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248-OR: MiTy Kids: Follow-Up of Offspring Exposed to Metformin In-Utero in Mothers with Type 2 Diabetes in the MiTy Trial

Autor: DENICE FEIG, J. JOHANNA SANCHEZ, KELLIE MURPHY, ELIZABETH ASZTALOS, BERNARD ZINMAN, DAVID SIMMONS, ANDREA HAQQ, IVAN G. FANTUS, LORRAINE LIPSCOMBE, ANTHONY ARMSON, JON F.R. BARRETT, LOIS E. DONOVAN, PAUL KARANICOLAS, GAIL KLEIN, SIOBHAN TOBIN, KATHRYN MANGOFF, GEORGE TOMLINSON, JILL HAMILTON

Publikováno v: Diabetes. 71

Background: Offspring of mothers with T2D are at increased risk of obesity and diabetes. In the MiTy trial [pregnant T2D randomized to metformin vs. placebo], infants exposed to metformin were lighter, had lower fat-mass and risk of large-for-gestati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39184033999e6b7df531e7374002e2d0
https://doi.org/10.2337/db22-248-or

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253-OR: Maternal Hyperglycemia Is Associated with Offspring Adiposity through Altered Lipid Metabolism in Type 1 Diabetes Pregnancy

Autor: CLAIRE L. MEEK, ZOE A. STEWART, DENICE FEIG, ALBERT KOULMAN, HELEN R. MURPHY

Publikováno v: Diabetes. 71

Objective: Type 1 diabetes in pregnancy is associated with increased birthweight and adiposity in offspring, which may contribute to increased future cardiometabolic risk. We assessed if the effects of maternal hyperglycemia on adiposity were mediate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e725399b85657e2bdee78cd72f414dc8
https://doi.org/10.2337/db22-253-or

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249-OR: Growth Trajectories of MiTy Kids' Offspring According to Intrauterine Growth Status

Autor: J. JOHANNA SANCHEZ, JILL HAMILTON, GEORGE TOMLINSON, ELIZABETH ASZTALOS, KELLIE MURPHY, BERNARD ZINMAN, DAVID SIMMONS, ANDREA HAQQ, IVAN G. FANTUS, LORRAINE LIPSCOMBE, ANTHONY ARMSON, JON F.R. BARRETT, LOIS E. DONOVAN, PAUL KARANICOLAS, YIDI JIANG, SIOBHAN TOBIN, KATHRYN MANGOFF, GAIL KLEIN, DENICE FEIG

Publikováno v: Diabetes. 71

Background: In the MiTy trial [pregnant T2D randomized to metformin vs. placebo], infants exposed to metformin in-utero had a lower risk of large-for-gestational-age (LGA) but were at higher risk of small-for-gestational-age (SGA) . To date, there ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c2a15445b6996c0acb26ff9d06e1dd7
https://doi.org/10.2337/db22-249-or

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399-P: Associations among Biomarkers of Inflammation, Tubular Injury, and Lipid Metabolism with Gestational Diabetes Mellitus (GDM) Status, Microalbuminuria, and Retinopathy in the MARIGOLD Study

Autor: HONGYAN LIU, VIKAS S. SRIDHAR, LEIF ERIK LOVBLOM, DENICE FEIG, ELAINE HERER, ALEX KISS, LORRAINE LIPSCOMBE, PAUL M. YIP, DAVID CHERNEY, BAIJU R. SHAH

Publikováno v: Diabetes. 71

Levels of hyperglycemia below those for diagnosis of diabetes are associated with microvascular injury, though the duration required to induce these complications remains poorly understood. This is especially relevant in patients with GDM due to its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e6960707a352e461ecd30007a347e17
https://doi.org/10.2337/db22-399-p

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1064-P: Use of the inControl Algorithm for Automated Insulin Delivery during Childbirth: A Case Series

Autor: LOIS E. DONOVAN, JULIE MCKEEN, DENICE FEIG

Publikováno v: Diabetes. 71

Background: Automated Insulin Delivery systems (AIDs) can improve glucose control in people with type 1 diabetes but study of their use during childbirth is limited. Some commercially available AIDs use the inControl algorithm (iCa) to automate insul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8460955056b05602b67c55becb041f3a
https://doi.org/10.2337/db22-1064-p

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277-OR: Use of Noncarbohydrate Fuels Is Associated with Materno-Fetal Complications in Type 1 Diabetes Pregnancy: Metabolomics Analysis of the CONCEPTT Trial

Autor: Helen R. Murphy, Zoe A. Stewart, Denice Feig, Jennifer M. Yamamoto, Claire L. Meek, Albert Koulman, Samuel Furse

Publikováno v: Diabetes. 70

Aims: We assessed metabolomic signatures in maternal and cord blood associated with suboptimal outcomes in the continuous glucose monitoring in women with type 1 diabetes in pregnancy trial (CONCEPTT). Methods: Serum samples from 162 mothers (12, 24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1eea12dc0ef18d2015cb21c7a2c0f52
https://doi.org/10.2337/db21-277-or

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194-OR: Impaired Awareness of Hypoglycemia and Maternal/Neonatal Outcomes in the CONCEPTT Trial

Autor: Denice Feig, Helen R. Murphy, Jasmine Bahrami, George Tomlinson

Publikováno v: Diabetes. 69

Background: Patients with diabetes and impaired awareness of hypoglycemia (IAH) are at increased risk of severe hypoglycemia (SH). IAH is increased during pregnancy. To date, maternal and neonatal outcomes of pregnant women with hypoglycemia unawaren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5081144020f2ca1b4aea9a5c5ba700c
https://doi.org/10.2337/db20-194-or

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351-OR: Continuous Glucose Monitoring in Pregnant Women with Type 1 Diabetes: Cost-Effectiveness Analyses of the CONCEPTT Randomized Controlled Trial

Autor: Denice Feig, Nashita Patel, Helen R. Murphy

Publikováno v: Diabetes. 68

Aims: To evaluate the cost-effectiveness of continuous glucose monitoring (CGM) in type 1 diabetes (T1D) pregnancy. Methods: Decision analytical models to compare T1D antenatal care with and without use of CGM. Probabilities, maternal health state ut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff6f47ea4a4aca414dd3e1dc04afae20
https://doi.org/10.2337/db19-351-or

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