Zobrazeno 1 - 10
of 25
pro vyhledávání: '"DF Makower"'
Autor:
Jeffrey S. Abrams, GW Sledge, CE Geyer, T. Lively, VG Kaklamani, JL Berenberg, MP Goetz, JA Olson, Joseph A. Sparano, DL Toppmeyer, M. Keane, Timothy F. Goggins, Kathy S. Albain, S Paik, DF Hayes, Robert Gray, KI Pritchard, T.J. Saphner, Timothy J. Whelan, LI Wagner, Pavan S. Reddy, Peter M. Ravdin, MJ Ellis, Sunil Badve, AM Brufsky, Henry L. Gomez, William C. Wood, IA Mayer, DF Makower, EC Dees
Publikováno v:
Cancer Research. 79:GS4-07
Background: Black race is associated with worse outcomes in localized hormone receptor (HR)-positive breast cancer in population-based and in clinical trial cohorts, whether using self-identified race (Albain et al. JNCI 2009 [PMID: 19584328; Sparano
Autor:
Christine M. Pellegrino, Eleni Andreopoulou, Joseph A. Sparano, M Patel, Jesus Anampa, K Noah, K Fehn, Alice P. Chen, S-y Oh, DF Makower
Publikováno v:
Cancer Research. 77:P6-12
BACKGROUND: PARP, an essential nuclear enzyme, is involved in the recognition of DNA damage and facilitation of DNA base-excision repair (BER). PARP inhibition sensitizes tumor cells to cytotoxic agents which induce DNA damage, including C. Metronomi
Autor:
Robert Gray, Christine Desbiens, Pavan S. Reddy, Elizabeth Claire Dees, Henry L. Gomez, George W. Sledge, Catalin Mahalcioiu, Daniel F. Hayes, Kathy S. Albain, John A. Olson, Charles E. Geyer, Sunil Badve, Deborah Toppmeyer, Joseph A. Sparano, William C. Wood, Matthew P. Goetz, Thomas James Saphner, Tracy Lively, Jeffrey S. Abrams, Ingrid A. Mayer, Jeffrey L. Berenberg, DF Makower, Maccon M. Keane, Virginia G. Kaklamani, Lynne I. Wagner, Timothy F. Goggins, Adam Brufsky, Matthew J. Ellis, Soonmyung Paik
Publikováno v:
JAMA Oncol
Importance A high 21-gene recurrence score (RS) by breast cancer assay is prognostic for distant recurrence of early breast cancer after local therapy and endocrine therapy alone, and for chemotherapy benefit. Objective To describe clinical outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fe41cb58839ae8d294297f0a69ae6a
https://europepmc.org/articles/PMC6777230/
https://europepmc.org/articles/PMC6777230/
Autor:
Charles E. Geyer, J Zujweski, Timothy F. Goggins, Jeffrey L. Berenberg, Daniel F. Hayes, M. Keane, Kathleen I. Pritchard, Adam Brufsky, JN Atkins, IA Mayer, Deborah Toppmeyer, KS Albain, GW Sledge, Virginia G. Kaklamani, E. A. Perez, Elizabeth Claire Dees, H. L. Gomez Moreno, John A. Olson, Joseph A. Sparano, DF Makower, Richard Gray, RP Reddi
Publikováno v:
Cancer Research. 76:P2-08
Background: The Trial Assigning Individualized Options for Treatment (TAILORx) is a prospective trial evaluating the role of endocrine therapy or chemoendocrine therapy in patients 18-75 years of age with estrogen receptor (ER)-positive, HER2-negativ
Autor:
Lisa Wiechmann, Min Huang, Kevin Kalinsky, Kapil N. Bhalla, Warren Fiskus, Abdissa Negassa, DF Makower, Susan Fineberg, Karen Fehn, Christine M. Pellegrino, Yifan Tu, Joseph A. Sparano, R. Katherine Alpaugh, Leslie Montgomery, Dawn L. Hershman, Eleni Andreopoulou
Publikováno v:
Breast Cancer Research and Treatment. 146:145-152
Histone deacetylases (HDACs) are a family of enzymes that regulate chromatin remodeling and gene transcription. Vorinostat is a panHDAC inhibitor that sensitizes breast cancer cells to taxanes and trastuzumab by suppressing HDAC6 and Hsp90 client pro
Autor:
JA Sparano, Philip J. Stella, B Ramaswamy, J Manola, J Leach, Cristina I. Truica, Paula Klein, DF Makower, Gamini S. Soori, Melinda L. Telli, Lori J. Goldstein, Antonio C. Wolff, TR Wassenaar, Adam Brufsky, B Burnette, Kathy D. Miller, Barbara Haley, A Nagarajan, Noah Kornblum
Publikováno v:
Cancer Research. 77:S1-02
Background: Although AIs are an effective treatment for HR-positive MBC, whether used alone or in combination with CDK4/6 inhibitors, resistance to therapy and disease progression invariably develops. Therapeutic options for AI-resistant disease incl
Autor:
Kathleen I. Pritchard, KS Albain, Virginia G. Kaklamani, E. A. Perez, Daniel F. Hayes, C. Dees, Timothy F. Goggins, Deborah Toppmeyer, Adam Brufsky, Charles E. Geyer, JoAnne Zujewski, C. Vallejos, GW Sledge, M. Keane, DF Makower, JN Atkins, Joseph A. Sparano, Richard Gray, IA Mayer, John A. Olson
Publikováno v:
European Journal of Cancer. 51:S714
Autor:
Schneider BP; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN., Zhao F; Dana Farber Cancer Institute-ECOG-ACRIN Biostatistics Center, Boston, MA., Ballinger TJ; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN., Garcia SF; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL., Shen F; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN., Virani S; Aurora Cancer Care-Southern Lakes VLCC, Burlington, WI., Cella D; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL., Bales C; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN., Jiang G; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN., Hayes L; Pink-4-Ever Ending Disparities, Indianapolis, IN., Miller N; Pink-4-Ever Ending Disparities, Indianapolis, IN., Srinivasiah J; Georgia NCORP, Decatur, GA., Stringer-Reasor EM; University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, AL., Chitalia A; MedStar Washington Hospital Center, Washington, DC., Davis AA; Washington University School of Medicine, St Louis, MO., Makower DF; Montefiore Medical Center-Weiler Hospital, New York, NY., Incorvati J; Fox Chase Comprehensive Cancer Center, Philadelphia, PA., Simon MA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL., Mitchell EP; Thomas Jefferson University Hospital, Philadelphia, PA.; Deceased, Baltimore, MD., DeMichele A; University of Pennsylvania, Philadelphia, PA., Miller KD; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN., Sparano JA; Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY., Wagner LI; University of North Carolina, Chapel Hill, NC., Wolff AC; Johns Hopkins University/Sidney Kimmel Comprehensive Cancer Center.
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Aug 20; Vol. 42 (24), pp. 2899-2907. Date of Electronic Publication: 2024 Jun 03.
Autor:
Sparano JA; Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York., Crager M; Exact Sciences Corporation, Redwood City, CA., Gray RJ; Dana-Farber Cancer Institute, Boston., Tang G; University of Pittsburgh, Pittsburgh., Hoag J; Exact Sciences Corporation, Redwood City, CA., Baehner FL; Exact Sciences Corporation, Redwood City, CA., Shak S; Exact Sciences Corporation, Redwood City, CA., Makower DF; Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Albain KS; Loyola University Medical Center, Maywood, IL., Hayes DF; University of Michigan, Ann Arbor, MI., Geyer CE; University of Pittsburgh, Pittsburgh., Dees EC; University of North Carolina, Chapel Hill, NC., Goetz MP; Mayo Clinic, Jacksonville, FL., Olson JA; Washington University School of Medicine, St. Louis, MO., Lively T; National Cancer Institute, National Institutes of Health, Bethesda, MD., Badve SS; Winship Cancer Institute, Emory University, Atlanta., Saphner TJ; Aurora Medical Center, Two Rivers, WI., Whelan TJ; McMaster University, Hamilton, ON, Canada., Kaklamani VG; University of Texas Health, San Antonio, TX., Wolmark N; University of Pittsburgh, Pittsburgh., Sledge GW; Stanford University, Stanford, CA.; Caris Life Sciences, Irving, TX., Stemmer SM; Davidoff Center, Rabin Medical Center, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Publikováno v:
NEJM evidence [NEJM Evid] 2024 Aug; Vol. 3 (8), pp. EVIDoa2300267. Date of Electronic Publication: 2024 Jul 23.
Autor:
Smith KL; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.; Sibley Memorial Hospital, Washington, District of Columbia, USA., Zhao F; Dana Farber Cancer Institute, Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Biostatistics Center, Boston, Massachusetts, USA., Mayer IA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Tevaarwerk AJ; Mayo Clinic Comprehensive Cancer Center, Rochester, Minnesota, USA., Garcia SF; Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Arteaga CL; University of Texas Southwestern Simmons Cancer Center, Dallas, Texas, USA., Symmans WF; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Park BH; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Burnette BL; Cancer Research of Wisconsin and Northern Michigan (CROWN) NCORP, Green Bay, Wisconsin, USA., Makower DF; Montefiore Medical Center, Bronx, New York, USA., Block M; Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, USA., Morley KA; St Joseph Mercy Hospital, Ann Arbor, Michigan, USA., Jani CR; Phoebe Putney Memorial Hospital, Albany, Georgia, USA., Mescher C; Metro-Minnesota Community Oncology Research Consortium, St Louis Park, Minnesota, USA., Dewani SJ; Columbus Oncology and Hematology Associates Inc., Columbus, Ohio, USA., Brown-Glaberman U; University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico, USA., Flaum LE; Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Mayer EL; Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Sikov WM; Women and Infants Hospital of Rhode Island, Providence, Rhode Island, USA., Rodler ET; University of California, Davis, Davis, California, USA., DeMichele AM; University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania, USA., Sparano JA; Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, New York, USA., Wolff AC; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA., Miller KD; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA., Wagner LI; Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA.
Publikováno v:
Cancer [Cancer] 2024 May 15; Vol. 130 (10), pp. 1747-1757. Date of Electronic Publication: 2024 Jan 18.