Inhibition of platelet function by cis-unsaturated fatty acids

Autor: DE MacIntyre, RL Hoover, M Smith, M Steer, C Lynch, MJ Karnovsky, EW Salzman

Publikováno v: Blood. 63:848-857

The uptake of free fatty acids has previously been shown to affect the capping of lymphocytes, and there is evidence that different types of fatty acids may partition into separate lipid domains in cell surface membranes. In studies of gel-filtered h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eda4a4b53b1e5461b65e89adb2a790eb
https://doi.org/10.1182/blood.v63.4.848.bloodjournal634848

Population-based interventions for preventing falls and fall-related injuries in older people.

Autor: Lewis SR; Bone and Joint Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., McGarrigle L; School of Health Sciences, Division of Nursing, Midwifery and Social Work, The University of Manchester, and Manchester Academic Health Science Centre, Manchester, UK., Pritchard MW; Bone and Joint Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Bosco A; NIHR Applied Research Collaboration Greater Manchester, School of Health Sciences, The University of Manchester, and Manchester Academic Health Science Centre, Manchester, UK., Yang Y; NIHR Applied Research Collaboration Greater Manchester, School of Health Sciences, The University of Manchester, and Manchester Academic Health Science Centre, Manchester, UK., Gluchowski A; NIHR Applied Research Collaboration Greater Manchester, School of Health Sciences, The University of Manchester, and Manchester Academic Health Science Centre, Manchester, UK.; School of Health & Society, University of Salford, Salford, UK., Sremanakova J; School of Health Sciences, Division of Nursing, Midwifery and Social Work, The University of Manchester, and Manchester Academic Health Science Centre, Manchester, UK., Boulton ER; School of Health Sciences, Division of Nursing, Midwifery and Social Work, The University of Manchester, and Manchester Academic Health Science Centre, Manchester, UK., Gittins M; Division of Population Health, Health Services Research & Primary Care, School of Health Sciences, The University of Manchester, Manchester, UK., Spinks A; School of Population Health, University of Queensland, Queensland, Australia., Rapp K; Department of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany., MacIntyre DE; Public Health, West Sussex County Council, Chichester, UK., McClure RJ; Health Decision Support Pty Ltd, Armidale, NSW, Australia., Todd C; NIHR Applied Research Collaboration Greater Manchester, School of Health Sciences, The University of Manchester, and Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, UK.

Publikováno v: The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2024 Jan 05; Vol. 1. Cochrane AN: CD013789. Date of Electronic Publication: 2024 Jan 05.

Identification and Characterization of GAL-021 as a Novel Breathing Control Modulator.

Autor: Golder FJ; From the Department of Drug Discovery, Galleon Pharmaceuticals, Inc., Horsham, Pennsylvania (F.J.G., S.D., S.M.B., R.G., C.I., A.K., S.P., V.P., D.R., R.W., J.C.M., D.E.M.); Department of Physiology, University of Pennsylvania, Philadelphia, Pennsylvania (T.H.); and Department of Physiology, Brody School of Medicine, East Carolina University, Greenville, North Carolina (R.L.W., M.R.V.S.)., Dax S, Baby SM, Gruber R, Hoshi T, Ideo C, Kennedy A, Peng S, Puskovic V, Ritchie D, Woodward R, Wardle RL, Van Scott MR, Mannion JC, MacIntyre DE

Publikováno v: Anesthesiology [Anesthesiology] 2015 Nov; Vol. 123 (5), pp. 1093-104.

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.

Autor: Hong Q; Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065-0900, USA. Qingmei_hong@merck.com, Bakshi RK, Palucki BL, Park MK, Ye Z, He S, Pollard PG, Sebhat IK, Liu J, Guo L, Cashen DE, Martin WJ, Weinberg DH, MacNeil T, Tang R, Tamvakopoulos C, Peng Q, Miller RR, Stearns RA, Chen HY, Chen AS, Strack AM, Fong TM, MacIntyre DE, Wyvratt MJ, Nargund RP

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2011 Apr 15; Vol. 21 (8), pp. 2330-4. Date of Electronic Publication: 2011 Mar 01.

1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.

Autor: Anandan SK; Arête Therapeutics, Inc., 7000 Shoreline Court, South San Francisco, CA 94080, United States. anandan30@yahoo.com, Webb HK, Chen D, Wang YX, Aavula BR, Cases S, Cheng Y, Do ZN, Mehra U, Tran V, Vincelette J, Waszczuk J, White K, Wong KR, Zhang LN, Jones PD, Hammock BD, Patel DV, Whitcomb R, MacIntyre DE, Sabry J, Gless R

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2011 Feb 01; Vol. 21 (3), pp. 983-8. Date of Electronic Publication: 2010 Dec 13.