Zobrazeno 1 - 10
of 13
pro vyhledávání: '"DHAP, dihydroxyacetone phosphate"'
Autor:
Margarita Gerou, Benjamin A. Hall, Scott P. Allen, Kathrin Meyer, Pamela J. Shaw, Ryan Woof, Jessica Allsop, Stephen J. Kolb
Publikováno v:
Neurobiology of Aging
Highlights • Aging affects the metabolic profile of fibroblasts derived from ALS cases • Increased NADH metabolism with age is observed in the presence of a specific set of catabolic energy substrates in healthy individuals • Reduced NADH metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa322bad33369b41380c3947538e1343
http://europepmc.org/articles/PMC8346650
http://europepmc.org/articles/PMC8346650
Autor:
Pimchai Chaiyen, Jirawat Tantipisit, Asweena Binlaeh, Litavadee Chuaboon, Juthamas Jaroensuk, Somchart Maenpuen, Penchit Chitnumsub, Ruchanok Tinikul, Aritsara Jaruwat, Jittima Phonbuppha, Pratchaya Watthaisong, Narin Lawan
Publikováno v:
The Journal of Biological Chemistry
Aldolases catalyze the reversible reactions of aldol condensation and cleavage and have strong potential for the synthesis of chiral compounds, widely used in pharmaceuticals. Here, we investigated a new Class II metal aldolase from the p-hydroxyphen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ec40387511a3835e3f518a5fda0050
http://europepmc.org/articles/PMC8560999
http://europepmc.org/articles/PMC8560999
Publikováno v:
Metabolism Open, Vol 9, Iss, Pp 100086-(2021)
Metabolism Open
Metabolism Open
Background In our recent study using [U–13C3]glycerol, a small subset of hamsters showed an unusual profile of glycerol metabolism: negligible gluconeogenesis from glycerol plus conversion of glycerol to 1,3-propanediol (1,3PDO) and 3-hydroxypropio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675290128f116ea040e00c4c3e286fbe
http://www.sciencedirect.com/science/article/pii/S2589936821000104
http://www.sciencedirect.com/science/article/pii/S2589936821000104
Publikováno v:
The Journal of Biological Chemistry
Previous studies have identified GAPDH as a promising target for treating cancer and modulating immunity because its inhibition reduces glycolysis in cells (cancer cells and immune cells) with the Warburg effect, a modified form of cellular metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d332adf7ec310c14c988541e3e3aa008
https://pubmed.ncbi.nlm.nih.gov/33545174
https://pubmed.ncbi.nlm.nih.gov/33545174
Publikováno v:
Redox Biology
Redox Biology, Vol 20, Iss, Pp 130-145 (2019)
Redox Biology, Vol 20, Iss, Pp 130-145 (2019)
Low molecular weight (LMW) thiols play an important role as thiol-cofactors for many enzymes and are crucial to maintain the reduced state of the cytoplasm. Most Gram-negative bacteria utilize glutathione (GSH) as major LMW thiol. However, in Gram-po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f489c6dc700b786fd74ac141fe7a87
http://europepmc.org/articles/PMC6178380
http://europepmc.org/articles/PMC6178380
Autor:
Héctor, Acosta, Richard, Burchmore, Christina, Naula, Melisa, Gualdrón-López, Ender, Quintero-Troconis, Ana J, Cáceres, Paul A M, Michels, Juan Luis, Concepción, Wilfredo, Quiñones
Publikováno v:
Molecular and Biochemical Parasitology
Graphical abstract
Highlights • New metabolic routes and membrane proteins were identified in the organelles. • Exponential and stationary growth-phase cells vary little in glycosomal proteins. • A variety of proteins bearing a typical PTS
Highlights • New metabolic routes and membrane proteins were identified in the organelles. • Exponential and stationary growth-phase cells vary little in glycosomal proteins. • A variety of proteins bearing a typical PTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f4916d5902a8e2f6bc792a94e5964a9
https://pubmed.ncbi.nlm.nih.gov/30831156
https://pubmed.ncbi.nlm.nih.gov/30831156
Autor:
Thorsten Forster, Manu Verma, Tak Yung Man, Megan C. Holmes, Zhenguang Zhang, Natalie Z.M. Homer, Tiina Kipari, Karen E. Chapman, Jonathan R. Seckl
Publikováno v:
Verma, M, Kipari, T, Zhang, Z, Man, T Y, Forster, T, Homer, N Z M, Seckl, J R, Holmes, M C & Chapman, K E 2017, ' 11β-hydroxysteroid dehydrogenase-1 deficiency alters brain energy metabolism in acute systemic inflammation ', Brain, Behavior, and Immunity . https://doi.org/10.1016/j.bbi.2017.11.015
Brain, Behavior, and Immunity
Brain, Behavior, and Immunity
Highlights • 11β-HSD1-deficiency reduces the hippocampal inflammatory response to LPS. • This happens despite similar peripheral inflammation. • 11β-HSD1-deficiency favours a “Warburg” like response to LPS in the hippocampus. • LPS incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebcbfbdd2ee3a67bd429f3d5fdeb6e02
https://hdl.handle.net/20.500.11820/87e3bca5-01b4-4b24-9959-af9148236678
https://hdl.handle.net/20.500.11820/87e3bca5-01b4-4b24-9959-af9148236678
Akademický článek
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Akademický článek
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Autor:
Myers TD; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, USA., Ferguson C; Department of Anesthesiology and Preoperative Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Gliniak E; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, USA., Homanics GE; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Anesthesiology and Preoperative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA., Palladino MJ; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, USA.
Publikováno v:
Current research in neurobiology [Curr Res Neurobiol] 2022 Nov 09; Vol. 3, pp. 100062. Date of Electronic Publication: 2022 Nov 09 (Print Publication: 2022).