Zobrazeno 1 - 10
of 29 760
pro vyhledávání: '"DESCRIPTORS"'
Autor:
Folorunsho Bright Omage, José Augusto Salim, Ivan Mazoni, Inácio Henrique Yano, Luiz Borro, Jorge Enrique Hernández Gonzalez, Fabio Rogerio de Moraes, Poliana Fernanda Giachetto, Ljubica Tasic, Raghuvir Krishnaswamy Arni, Goran Neshich
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3907-3919 (2024)
Allosteric regulation plays a crucial role in modulating protein functions and represents a promising strategy in drug development, offering enhanced specificity and reduced toxicity compared to traditional active site inhibition. Existing computatio
Externí odkaz:
https://doaj.org/article/9bff8d03e0ca4d84b751b1eae9667495
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2964-2977 (2024)
Artificial Intelligence is transforming drug discovery, particularly in the hit identification phase of therapeutic compounds. One tool that has been instrumental in this transformation is Quantitative Structure-Activity Relationship (QSAR) analysis.
Externí odkaz:
https://doaj.org/article/13bc196e36e14e1a8560a9f8872d564e
Autor:
Georgina B. Armstrong, Vidhi Shah, Paula Sanches, Mitul Patel, Ricky Casey, Craig Jamieson, Glenn A. Burley, William Lewis, Zahra Rattray
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2345-2357 (2024)
The formulation of high-concentration monoclonal antibody (mAb) solutions in low dose volumes for autoinjector devices poses challenges in manufacturability and patient administration due to elevated solution viscosity. Often many therapeutically pot
Externí odkaz:
https://doaj.org/article/e2daa594cd5d4ef1982943739d76cbeb
Autor:
Joy Jesumeda Oladimeji, Ayodeji Abe, Pullikanti Lava Kumar, Paterne A. Agre, Oluyinka Johnson Ilesanmi, Ramesh Raju Vetukuri, Ranjana Bhattacharjee
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Genetic diversity is crucial for conservation efforts as well as breeding programs targeted at the development of improved varieties. Taro, a climate-resilient crop, plays a vital role in the nutritional and economic livelihoods o
Externí odkaz:
https://doaj.org/article/c3c894dd9d134c1b9ba2ec0ece0b0a45
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Due to its appealing qualities, such as its miniature size and the ability to modify physical properties through chemical synthesis and molecular design, polymer material offers considerable advantages over traditional inorganic material-bas
Externí odkaz:
https://doaj.org/article/77c8961119174b9da47ee5aeec3c8c9c
Publikováno v:
Journal of Multidisciplinary Healthcare, Vol Volume 17, Pp 5091-5104 (2024)
Anita Christaline Johnvictor,1 M Poonkodi,1 N Prem Sankar,1 Thinesh VS2 1School of Computer Science and Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, India; 2Arista Networks Pvt Ltd, Bangalore, IndiaCorrespondence: Anita Christal
Externí odkaz:
https://doaj.org/article/3e8b6e80cd6c40aa8e76dbe1910384ed
Autor:
Sina Abdollahi, Darius P. Schaub, Madalena Barroso, Nora C. Laubach, Wiebke Hutwelker, Ulf Panzer, S.øren W. Gersting, Stefan Bonn
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-27 (2024)
Abstract The evaluation of compound-target interactions (CTIs) is at the heart of drug discovery efforts. Given the substantial time and monetary costs of classical experimental screening, significant efforts have been dedicated to develop deep learn
Externí odkaz:
https://doaj.org/article/380b64076bc34143b62f43f36095c6fa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Because of the abundance of sodium resources, sodium-ion batteries (NIBs) offer a promising alternative electrochemical energy storage solution. One of the current roadblocks to the development of NIBs technology is a lack of electrode mater
Externí odkaz:
https://doaj.org/article/edc297ac778f4db194108aad0f3fdf8c
Autor:
I. V. Golyakova, V. А. Karpiyevich
Publikováno v:
Вестник университета, Vol 0, Iss 8, Pp 235-244 (2024)
The differences between Belarusian women’s perceptions of safety, as well as the links between these perceptions with victimization and social gender have been analyzed. The purpose of the study is to identify the peculiarities of women’s percept
Externí odkaz:
https://doaj.org/article/873f2fbec35a450d9dcc2c078f89a8b8
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract Modern laboratory medicine relies on analytical instruments for bacterial detection, focusing on biosensors and optical sensors for early disease diagnosis and treatment. Thus, Density Functional Theory (DFT) was utilized to study the reacti
Externí odkaz:
https://doaj.org/article/16e855563b1a4916b6f24a04530d9279