KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors

Autor: Di Fiore, A., Bellardinelli, S., Pirone, L., Russo, R., Angrisani, A., Terriaca, G., Bowen, M., Bordin, F., Besharat, Z.M., Canettieri, G., Fabretti, F., Di Gaetano, S., Di Marcotullio, L., Pedone, E., Moretti, M., De Smaele, E.

Publikováno v: In Neoplasia September 2023 43

A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 β-like: from in silico identification to experimental evidence

Autor: Bosso, A., Pirone, L., Gaglione, R., Pane, K., Del Gatto, A., Zaccaro, L., Di Gaetano, S., Diana, D., Fattorusso, R., Pedone, E., Cafaro, V., Haagsman, H.P., van Dijk, A., Scheenstra, M.R., Zanfardino, A., Crescenzi, O., Arciello, A., Varcamonti, M., Veldhuizen, E.J.A., Di Donato, A., Notomista, E., Pizzo, E.

Publikováno v: In BBA - General Subjects September 2017 1861(9):2342-2353

Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS.

Autor: Diana D; CNR - Institute of Biostructures and Bioimaging Via Pietro Castellino 111 80131 Naples Italy emilia.pedone@cnr.it., Pirone L; CNR - Institute of Biostructures and Bioimaging Via Pietro Castellino 111 80131 Naples Italy emilia.pedone@cnr.it., Russo L; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies - University of Campania 'Luigi Vanvitelli' Via Vivaldi 43 81100 Caserta Italy gaetano.malgieri@unicampania.it roberto.fattorusso@unicampania.it., D'Abrosca G; Department of Clinical and Experimental Medicine - University of Foggia Viale Luigi Pinto 71122 Foggia Italy., Madheswaran M; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies - University of Campania 'Luigi Vanvitelli' Via Vivaldi 43 81100 Caserta Italy gaetano.malgieri@unicampania.it roberto.fattorusso@unicampania.it., Benfante R; Department of Medical Biotechnology and Translational Medicine (BIOMETRA), Università degli Studi di Milano Milan Italy.; CNR - Institute of Neuroscience Vedano Al Lambro (MB) Italy.; NeuroMi - Milan Center for Neuroscience, University of Milano Bicocca Milan Italy., Di Lascio S; Department of Medical Biotechnology and Translational Medicine (BIOMETRA), Università degli Studi di Milano Milan Italy., Caldinelli L; Department of Biotechnology and Life Sciences, University of Insubria Via J.H. Dunant 3 21100 Varese Italy., Fornasari D; Department of Medical Biotechnology and Translational Medicine (BIOMETRA), Università degli Studi di Milano Milan Italy., Acconcia C; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies - University of Campania 'Luigi Vanvitelli' Via Vivaldi 43 81100 Caserta Italy gaetano.malgieri@unicampania.it roberto.fattorusso@unicampania.it., Corvino A; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies - University of Campania 'Luigi Vanvitelli' Via Vivaldi 43 81100 Caserta Italy gaetano.malgieri@unicampania.it roberto.fattorusso@unicampania.it., Ventserova N; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies - University of Campania 'Luigi Vanvitelli' Via Vivaldi 43 81100 Caserta Italy gaetano.malgieri@unicampania.it roberto.fattorusso@unicampania.it., Pollegioni L; Department of Biotechnology and Life Sciences, University of Insubria Via J.H. Dunant 3 21100 Varese Italy., Isernia C; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies - University of Campania 'Luigi Vanvitelli' Via Vivaldi 43 81100 Caserta Italy gaetano.malgieri@unicampania.it roberto.fattorusso@unicampania.it., Di Gaetano S; CNR - Institute of Biostructures and Bioimaging Via Pietro Castellino 111 80131 Naples Italy emilia.pedone@cnr.it., Malgieri G; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies - University of Campania 'Luigi Vanvitelli' Via Vivaldi 43 81100 Caserta Italy gaetano.malgieri@unicampania.it roberto.fattorusso@unicampania.it., Pedone EM; CNR - Institute of Biostructures and Bioimaging Via Pietro Castellino 111 80131 Naples Italy emilia.pedone@cnr.it., Fattorusso R; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies - University of Campania 'Luigi Vanvitelli' Via Vivaldi 43 81100 Caserta Italy gaetano.malgieri@unicampania.it roberto.fattorusso@unicampania.it.

Publikováno v: Chemical science [Chem Sci] 2024 May 01; Vol. 15 (23), pp. 8858-8872. Date of Electronic Publication: 2024 May 01 (Print Publication: 2024).

Biophysical and Structural Characterization of the Interaction between Human Galectin-3 and the Lipopolysaccharide from Pseudomonas aeruginosa .

Autor: Pirone L; Institute of Biostructures and Bioimaging, National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy., Lenza MP; Department of Chemical Sciences, University of Naples Federico II, Via Cinthia 4, 80126 Naples, Italy., Di Gaetano S; Institute of Biostructures and Bioimaging, National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.; Interuniversity Research Centre on Bioactive Peptides (CIRPEB), University of Naples Federico II, 80134 Naples, Italy., Capasso D; Interuniversity Research Centre on Bioactive Peptides (CIRPEB), University of Naples Federico II, 80134 Naples, Italy.; Department of Physics 'Ettore Pancini', University of Naples Federico II, Via Cinthia 4, 80126 Naples, Italy., Filocaso M; Institute of Biostructures and Bioimaging, National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli', 81100 Caserta, Italy.; Institute of Crystallography, National Research Council (CNR), 81100 Caserta, Italy., Russo R; Institute of Biostructures and Bioimaging, National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli', 81100 Caserta, Italy., Di Carluccio C; Department of Chemical Sciences, University of Naples Federico II, Via Cinthia 4, 80126 Naples, Italy., Saviano M; Interuniversity Research Centre on Bioactive Peptides (CIRPEB), University of Naples Federico II, 80134 Naples, Italy.; Institute of Crystallography, National Research Council (CNR), 81100 Caserta, Italy., Silipo A; Department of Chemical Sciences, University of Naples Federico II, Via Cinthia 4, 80126 Naples, Italy., Pedone E; Institute of Biostructures and Bioimaging, National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.; Interuniversity Research Centre on Bioactive Peptides (CIRPEB), University of Naples Federico II, 80134 Naples, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 01; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 01.

ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription.

Autor: Gorodetska I; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Offermann A; Institute of Pathology, University Hospital Schleswig-Holstein, Luebeck, Germany; Pathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany., Püschel J; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Lukiyanchuk V; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Gaete D; Institute of Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, Dresden, Germany., Kurzyukova A; Technische Universität Dresden, CRTD - Center for Regenerative Therapies TU Dresden and Center for Healthy Aging, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Freytag V; Institute of Anatomy and Experimental Morphology, Center for Experimental Medicine, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Germany., Haider MT; Institute of Anatomy and Experimental Morphology, Center for Experimental Medicine, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Germany., Fjeldbo CS; Department of Radiation Biology, Oslo University Hospital, Oslo, Norway., Di Gaetano S; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Schwarz FM; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany.; German Cancer Consortium (DKTK), partner site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany., Patil S; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany.; German Cancer Consortium (DKTK), partner site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany., Borkowetz A; Department of Urology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany., Erb HHH; Department of Urology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany., Baniahmad A; Institute of Human Genetics, Jena University Hospital, Friedrich Schiller University, Jena, Germany., Mircetic J; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; German Cancer Consortium (DKTK), partner site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany., Lyng H; Department of Radiation Biology, Oslo University Hospital, Oslo, Norway.; Department of Physics, University of Oslo, Oslo, Norway., Löck S; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; German Cancer Consortium (DKTK), partner site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site Dresden: German Cancer Research Center (DKFZ), Heidelberg; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Linge A; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; German Cancer Consortium (DKTK), partner site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site Dresden: German Cancer Research Center (DKFZ), Heidelberg; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Lange T; Institute of Anatomy and Experimental Morphology, Center for Experimental Medicine, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Germany.; Institute of Anatomy I, Cancer Center Central Germany, Jena, University Hospital, Jena, Germany., Knopf F; Technische Universität Dresden, CRTD - Center for Regenerative Therapies TU Dresden and Center for Healthy Aging, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Wielockx B; Institute of Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, Dresden, Germany., Krause M; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany.; German Cancer Consortium (DKTK), partner site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site Dresden: German Cancer Research Center (DKFZ), Heidelberg; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Perner S; Institute of Pathology, University Hospital Schleswig-Holstein, Luebeck, Germany; Pathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany., Dubrovska A; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany.; German Cancer Consortium (DKTK), partner site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site Dresden: German Cancer Research Center (DKFZ), Heidelberg; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.

Publikováno v: Theranostics [Theranostics] 2024 Jan 01; Vol. 14 (2), pp. 714-737. Date of Electronic Publication: 2024 Jan 01 (Print Publication: 2024).