Zobrazeno 1 - 10
of 148
pro vyhledávání: '"DESMIN-RELATED CARDIOMYOPATHY"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 4 (2019)
See Article by Ma et al
Externí odkaz:
https://doaj.org/article/fa2a2af9e74a4b5687512492466afd74
Autor:
Shuji Ueda, Moeka Nishihara, Yuuki Hioka, Ken-ichi Yoshino, Soichiro Yamada, Minoru Yamanoue, Yasuhito Shirai
Publikováno v:
International journal of molecular sciences, vol 23, iss 19
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11257
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11257
Protein homeostasis, including protein folding, refolding, and degradation, is thought to decline with aging. HSPB5 (also known as αB-crystallin) prevents target protein aggregation as a molecular chaperone and exhibits a cytoprotective function aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6d8c0fb463e6c735684c97bb3b3c02
https://escholarship.org/uc/item/6jf0w46k
https://escholarship.org/uc/item/6jf0w46k
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Nature reviews cardiology. 14(11):637-653
The incidence and prevalence of cardiac diseases, which are the main cause of death worldwide, are likely to increase because of population ageing. Prevailing theories about the mechanisms of ageing feature the gradual derailment of cellular protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::45b9326c7130b3ab2e10f2be0792d6ed
https://research.rug.nl/en/publications/818116ba-5e3b-4ea8-be60-dacd0b07fb37
https://research.rug.nl/en/publications/818116ba-5e3b-4ea8-be60-dacd0b07fb37
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Mutations in αB-crystallin result in proteotoxic cardiomyopathy with desmin mislocalization to protein aggregates. Intermittent fasting ( IF ) is a novel approach to activate transcription factor EB (TFEB), a master regulator of the autop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c022f75f6834518763691b62bcc38152
https://doi.org/10.1161/jaha.118.011863
https://doi.org/10.1161/jaha.118.011863
Publikováno v:
Canadian Journal of Cardiology. 32(9):11-20
Age comprises the single most important risk factor for cardiac disease development. The incidence and prevalence of cardiac diseases, which represents the main cause of death worldwide, will increase even more because of the aging population. A hall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::6b809def49775cc71728dff40a818b01
https://doi.org/10.1016/j.cjca.2016.03.005
https://doi.org/10.1016/j.cjca.2016.03.005
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Trends in cardiovascular medicine, 25(3), 243-247. Elsevier Inc.
TRENDS IN CARDIOVASCULAR MEDICINE, 25(3), 243-247. ELSEVIER SCIENCE LONDON
Meijering, R A M, Henning, R H & Brundel, B J J M 2015, ' Reviving the protein quality control system: Therapeutic target for cardiac disease in the elderly ', Trends in cardiovascular medicine, vol. 25, no. 3, pp. 243-247 . https://doi.org/10.1016/j.tcm.2014.10.013
TRENDS IN CARDIOVASCULAR MEDICINE, 25(3), 243-247. ELSEVIER SCIENCE LONDON
Meijering, R A M, Henning, R H & Brundel, B J J M 2015, ' Reviving the protein quality control system: Therapeutic target for cardiac disease in the elderly ', Trends in cardiovascular medicine, vol. 25, no. 3, pp. 243-247 . https://doi.org/10.1016/j.tcm.2014.10.013
It has been firmly established that ageing constitutes a principal risk factor for cardiac disease. Currently, the underlying mechanisms of ageing that contribute to the initiation or acceleration of cardiac disease are essentially unresolved. Prevai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e17bba43c703f0e26196ae9eced819
https://hdl.handle.net/11370/0078837c-d25b-49ac-a148-e2a548be9e97
https://hdl.handle.net/11370/0078837c-d25b-49ac-a148-e2a548be9e97
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology, Vol 9 (2018)
Although Huntington’s disease is generally considered to be a neurological disorder, there is mounting evidence that heart malfunction plays an important role in disease progression. This is perhaps not unexpected since both cardiovascular and nerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c90718a3cafb4065acbd68d142a39c
https://pubmed.ncbi.nlm.nih.gov/29875678
https://pubmed.ncbi.nlm.nih.gov/29875678