Zobrazeno 1 - 9
of 9
pro vyhledávání: '"DEHAN CAI"'
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-28 (2022)
Abstract Viruses change constantly during replication, leading to high intra-species diversity. Although many changes are neutral or deleterious, some can confer on the virus different biological properties such as better adaptability. In addition, v
Externí odkaz:
https://doaj.org/article/80868df30d5d476e92a2686323d8379b
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Evidences increasingly indicate the involvement of gene network rewiring in disease development and cell differentiation. With the accumulation of high-throughput gene expression data, it is now possible to infer the changes of gene networks between
Externí odkaz:
https://doaj.org/article/22efb4edfdb342bf8f2d7afead8c5f07
Publikováno v:
Bioinformatics. 38:5360-5367
MotivationLacking strict proofreading mechanisms, many RNA viruses can generate progeny with slightly changed genomes. Being able to characterize highly similar genomes (i.e. haplotypes) in one virus population helps study the viruses’ evolution an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a5c5c5fad64b74cc6f6d25ad7c56d9
https://doi.org/10.1093/bioinformatics/btac708
https://doi.org/10.1093/bioinformatics/btac708
Publikováno v:
Bioinformatics (Oxford, England).
MotivationRNA viruses tend to mutate constantly. While many of the variants are neutral, some can lead to higher transmissibility or virulence. Accurate assembly of complete viral genomes enables the identification of underlying variants, which are e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4754225b8efe3ee3f81c20677733a7
https://pubmed.ncbi.nlm.nih.gov/36571490
https://pubmed.ncbi.nlm.nih.gov/36571490
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics, Vol 12 (2021)
Evidences increasingly indicate the involvement of gene network rewiring in disease development and cell differentiation. With the accumulation of high-throughput gene expression data, it is now possible to infer the changes of gene networks between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f4c6c64bdfb667cabe1212df8bff0c
http://europepmc.org/articles/PMC8632038
http://europepmc.org/articles/PMC8632038
Publikováno v:
Bioinformatics (Oxford, England).
Motivation Most RNA viruses lack strict proofreading during replication. Coupled with a high replication rate, some RNA viruses can form a virus population containing a group of genetically related but different haplotypes. Characterizing the haploty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6a650fb9a9fd2a326bb8e2955dbae7
https://pubmed.ncbi.nlm.nih.gov/35157018
https://pubmed.ncbi.nlm.nih.gov/35157018
Publikováno v:
Bioinformatics; Jan2023, Vol. 39 Issue 1, p1-8, 8p, 5 Diagrams, 3 Charts, 2 Graphs
Publikováno v:
Briefings in bioinformatics. 22(6)
The mechanisms controlling biological process, such as the development of disease or cell differentiation, can be investigated by examining changes in the networks of gene dependencies between states in the process. High-throughput experimental metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ac10d8ec2a957db1279f1baf4534ce
https://pubmed.ncbi.nlm.nih.gov/33975339
https://pubmed.ncbi.nlm.nih.gov/33975339
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-28 (2022)
Genome Biology
Genome Biology
Genome epidemiology, which uses genomic data to analyze the source and spread of infectious diseases, provides important information beyond interview-based methods. Given fast accumulation of sequenced viral genomes, a basic need in genome epidemiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ab04052f262433e18bc869bb89064a
https://doi.org/10.1101/2020.12.21.423722
https://doi.org/10.1101/2020.12.21.423722
