Zobrazeno 1 - 10
of 1 131
pro vyhledávání: '"DFO"'
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-21 (2024)
Abstract Background During the previous two decades, PET imaging of biopharmaceuticals radiolabeled with zirconium-89 has become a consistent tool in preclinical and clinical drug development and patient selection, primarily due to its advantageous p
Externí odkaz:
https://doaj.org/article/bc06d18625874015acb5db58734cf373
Autor:
Falguni Basuli, Olga Vasalatiy, Jianfeng Shi, Kelly C. Lane, Freddy E. Escorcia, Rolf E. Swenson
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 480 (2024)
Desferrioxamine B (DFO) is the clinical standard chelator for preparing zirconium-89 labeled antibodies. In the current study, the stabilities of a zirconium-89 labeled panitumumab (PAN; Vectibix®) with three different chelators (DFO, DFO*, and DOTA
Externí odkaz:
https://doaj.org/article/1aa628e7299d4879ab489d3b3fd35fe8
Autor:
Sathesh Abraham Leo E, Nattar Kannan K
Publikováno v:
Iraqi Journal for Computer Science and Mathematics, Vol 5, Iss 1 (2024)
The prostate cancer is a deadly form of cancer that assassinates a significant number of men due of its mediocre identification process. Images from people with cancer include important and intricate details that are difficult for conventional diagno
Externí odkaz:
https://doaj.org/article/cb7d65fe2ab7490ba213a77f1ec74dcf
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24656- (2024)
Diabetic foot ulcer (DFU) is a chronic complication of diabetes. Wound healing in patients with DFU is generally very slow, with a high recurrence rate even after the ulcer healed. The DFU remains a major clinical challenge due to a lack of understan
Externí odkaz:
https://doaj.org/article/a5288915625a4c6087ce5e5b9314d3fc
Autor:
Nicole Tomasic
Publikováno v:
FACETS, Vol 8, Iss , Pp 1-11 (2023)
Although Canada’s oceans are a public resource, commercial fisheries data are routinely withheld from researchers and the general public by Fisheries and Oceans Canada (DFO) due to privacy obligations. However, data can be released if considered su
Externí odkaz:
https://doaj.org/article/86db51cf2b2044ecae08d116702dd4fd
Autor:
Eleonora Ficiarà, Chiara Molinar, Silvia Gazzin, Sri Jayanti, Monica Argenziano, Lucia Nasi, Francesca Casoli, Franca Albertini, Shoeb Anwar Ansari, Andrea Marcantoni, Giulia Tomagra, Valentina Carabelli, Caterina Guiot, Federico D’Agata, Roberta Cavalli
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 729 (2024)
Excessive iron levels are believed to contribute to the development of neurodegenerative disorders by promoting oxidative stress and harmful protein clustering. Novel chelation treatments that can effectively remove excess iron while minimizing negat
Externí odkaz:
https://doaj.org/article/d9b6674837844e97b31b83aae99c902e
Autor:
Shih-Chuan Tsai, Shiou-Shiow Farn, Wei-Lin Lo, Fang-Yu Ou Yang, Yong-Ching Kang, Liang-Cheng Chen, Kuo-Ting Chen, Jiunn-Wang Liao, Jui-Yin Kung, Jenn-Tzong Chen, Feng-Yun J. Huang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17132 (2023)
89Zr-iPET has been widely used for preclinical and clinical immunotherapy studies to predict patient stratification or evaluate therapeutic efficacy. In this study, we prepared and evaluated 89Zr-DFO-anti-PD-L1-mAb tracers with varying chelator-to-an
Externí odkaz:
https://doaj.org/article/2a67fd7a356e4aa2adf3cadbdf2d808b
Autor:
Yuehang Zhang, Lei Yu, Renjie Qiu, Lisha Cao, Genlan Ye, Rurong Lin, Yongqin Wang, Guobao Wang, Bianxiang Hu, Honghao Hou
Publikováno v:
Materials Today Bio, Vol 21, Iss , Pp 100694- (2023)
In-situ renal tissue engineering is promising yet challenging for renal injury repair and regeneration due to the highly vascularized structure of renal tissue and complex high-oxidative stress and ischemic microenvironment. Herein, a novel biocompat
Externí odkaz:
https://doaj.org/article/f705b590c25b48ecb74eb41429b19f73
Akademický článek
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Autor:
Lenan Xu, Meiling Zhang, Junzhi Pan, Xiangwei Xu, Yawen Zhang, Xue Han, Lina Yin, Lingfeng Chen, Juan Ren, Jie Yu, Yanmei Zhang, Guang Liang, Yi Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Liver fibrosis, a compensatory repair response to chronic liver injury, is caused by various pathogenic factors, and hepatic stellate cell (HSC) activation and phenotypic transformation are regarded as key events in its progression. Ferroptosis, a no
Externí odkaz:
https://doaj.org/article/ac598d55245548938485c11b0199b3e9