Potent and Selective Ketoamide-Based Inhibitors of Cysteine Protease, Cathepsin K

Autor: Tavares, F. X., Deaton, D. N., Miller, A. B., Miller, L. R., Wright, L. L., Zhou, H.-Q.

Publikováno v: Journal of Medicinal Chemistry; October 2004, Vol. 47 Issue: 21 p5049-5056, 8p

Synthesis and Evaluation of Potent and Selective β3 Adrenergic Receptor Agonists Containing Acylsulfonamide, Sulfonylsulfonamide, and Sulfonylurea Carboxylic Acid Isosteres

Autor: Uehling, D. E., Donaldson, K. H., Deaton, D. N., Hyman, C. E., Sugg, E. E., Barrett, D. G., Hughes, R. G., Reitter, B., Adkison, K. K., Lancaster, M. E., Lee, F., Hart, R., Paulik, M. A., Sherman, B. W., True, T., Cowan, C.

Publikováno v: Journal of Medicinal Chemistry; January 2002, Vol. 45 Issue: 3 p567-583, 17p

Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties.

Autor: Bredael, Kato¹ (AUTHOR), Geurs, Silke^1,2 (AUTHOR), Clarisse, Dorien² (AUTHOR), De Bosscher, Karolien² (AUTHOR), D'hooghe, Matthias¹ (AUTHOR)

Publikováno v: Journal of Chemistry. 5/19/2022, p1-21. 21p.

Enhanced Hemodynamics of Anisometric TPMS Topology Reduce Blood Clotting in 3D Printed Blood Contactors.

Autor: Hirschwald LT; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany., Hagemann F; DWI - Leibniz-Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany., Biermann M; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany., Hanßen P; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany., Hoffmann P; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany., Höhs T; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany., Neuhaus F; DWI - Leibniz-Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany., Tillmann MT; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany., Peric P; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany., Wattenberg M; Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering, Mönkhofer Weg 239a, 23562, Lübeck, Germany., Stille M; Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering, Mönkhofer Weg 239a, 23562, Lübeck, Germany., Fechter T; Department of Anesthesiology, University Hospital Aachen, Pauwelsstr. 30, 52074, Aachen, Germany., Theißen A; Department of Anesthesiology, University Hospital Aachen, Pauwelsstr. 30, 52074, Aachen, Germany., Winnersbach P; Department of Anesthesiology, University Hospital Aachen, Pauwelsstr. 30, 52074, Aachen, Germany., Barbian KP; Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, RWTH Aachen University, Forckenbeckstr. 55, 52074, Aachen, Germany., Jansen SV; Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, RWTH Aachen University, Forckenbeckstr. 55, 52074, Aachen, Germany., Steinseifer U; Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, RWTH Aachen University, Forckenbeckstr. 55, 52074, Aachen, Germany., Wiegmann B; Department for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.; Implant Research and Development (NIFE), Lower Saxony Centre for Biomedical Engineering, Stadtfelddamm 34, 30625, Hannover, Germany.; German Center for Lung Research (DZL), Carl-Neuberg-Str. 1, 30625, Hannover, Germany., Rossaint R; Department of Anesthesiology, University Hospital Aachen, Pauwelsstr. 30, 52074, Aachen, Germany., Wessling M; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany.; DWI - Leibniz-Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany., Bleilevens C; Department of Anesthesiology, University Hospital Aachen, Pauwelsstr. 30, 52074, Aachen, Germany., Linkhorst J; Chemical Process Engineering (AVT.CVT), RWTH Aachen University, Forckenbeckstr. 51, 52074, Aachen, Germany.; Process Engineering of Electrochemical Systems, Department of Mechanical Engineering, Technical University of Darmstadt, Otto-Berndt-Straße 2, 64287, Darmstadt, Germany.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2024 Nov 15, pp. e2403111. Date of Electronic Publication: 2024 Nov 15.

Bile salt signaling and bile salt-based therapies in cardiometabolic disease.

Autor: Groenen, Claire C. J., Thuc-Anh Nguyen, Paulusma, Coen C., de Graaf, Stan F. J. van

Publikováno v: Clinical Science; Jan2024, Vol. 138 Issue 1, p1-21, 21p