Zobrazeno 1 - 10
of 36
pro vyhledávání: '"DIA, Data Independent Acquisition"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4228-4237 (2023)
Metaproteomics has increasingly been applied to study functional changes in the human gut microbiome. Peptide identification is an important step in metaproteomics research, with sequence database search (SDS) and spectral library search (SLS) as the
Externí odkaz:
https://doaj.org/article/5f18163573f046c98476f2cee08c0dc0
Akademický článek
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Akademický článek
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Autor:
Sasha Mendjan, Gabriela Krššáková, Claudia Ctortecka, Johannes Stadlmann, Karel Stejskal, Josef M. Penninger, Karl Mechtler
Publikováno v:
Mol Cell Proteomics
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Single-cell transcriptomics has revolutionized our understanding of basic biology and disease. Since transcript levels often do not correlate with protein expression, it is crucial to complement transcriptomics approaches with proteome analyses at si
Publikováno v:
Molecular & Cellular Proteomics : MCP
Drug resistance is a critical obstacle to effective treatment in patients with chronic myeloid leukemia. To understand the underlying resistance mechanisms in response to imatinib mesylate (IMA) and adriamycin (ADR), the parental K562 cells were trea
Autor:
Nikolai Slavov
Publikováno v:
Molecular & Cellular Proteomics : MCP
Single-cell tandem MS has enabled analyzing hundreds of single cells per day and quantifying thousands of proteins across the cells. The broad dissemination of these capabilities can empower the dissection of pathophysiological mechanisms in heteroge
Autor:
van Bentum, Mirjam, Selbach, Matthias
Publikováno v:
Molecular & Cellular Proteomics : MCP
Targeted proteomics via selected reaction monitoring (SRM) or parallel reaction monitoring (PRM) enables fast and sensitive detection of a preselected set of target peptides. However, the number of peptides that can be monitored in conventional targe
Publikováno v:
Molecular & Cellular Proteomics : MCP
Recent advances in efficiency and ease of implementation have rekindled interest in ion mobility spectrometry, a technique that separates gas phase ions by their size and shape and that can be hybridized with conventional LC and MS. Here, we review t
Autor:
Karl J. Wahlin, Jun Wan, Ravi Chakra Turaga, Cynthia A. Berlinicke, Jiang Qian, Joseph L. Mertz, Melissa M. Liu, Ming-Wen Hu, Donald J. Zack, Srinivasa R. Sripathi, Julien Maruotti
Publikováno v:
Molecular & Cellular Proteomics : MCP
Stress and injury to the retinal pigment epithelium (RPE) often lead to dedifferentiation and epithelial-to-mesenchymal transition (EMT). These processes have been implicated in several retinal diseases, including proliferative vitreoretinopathy, dia
Autor:
Xiaomin Lou, Yang Fan, Fenli Zhou, Guixue Hou, Yanxia Liu, Fei Chen, Jin Zi, Yan Ren, Qingchuan Zhao, Siqi Liu, Bin Bai, Yuting Liang
Publikováno v:
Molecular & Cellular Proteomics : MCP
Signet ring cell carcinoma (SRCC) is a histological subtype of gastric cancer with distinct features in multiple aspects compared with adenocarcinomas (ACs). The lack of a systematic molecular overview of this disease has led to slow progress in its