Zobrazeno 1 - 10
of 32
pro vyhledávání: '"DHT, dihydrotestosterone"'
Autor:
Deidre M. Mattiske, Andrew J Pask
Publikováno v:
Current Research in Toxicology, Vol 2, Iss, Pp 179-191 (2021)
Current Research in Toxicology
Current Research in Toxicology
Graphical abstract
Highlights • Penis development is regulated by a tight balance of androgens and estrogens. • EDCs that impact androgen/estrogen balance during development cause hypospadias. • Cross-disciplinary collaborations are needed
Highlights • Penis development is regulated by a tight balance of androgens and estrogens. • EDCs that impact androgen/estrogen balance during development cause hypospadias. • Cross-disciplinary collaborations are needed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6a4feece5728c2a57646b8ca982bb7
https://doi.org/10.1016/j.crtox.2021.03.004
https://doi.org/10.1016/j.crtox.2021.03.004
Autor:
Xueying Tian, Bin Zhou
Publikováno v:
The Journal of Biological Chemistry
Site-specific recombinases (SSRs) are invaluable genome engineering tools that have enormously boosted our understanding of gene functions and cell lineage relationships in developmental biology, stem cell biology, regenerative medicine, and multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd835550bfb4c5ce331da13d1125a3f
http://europepmc.org/articles/PMC8050033
http://europepmc.org/articles/PMC8050033
Autor:
Elena Ortona, Valentina Giudice, Andrea Cignarella, Marina Ziche, Amelia Filippelli, Silvia De Francia, Vincenzo Brancaleone, Andrea Spini, Luigia Trabace, Anna Ruggieri, Maria Grazia Morgese
Publikováno v:
Pharmacological Research
Pharmacological Research, 2021, 173, pp.105848. ⟨10.1016/j.phrs.2021.105848⟩
Pharmacological Research, 2021, 173, pp.105848. ⟨10.1016/j.phrs.2021.105848⟩
Making gender bias visible allows to fill the gaps in knowledge and understand health records and risks of women and men. The coronavirus disease 2019 (COVID-19) pandemic has shown a clear gender difference in health outcomes. The more severe symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3220f6ea3907610cc7e81df83b367a62
http://hdl.handle.net/2318/1798821
http://hdl.handle.net/2318/1798821
Autor:
Ken-ichi Shinohara, Jun Luo, Kosuke Higuchi, Tomomi Furihata, Shinichi Sakamoto, Masaki Fukuyo, Naohiko Anzai, Tomohiko Ichikawa, Manato Kanesaka, Akira Komiya, Atsushi Kaneda, Yusuke Imamura, Atsushi Okabe, Bahityar Rahmutulla, Yasunobu Mano, Yoshikatsu Kanai, Hiroaki Sato, Maihulan Maimaiti, Masahiro Sugiura
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100915-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100915-(2021)
Highlights • The entire landscape of AR-V7 target regions/genes in CRPC cells was investigated. • We identified 78 AR-V7 target genes, targeted specifically by AR-V7 e.g. SLC3A2, or commonly by AR and AR-V7 e.g. NUP210. • SLC3A2 and NUP210 were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf8b79e13072e7cfb11dc85bfef3e57
http://europepmc.org/articles/PMC7581977
http://europepmc.org/articles/PMC7581977
Autor:
Lutz, S.Z., Hennenlotter, J., Scharpf, M.O., Sailer, C., Fritsche, L., Schmid, V., Kantartzis, K., Wagner, R., Lehmann, R., Berti, L., Peter, A., Staiger, H., Fritsche, A., Fend, A., Todenhöfer, T., Stenzl, A., Häring, H.-U., Heni, M.
Publikováno v:
Molecular Metabolism, Vol 8, Iss, Pp 158-166 (2018)
Molecular Metabolism
Mol. Metab. 8, 158-166:doi:10.1016/j.molmet.2017.11.013 (2017)
Molecular Metabolism
Mol. Metab. 8, 158-166:doi:10.1016/j.molmet.2017.11.013 (2017)
Objective While prostate cancer does not occur more often in men with diabetes, survival is markedly reduced in this patient group. Androgen signaling is a known and major driver for prostate cancer progression. Therefore, we analyzed major component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dbbf37fcad2fa13131b37a333a6ed1d8
http://www.sciencedirect.com/science/article/pii/S2212877817306841
http://www.sciencedirect.com/science/article/pii/S2212877817306841
Publikováno v:
Cellular Signalling
In some types of human cancer, aldehyde dehydrogenases represent stemness markers and their expression is associated with advanced disease stages and poor prognosis. Although several biological functions are mediated by their product Retinoid acid, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1457905c555ffd74710c72192f7cc6ce
https://doi.org/10.1016/j.cellsig.2021.110120
https://doi.org/10.1016/j.cellsig.2021.110120
Publikováno v:
Neoplasia (New York, N.Y.)
Prostate cancer generally metastasizes to bone, and most patients have tumor cells in their bone marrow already at diagnosis. Tumor cells at the metastatic site may therefore progress in parallel with those in the primary tumor. Androgen deprivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::632ba32479983c929eaca082a84fae7c
http://europepmc.org/articles/PMC4796808
http://europepmc.org/articles/PMC4796808
Publikováno v:
Arab Journal of Urology
Objective To evaluate the incidence of benign prostatic hyperplasia (BPH) and metabolic syndrome in patients with androgenetic alopecia (AGA) in comparison with those with no AGA, as several previous studies have reported inconsistent results of an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadf907b8a86b9c331e6b96cc53cdf83
http://europepmc.org/articles/PMC4963145
http://europepmc.org/articles/PMC4963145
Autor:
I A Hughes, Philippa Prentice, Trevor Bunch, Ngee Lek, Nigel P. Mongan, Jonathan B Whitchurch, Veronika M. Metzler, Karolina Zielińska, Harriet L Miles, David M. Heery, Rieko Tadokoro-Cuccaro, Bismoy Mazumder
Publikováno v:
EBioMedicine
Background: PAIS exhibits a complex spectrum of phenotypes and pubertal outcomes. The paucity of reliable prognostic indicators can confound management decisions including sex-of rearing. We assessed whether external masculinisation score (EMS) at bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eff04599ed1218a15cf9b5a35e4c63d
https://doi.org/10.2139/ssrn.3228238
https://doi.org/10.2139/ssrn.3228238
Autor:
Zaslavsky, Alexander B., Gloeckner-Kalousek, Audrey, Adams, Mackenzie, Putluri, Nagireddy, Venghatakrishnan, Harene, Li, Hangwen, Morgan, Todd M., Feng, Felix Y., Tewari, Muneesh, Sreekumar, Arun, Palapattu, Ganesh S.
Publikováno v:
Neoplasia (New York, N.Y.)
Platelets have been long postulated to play a critical role in the pathogenesis of prostate cancer, although relatively little is known regarding the precise mechanisms involved. Androgen deprivation therapy (ADT) for prostate cancer eventually fails
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f20da8ae614ddce9ffb417b435909c5
http://europepmc.org/articles/PMC4719002
http://europepmc.org/articles/PMC4719002