GBM) is considered the deadliest brain cancer. Conventional therapies are followed by poor patient survival outcomes, so novel and more efficacious therapeutic strategies are imperative to tackle this scourge. Gene therapy has
Externí odkaz:
https://doaj.org/article/02e018d7653d4ab49535cb4f87628511
Autor:
Vitória Naomi Yabiku Toyama, Michele Andrade de Barros, Andréa Barros Piazzon de Souza Queiroz, Diana Costa Nascimento
Publikováno v:
Pubvet, Vol 16, Iss 5, Pp 1-16 (2022)
O presente trabalho traz uma revisão de literatura relacionada aos principais aspectos da lipidose hepática em aves adultas da espécie Amazona aestiva, conhecida como papagaio-verdadeiro ou papagaio-de-fronte-azul, cada vez mais popular como anima
Externí odkaz:
https://doaj.org/article/66d848d6e4c54415937ded2f3fa0d7bf
Autor:
Rafael Mineiro, Tânia Albuquerque, Ana Raquel Neves, Cecília R. A. Santos, Diana Costa, Telma Quintela
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12541 (2023)
For brain protection, the blood–brain barrier and blood–cerebrospinal fluid barrier limit the traffic of molecules between blood and brain tissue and between blood and cerebrospinal fluid, respectively. Besides their protective function, brain ba
Externí odkaz:
https://doaj.org/article/93886c68a069498cac28d87b9156978c
Autor:
Tânia Albuquerque, Ana Raquel Neves, Milan Paul, Swati Biswas, Elena Vuelta, Ignacio García-Tuñón, Manuel Sánchez-Martin, Telma Quintela, Diana Costa
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 7, p 362 (2023)
The circadian clock controls behavior and physiology. Presently, there is clear evidence of a connection between this timing system and cancer development/progression. Moreover, circadian rhythm consideration in the therapeutic action of anticancer d
Externí odkaz:
https://doaj.org/article/f1614c48910e4ee1af46c4be82818902
Autor:
Mariana Amaral, Nuno Cruz, Ana Rosa, Beatriz Nogueira, Diana Costa, Francisco Santos, Mariana Brazão, Pedro Policarpo, Rita Mateus, Yan Kobozev, Catarina Pinto Reis
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 20, Pp 1544-1570 (2021)
Glioblastoma multiforme (GBM) is a very aggressive and heterogeneous glioma. Currently, GBM is treated with a combination of surgery, radiotherapy, chemotherapy (e.g. temozolamide) and Tumour Treating Fields. Unfortunately, the mean survival is sti
Externí odkaz:
https://doaj.org/article/0ddc4a83778f46f594cdc3d8cc71491d
Publikováno v:
E3, Vol 9, Iss 1 (2022)
A crise pandémica da COVID-19 transformou profundamente a forma como vivemos as nossas vidas e o modo como as organizações trabalham. O sector empresarial precisou de compreender qual seria a melhor abordagem para continuar a sua atividade, pelo q
Externí odkaz:
https://doaj.org/article/da0e20baaaa9416796fca387f9a92254
Autor:
Camila Dias, Teresa Sousa, Aniana Cruz, Diana Costa, João Castelhano, Gabriel Pires, Miguel Castelo-Branco
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 264-265 (2023)
Externí odkaz:
https://doaj.org/article/545cb5cf06374b03a235b7226325f5f3
Autor:
João Estiveira, Camila Dias, Diana Costa, João Castelhano, Miguel Castelo-Branco, Teresa Sousa
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
Error-related electroencephalographic (EEG) signals have been widely studied concerning the human cognitive capability of differentiating between erroneous and correct actions. Midfrontal error-related negativity (ERN) and theta band oscillations are
Externí odkaz:
https://doaj.org/article/5e004bc0984a4019a5195b7fc13b86d4
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 936 (2023)
Quercetin is a natural flavonoid with high anticancer activity, especially for related-HPV cancers such as cervical cancer. However, quercetin exhibits a reduced aqueous solubility and stability, resulting in a low bioavailability that limits its the
Externí odkaz:
https://doaj.org/article/3e9b67b91f0f4b579c80f543193e7748