Zobrazeno 1 - 10
of 50
pro vyhledávání: '"DE-SHIEN JONG"'
Autor:
Yovita Permata Budi, Yi-Hsuan Li, Chien Huang, Mu-En Wang, Yi-Chun Lin, De-Shien Jong, Chih-Hsien Chiu, Yi-Fan Jiang
Publikováno v:
PeerJ, Vol 10, p e13867 (2022)
Aims Studies have observed changes in autophagic flux in the adipose tissue of type 2 diabetes patients with obesity. However, the role of autophagy in obesity-induced insulin resistance is unclear. We propose to confirm the effect of a high-fat diet
Externí odkaz:
https://doaj.org/article/ab11d8f805704d77bcc9261726d3aeee
Autor:
Chien Huang, Hsiu-Ju Hsu, Mu-En Wang, Meng-Chieh Hsu, Leang-Shin Wu, De-Shien Jong, Yi-Fan Jiang, Chih-Hsien Chiu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Obese men have lower circulating testosterone than men with an optimal body mass index. Elevated fatty acids (FAs) caused by obesity have been reported to suppress the steroidogenesis of Leydig cells. Recent studies have demonstrated that au
Externí odkaz:
https://doaj.org/article/24d0e010c09141a29b1452dd5e161be8
Autor:
Mu-En Wang, Brijesh K. Singh, Meng-Chieh Hsu, Chien Huang, Paul M. Yen, Leang-Shin Wu, De-Shien Jong, Chih-Hsien Chiu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Previous studies have demonstrated that saturated fatty acids (SFAs) are more lipotoxic than unsaturated fatty acids (UFAs) in inhibiting hepatic autophagy and promoting non-alcoholic steatohepatitis (NASH). However, there have been few stud
Externí odkaz:
https://doaj.org/article/c6edea5ff3c74a4da44c0abc0815201a
Autor:
Hsin Yi Chiu, Chia Sheng Chang, Ya Yun Chien, Leang-Shin Wu, De-Shien Jong, Chi Ming Chiang, Chih-Hsien Chiu
Publikováno v:
Journal of the Chinese Medical Association. 84:389-399
BACKGROUND Kisspeptin (KISS1) and kisspeptin receptor (KISS1R) are essential gatekeepers of the reproductive system. The functions of KISS1 and KISS1R in corpus luteal cells remain ambiguous. The objective was to observe normal physiologic functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7434197d95916ac676324e14b09ba7d6
https://doi.org/10.1097/jcma.0000000000000508
https://doi.org/10.1097/jcma.0000000000000508
Publikováno v:
Reproduction. 160:843-852
Kisspeptin and its receptor KISS1R have been proven as pivotal regulators on controlling the hypothalamus–pituitary–gonad axis. Inactivating mutations in one of them cause idiopathic hypogonadotropic hypogonadism in human as well as rodent models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985942f6d1318b113d508a57cc2b1977
https://doi.org/10.1530/rep-20-0328
https://doi.org/10.1530/rep-20-0328
Autor:
Leang-Shin Wu, Meng-Chieh Hsu, Yi-Fan Jiang, Mu-En Wang, Chih-Hsien Chiu, Hsiu-Ju Hsu, De-Shien Jong, Chien Huang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Obese men have lower circulating testosterone than men with an optimal body mass index. Elevated fatty acids (FAs) caused by obesity have been reported to suppress the steroidogenesis of Leydig cells. Recent studies have demonstrated that autophagy r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9d6991f22353e3120eaa4795dee2c4
http://europepmc.org/articles/PMC8206377
http://europepmc.org/articles/PMC8206377
Publikováno v:
Journal of the Chinese Medical Association : JCMA. 84(2)
BACKGROUND Kisspeptin and its receptor KISS1R have been found to be essential regulators of reproductive function. Previous data have revealed the presence of Kiss1 and Kiss1r mRNAs in the hypothalamus and the testis of humans and rodents. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f5e9fc93e81e893183460e4168fbc1
https://pubmed.ncbi.nlm.nih.gov/33901124
https://pubmed.ncbi.nlm.nih.gov/33901124
Autor:
Budi, Yovita Permata, Yi-Hsuan Li, Chien Huang, Mu-En Wang, Yi-Chun Lin, De-Shien Jong, Chih-Hsien Chiu, Yi-Fan Jiang
Publikováno v:
PeerJ; Aug2022, p1-19, 19p
Autor:
Leang-Shin Wu, Yi-Hsieng Samuel Wu, Yi-Fan Jiang, Hao-Yi Wang, Chien Huang, Chih-Hsien Chiu, Mu-En Wang, Meng-Chieh Hsu, De-Shien Jong
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Previous studies have demonstrated the important role of kisspeptin in impaired glucose-stimulated insulin secretion (GSIS). In addition, it was reported that the activation of autophagy in pancreatic β-cells decreases insulin secretion by selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948560c2c9b83211d3d7e65eaf3839c3
http://europepmc.org/articles/PMC6877614
http://europepmc.org/articles/PMC6877614
Autor:
Hsin-Yi, Chiu, Chi-Ming, Chiang, Szu-Peng, Yeh, De-Shien, Jong, Leang-Shin, Wu, Hung-Chang, Liu, Chih-Hsien, Chiu
Publikováno v:
Oncology Letters
Patients with lung cancer harboring activating epidermal growth factor (EGFR) mutations and pre-existing diabetes have been demonstrated to exhibit poor responses to first-line EGFR-tyrosine kinase inhibitor (TKI) therapy. Strategies for the manageme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa60175c843502fb0b9caa001269a89e
https://pubmed.ncbi.nlm.nih.gov/32963612
https://pubmed.ncbi.nlm.nih.gov/32963612