Zobrazeno 1 - 10
of 38
pro vyhledávání: '"DHANYA MADHU"'
Autor:
Mohamed Abu-Farha, Dhanya Madhu, Prashantha Hebbar, Anwar Mohammad, Arshad Channanath, Sina Kavalakatt, Nada Alam-Eldin, Fatima Alterki, Ibrahim Taher, Osama Alsmadi, Mohammad Shehab, Hossein Arefanian, Rasheed Ahmad, Thangavel Alphonse Thanaraj, Fahd Al-Mulla, Jehad Abubaker
Publikováno v:
Cells, Vol 12, Iss 21, p 2563 (2023)
Background: Angiopoietin-like protein 8 (ANGPTL8) is known to regulate lipid metabolism and inflammation. It interacts with ANGPTL3 and ANGPTL4 to regulate lipoprotein lipase (LPL) activity and with IKK to modulate NF-κB activity. Further, a single
Externí odkaz:
https://doaj.org/article/58af7644c19a46d09ac517ee0f9f76a1
Increased expression level of ANGPTL8 in white adipose tissue under acute and chronic cold treatment
Autor:
Hossein Arefanian, Irina Al-Khairi, Nermeen Abu Khalaf, Preethi Cherian, Sina Kavalakatt, Dhanya Madhu, Aditi Mathur, Mohamed G. Qaddoumi, Fahd Al-Mulla, Jehad Abubaker, Mohamed Abu-Farha
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-11 (2021)
Abstract Background Angiopoietin-like proteins (ANGPTL), primarily 3, 4, and 8, play a major role in maintaining energy homeostasis by regulating triglyceride metabolism. This study evaluated the level of ANGPTL3, 4, and 8 in the liver, brown adipose
Externí odkaz:
https://doaj.org/article/24d822369137408885ffe9dcfdf6d791
Autor:
Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Heikki A. Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Jehad Abubaker, Ali Tiss
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The neuropeptide urocortin 3 (UCN3) has a beneficial effect on metabolic disorders, such as obesity, diabetes, and cardiovascular disease. It has been reported that UCN3 regulates insulin secretion and is dysregulated with increasing severit
Externí odkaz:
https://doaj.org/article/f231d71be668489eae2c831192bc9068
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-3 (2020)
Abstract Fetuin-A (Fet-A) was one of the first hepatokines to be reportedly linked to metabolic diseases. Fet-A was also suggested to be an adipokine, but its expression in the adipose tissue remains debatable. Here we compared the expression of Fet-
Externí odkaz:
https://doaj.org/article/d62c3641bb5f4c0fb39035188ae88fc9
Autor:
Abdelkrim Khadir, Sina Kavalakatt, Dhanya Madhu, Maha Hammad, Sriraman Devarajan, Jaakko Tuomilehto, Ali Tiss
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-13 (2018)
Abstract Background The hepatokine fetuin-A is linked to obesity and type 2 diabetes, but its presence and expression in adipose tissue remain unclear. In this study, we aimed to assess the circulating levels of fetuin-A and its expression in subcuta
Externí odkaz:
https://doaj.org/article/84df3159e6484bcdb0752963328d4310
Autor:
Abdelkrim Khadir, Dhanya Madhu, Sina Kavalakatt, Preethi Cherian, Monira Alarouj, Abdullah Bennakhi, Jehad Abubaker, Ali Tiss, Naser Elkum
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227606 (2020)
Cardiovascular disease (CVD) risks persist in patients despite treatment. CVD susceptibility also varies with sex and ethnicity and is not entirely explained by conventional CVD risk factors. The aim of the present study was to identify novel CVD can
Externí odkaz:
https://doaj.org/article/4b921d6db4cd4ef59587c46e797b530f
Autor:
Sina Kavalakatt, Abdelkrim Khadir, Shihab Kochumon, Dhanya Madhu, Sriraman Devarajan, Maha Hammad, Nada Alam-Eldin, Samia Warsame, Hessa Al-Kandari, Maria AlMahdi, Rasheed Ahmad, Heikki A. Koistinen, Jaakko Tuomilehto, Fahd Al-Mulla, Jehad Abubaker, Ali Tiss
Publikováno v:
Nutrients, Vol 14, Iss 3, p 429 (2022)
The corticotropin-releasing hormone (CRH) and urocortins (UCNs) have been implicated in energy homeostasis and the cellular stress response. However, the expression of these neuropeptides in children remains unclear. Therefore, we determined the impa
Externí odkaz:
https://doaj.org/article/524730b1545144f0b430a62566c5f9a0
Autor:
Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Maha Hammad, Sriraman Devarajan, Jehad Abubaker, Fahd Al-Mulla, Jaakko Tuomilehto, Ali Tiss
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Urocortin3 (UCN3) regulates metabolic functions and is involved in cellular stress response. Although UCN3 is expressed in human adipose tissue, the association of UCN3 with obesity and diabetes remains unclear. This study investigated the effects of
Externí odkaz:
https://doaj.org/article/49a23bbb2cff475fb4cf043c8a079e6c
Autor:
Abdelkrim Khadir, Sina Kavalakatt, Dhanya Madhu, Preethi Cherian, Fahd Al-Mulla, Jehad Abubaker, Ali Tiss
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2056 (2020)
Epoxide hydrolase 2 (EPHX2) is an emerging therapeutic target in several immunometabolic disorders. EPHX2 metabolizes anti-inflammatory epoxyeicosatrienoic acids into pro-inflammatory diols. The contribution of EPHX2 activity to human obesity remains
Externí odkaz:
https://doaj.org/article/51a4c448fd12469684196f85500ecdcb
Autor:
Mohamed Abu-Farha, Preethi Cherian, Irina Al-Khairi, Dhanya Madhu, Ali Tiss, Samia Warsam, Asma Alhubail, Devarajan Sriraman, Faisal Al-Refaei, Jehad Abubaker
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173024 (2017)
ANGPTL7 is a member of the Angiopoietin-like (ANGPTL) protein family that is composed of eight proteins (1-8). Increasing evidence is associating ANGPTL proteins to obesity and insulin resistance. The biological role of ANGPTL7 is yet to be understoo
Externí odkaz:
https://doaj.org/article/437ae70b70e24e72b3460c5c644c6314