Short-term and Subchronic Repeated Exposure Studies with 5-Ethylidene-2-norbornene Vapor in the Rat

Autor: James C. Norris, Darol E. Dodd, Patricia E. Losco, Shirley C. Price, Paul Grasso, Dennis R. Klonne, Douglas A. Neptun, Bryan Ballantyne

Publikováno v: Journal of Applied Toxicology. 17:197-210

5-Ethylidene-2-norbornene (ENB) is an industrial chemical whose physical properties indicate a likelihood for vapor exposure to humans. The potential for target organ or cumulative toxicity was investigated in rats exposed for 6 h per day for 9 days

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ee4979935ece0696cb8ef37f6556765
https://doi.org/10.1002/(sici)1099-1263(199707)17:4<197::aid-jat429>3.0.co

Evaluation of the Developmental Toxicity of Ethylene Glycol Aerosol in CD-1 Mice by Nose-Only Exposure

Autor: Bryan Ballantyne, I. M. Pritts, R. W. Tyl, Dennis R. Klonne, Darol E. Dodd, L. C. Fisher, Patricia E. Losco, D. L. Fait

Publikováno v: Toxicological Sciences. 27:49-62

Ethylene glycol (EG; CAS No. 107-21-1) is teratogenic to mice by whole-body (WB) exposure to aerosol (1000-2500 mg/m3). The WB results were confounded by possible exposure from ingestion after grooming and/or from percutaneous absorption. Therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752bb1a0f57f517b16a37c24913770fa
https://doi.org/10.1093/toxsci/27.1.49

Acute and 2-Week Aerosol Inhalation Studies on 970 and 1700 Molecular Weight Ethylene Oxide/Propylene Oxide (EO/PO) Polymers

Autor: Dennis R. Klonne, Patricia E. Losco, Heather D. Burleigh-Flayer, T. R. Tyler, Darol E. Dodd

Publikováno v: Inhalation Toxicology. 5:189-201

Prior aerosol inhalation studies on heavier molecular weight members of this series of ethylene oxide/propylene oxide (EO/PO) polymers have demonstrated that the lung is the primary target organ in rats. These studies extended the toxicological data

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbe6ebc105ed227a743ce745ee78cbff
https://doi.org/10.3109/08958379309034501

Contributors

Autor: Husein Ajwa, Iris S. Ale, Sandra L. Allen, Judith Alsop, Gail Arce, D.J. Ashworth, Sharada Balakrishnan, John B. Barnett, Dana B. Barr, Terrell Barry, Ronald E. Baynes, Sheryl Beauvais, Karin S. Bentley, Craig E. Bernard, Nida Besbelli, Richard Billington, Ann M. Blacker, Jerry N. Blancazo, Charles B. Breckenridge, Gerald T. Brooks, James Bruckner, Kathleen M. Brundage, Quang Bui, Franca M. Buratti, James S. Bus, Geoffrey M. Calvert, Linda L. Carlock, John E. Casida, Howard W. Chambers, Janice E. Chambers, Heidi P. Chan, Graham Chester, J. Marshall Clark, Thomas Class, M. Scott Clifton, Roger Cochran, Emma Di Consiglio, Curtis C. Dary, Franck E. Dayan, Allison L. De Vries, Kelly J. Dix, Michael H. Dong, Timothy A. Dotson, John Doull, Jeffrey H. Driver, Stephen O. Duke, M. Bigelow Dyk, David A. Eastmond, David L. Eaton, Marion Ehrich, David L. Eisenbrandt, J. Charles Eldridge, Jeffrey B. Evans, Donna Farmer, Allan S. Felsot, Penelope A. Fenner-Crisp, Joan L. Fletcher, Sara Flores, Roy Fortmann, Toshio Fujita, Derek W. Gammon, Suduan Gao, V.F. Garry, Sean C. Gehen, Panos Georgopoulos, B.B. Gollapudi, Elliot B. Gordon, F. Guerino, Thomas R. Hanley, Lindsay Hanson, Paul R. Harp, Michael C. Harrass, Jane E. Harris, Wayland J. Hayes, Thomas Hertner, Frederick G. Hess, William F. Heydens, Ernest Hodgson, L. Holden, Jon A. Hotchkiss, Susan Hurt, Sastry Isukapalli, Seshadri Iyengar, Poorni Iyer, Inge M. Jensen, Russell L. Jones, Bernard S. Jortner, Hideo Kaneko, Robert J. Kavlock, Iain D. Kelly, Michael P. Kenna, Elke Kennepohl, Young Soo Keum, Jeong-Han Kim, Loreen Kleinschmidt, Dennis R. Klonne, James B. Knaak, Mike E. Krolski, Ian C. Lamb, Richard L. Lampman, Mikael Langner, Jennifer L. Lantz, Dominique Lasserre-Bigot, Edward D. Levin, Qing X. Li, Jing Liu, Edward A Lock, Marcello Lotti, Curt Lunchick, A.V. Lyubimov, Howard Maibach, Lisa E. Maier, Susan Makris, Mark J. Manning, Rex E. Marsh, Melanie Marty, Ursula May-Hertl, Thomas McCurdy, Tom McKone, Edward C. Meek, Louise N. Mehler, Gary J. Mihlan, Thomas B. Moore, Marsha K. Morgan, Ian C. Munro, Toshio Narahashi, Keiichiro Nishimura, Robert J. Novak, William J. Ntow, Michael A. O’Malley, Frederick W. Oehme, Janet Ollinger, Thomas G. Osimitz, Muhilan D. Pandian, P.P. Parsons, Merle G. Paule, Virginie Payraudeau, Erin C. Peck, Alain F. Pelfrène, Kimberly Pendino, Barbara J. Petersen, Amanda L. Piccirillo, Vincent J. Piccirillo, Joachim D. Pleil, Kathryn Ponnock, Carey Pope, Robert H. Poppenga, Su-wei Qi, Ruijun Qin, Deborah Ramsingh, Lawrence W. Reiter, Rudy J. Richardson, Leonard Ritter, Jim E. Riviere, John H. Ross, Karl K. Rozman, Andrew L. Rubin, Michael K. Rust, Luis O. Ruzo, Terrell P. Salmon, G.K. (Ghona) Sangha, James N. Seiber, Frank Selman, Larry P. Sheets, Linda S. Sheldon, Marilyn Silva, James W. Simpkins, William Slikker, Paul Slovic, Andrew G. Smith, Wayne R. Snodgrass, Jon R. Sobus, David M. Soderlund, Keith R. Solomon, Frank Spurlock, James T. Stevens, Tammy E. Stoker, W.T. Stott, Daniel L. Sudakin, Chiyozo Takayama, Emanuela Testai, Thomas Thongsinthusak, Charles Timchalk, Olga A. Timofeeva, Abraham J. Tobia, Rogelio Tornero-Velez, Nicolle S. Tulve, Matazaemon Uchida, István Ujváry, Daniel Vallero, Bennard van Ravenswaay, Felix Waechter, Edgar Weber, Ronald C. Wester, Paul Whatling, Gary K. Whitmyre, Heinrich Wicke, Sanjeeva J. Wijeyesakere, Martin F. Wilks, Alan G.E. Wilson, Barry W. Wilson, Michael D. Woodward, Jayne Wright, S.R. Yates, Masanori Yoshida, Bruce M. Young, Frank G. Zalom, Valerie Zartarian, Hongbo Zhai, Xiaofei Zhang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a870b5ec229c808850c63447b71171b2
https://doi.org/10.1016/b978-0-12-374367-1.00124-5

Evaluation of the Developmental Toxicity of Ethylene Glycol Monohexyl Ether Vapor in Fischer 344 Rats and New Zealand White Rabbits

Autor: ROCHELLE W. TYL, BRYAN BALLANTYNE, KATHRYN A. FRANCE, LOUAN C. FISHER, DENNIS R. KLONNE, IRVIN M. PRITTS

Publikováno v: Toxicological Sciences. 12:269-280

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::361f3514187cb07ca47431b0ae8c38f9
https://doi.org/10.1093/toxsci/12.2.269