Author Correction: The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression.

Autor: Nam GH; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea., Jo KJ; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea., Park YS; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea., Kawk HW; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea., Yoo JG; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea., Jang JD; Doori Cosmetics Co.,Ltd., 11F Galaxy Tower, 175, Saimdang-ro, Seocho-gu, Seoul, South Korea., Kang SM; ANPEP INC. 13, Oksansandan 1-ro, Oksan-myeon, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea., Kim SY; Department of Food Science & Bio Technology, Shinansan University, Daehakro Danwon-gu, Ansan-city, Gyenggi-do, South Korea., Kim YM; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea. ym1938@naver.com.

Publikováno v: Scientific reports [Sci Rep] 2020 May 19; Vol. 10 (1), pp. 8571. Date of Electronic Publication: 2020 May 19.

The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

Autor: Jin Dong Jang, Sang-Yong Kim, Hye Won Kawk, Sang Moon Kang, Je-Geun Yoo, Kyung-Jo Jo, Young Min Kim, Gun He Nam, Ye-Seul Park

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

The Trapa japonica fruit is a natural plant growing in ponds with its roots in the mud. It has long been used as a home remedy for many diseases; however, a major problem with this kind of natural extract is the multicomponents-multitargets for disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943c130855dc3932c893094dfcabefc6
http://europepmc.org/articles/PMC6858360

Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone

Autor: Thomas A. Kost, J. Darren Stuart, Deborah Simpson Noel, Laurie K. Overton, Sue H. Kadwell, Timothy K. Tippin, H. Neal Bramson, Kenneth Batchelor, Russell L. Yeager, Christine R. Hoffman, Frank Lee

Publikováno v: Biochemical Pharmacology. 62:933-942

The interaction of baculovirus expressed rat steroid 5alpha-reductase types 1 and 2 (r5AR1 and r5AR2) with 17beta-N-(2,5-bis(trifluoromethyl)phenyl)carbamoyl-4-aza-5alpha-androst-1-en-3-one (GI198745) was investigated at pH 7 and 37 degrees. This 5al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f86e8b2553057aa1154a62c9e57b7bd
https://doi.org/10.1016/s0006-2952(01)00728-6

Endocrine disrupting chemicals in the pathogenesis of hypospadias; developmental and toxicological perspectives

Autor: Deidre M. Mattiske, Andrew J Pask

Publikováno v: Current Research in Toxicology, Vol 2, Iss, Pp 179-191 (2021)
Current Research in Toxicology

Graphical abstract
Highlights • Penis development is regulated by a tight balance of androgens and estrogens. • EDCs that impact androgen/estrogen balance during development cause hypospadias. • Cross-disciplinary collaborations are needed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6a4feece5728c2a57646b8ca982bb7
https://doi.org/10.1016/j.crtox.2021.03.004

Sex-tailored pharmacology and COVID-19: next steps towards appropriateness and health equity

Autor: Elena Ortona, Valentina Giudice, Andrea Cignarella, Marina Ziche, Amelia Filippelli, Silvia De Francia, Vincenzo Brancaleone, Andrea Spini, Luigia Trabace, Anna Ruggieri, Maria Grazia Morgese

Publikováno v: Pharmacological Research
Pharmacological Research, 2021, 173, pp.105848. ⟨10.1016/j.phrs.2021.105848⟩

Making gender bias visible allows to fill the gaps in knowledge and understand health records and risks of women and men. The coronavirus disease 2019 (COVID-19) pandemic has shown a clear gender difference in health outcomes. The more severe symptom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3220f6ea3907610cc7e81df83b367a62
http://hdl.handle.net/2318/1798821