Zobrazeno 1 - 10
of 54
pro vyhledávání: '"DH Boschelli"'
Autor:
William A. Denny, Jeffrey Bruce Smaill, AM Doherty, James M. Hamby, Alan J. Kraker, Brian D. Palmer, TK Dahring, JB Kramer, DH Boschelli, Khatana Ss, Maruta Boyd, Robert L. Panek, R. T. Winters, Gina H. Lu, H. D. H. Showalter
Publikováno v:
Journal of medicinal chemistry. 41(27)
1-Phenylbenzimidazoles are shown to be a new class of ATP-site inhibitors of the platelet-derived growth factor receptor (PDGFR). Structure-activity relationships (SARs) are narrow, with closely related heterocycles being inactive. A systematic study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b1b5f2bcf503f1d520e1f7178e91ca
https://pubmed.ncbi.nlm.nih.gov/9876115
https://pubmed.ncbi.nlm.nih.gov/9876115
Autor:
Tumey LN; Pfizer Global R&D, 445 Eastern Point Rd., Groton, CT 06340, USA. Electronic address: Nathan.tumey@pfizer.com., Boschelli DH; Pfizer Global R&D, 445 Eastern Point Rd., Groton, CT 06340, USA., Bhagirath N; Pfizer Global R&D, 445 Eastern Point Rd., Groton, CT 06340, USA., Shim J; Pfizer Global R&D, 445 Eastern Point Rd., Groton, CT 06340, USA., Murphy EA; Pfizer Global R&D, 200 Cambridge Park Dr., Cambridge, MA 02140, USA., Goodwin D; Pfizer Global R&D, 200 Cambridge Park Dr., Cambridge, MA 02140, USA., Bennett EM; Pfizer Global R&D, 87 Cambridgepark Dr., Cambridge, MA 02140, USA., Wang M; Pfizer Global R&D, 1 Burtt Rd., Andover, MA 01810, USA., Lin LL; Pfizer Global R&D, 200 Cambridge Park Dr., Cambridge, MA 02140, USA., Press B; Pfizer Global R&D, 445 Eastern Point Rd., Groton, CT 06340, USA., Shen M; Pfizer Global R&D, 200 Cambridge Park Dr., Cambridge, MA 02140, USA., Frisbie RK; Pfizer Global R&D, 445 Eastern Point Rd., Groton, CT 06340, USA., Morgan P; Pfizer Global R&D, 200 Cambridge Park Dr., Cambridge, MA 02140, USA., Mohan S; Pfizer Global R&D, 200 Cambridge Park Dr., Cambridge, MA 02140, USA., Shin J; Pfizer Global R&D, 200 Cambridge Park Dr., Cambridge, MA 02140, USA., Rao VR; Pfizer Global R&D, 200 Cambridge Park Dr., Cambridge, MA 02140, USA.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2014 May 01; Vol. 24 (9), pp. 2066-72. Date of Electronic Publication: 2014 Mar 29.
Autor:
Murrills RJ; Department of Osteoporosis and Frailty, Women's Health and Musculoskeletal Biology, Wyeth Research, Collegeville, Pennsylvania, USA. murrills@aol.com, Fukayama S, Boschelli F, Matteo JJ, Owens J, Golas JM, Patel D, Lane G, Liu YB, Carter L, Jussif J, Spaulding V, Wang YD, Boschelli DH, McKew JC, Li XJ, Lockhead S, Milligan C, Kharode YP, Diesl V, Bai Y, Follettie M, Bex FJ, Komm B, Bodine PV
Publikováno v:
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2012 Mar; Vol. 340 (3), pp. 676-87. Date of Electronic Publication: 2011 Dec 09.
Autor:
Boschelli DH; Wyeth Research, Chemical Sciences 401 N. Middletown Road, Pearl River, NY 10965, United States. bosched@wyeth.com, Wang D, Wang Y, Wu B, Honores EE, Barrios Sosa AC, Chaudhary I, Golas J, Lucas J, Boschelli F
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2010 May 01; Vol. 20 (9), pp. 2924-7. Date of Electronic Publication: 2010 Mar 07.
Autor:
Boschelli DH; Wyeth Research, Pearl River, NY 10965, USA. bosched@wyeth.com, Subrath J, Niu C, Wu B, Wang Y, Lee J, Brennan A, Ho M, Deng B, Yang X, Xu X, Leung L, Wang J, Atherton J, Chaudhary D
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2010 Mar 15; Vol. 20 (6), pp. 1965-8. Date of Electronic Publication: 2010 Jan 28.
Autor:
Tumey LN; Wyeth Research, Medicinal Chemistry, 401 N. Middletown Rd., Pearl River, NY 10965, United States. tumeyn@wyeth.com, Bhagirath N, Brennan A, Brooijmans N, Lee J, Yang X, Boschelli DH
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2009 Dec 01; Vol. 17 (23), pp. 7933-48. Date of Electronic Publication: 2009 Oct 31.
Autor:
Shim J; Chemical Sciences, Wyeth Research, Pearl River, NY 10965, USA. shimj@wyeth.com, Eid C, Lee J, Liu E, Chaudhary D, Boschelli DH
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Dec 01; Vol. 19 (23), pp. 6575-7. Date of Electronic Publication: 2009 Oct 13.
Autor:
Liang S; Discovery Neuroscience, Wyeth Research, CN-8000, Princeton, NJ 08543, USA., Pong K, Gonzales C, Chen Y, Ling HP, Mark RJ, Boschelli F, Boschelli DH, Ye F, Barrios Sosa AC, Mansour TS, Frost P, Wood A, Pangalos MN, Zaleska MM
Publikováno v:
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2009 Dec; Vol. 331 (3), pp. 827-35. Date of Electronic Publication: 2009 Sep 09.
Autor:
Niu C; Wyeth Research, Chemical Sciences, 401 N. Middletown Road, Pearl River, NY 10965, USA. niuc@wyeth.com, Boschelli DH, Tumey LN, Bhagirath N, Subrath J, Shim J, Wang Y, Wu B, Eid C, Lee J, Yang X, Brennan A, Chaudhary D
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Oct 15; Vol. 19 (20), pp. 5829-32. Date of Electronic Publication: 2009 Aug 29.
Autor:
Prashad AS; Wyeth Research, Chemical Sciences, 401 N. Middletown Road, Pearl River, NY 10965, United States. prashaa@wyeth.com, Wang D, Subrath J, Wu B, Lin M, Zhang MY, Kagan N, Lee J, Yang X, Brennan A, Chaudhary D, Xu X, Leung L, Wang J, Boschelli DH
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Oct 01; Vol. 19 (19), pp. 5799-802. Date of Electronic Publication: 2009 Jul 28.