Summation of activation at the branch-stem transition of Mimosa pudica; a comparison with summation in cardiac tissue.

Autor: de Bakker, Jacques M. T.¹ (AUTHOR) j.m.debakker@amsterdamumc.nl, Coronel, Ruben¹ (AUTHOR)

Publikováno v: PLoS ONE. 5/19/2023, Vol. 17 Issue 5, p1-18. 18p.

Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice

Autor: Jansen, John A., Noorman, Maartje, Musa, Hassan, Stein, Mèra, de Jong, Sanne, van der Nagel, Roel, Hund, Thomas J., Mohler, Peter J., Vos, Marc A., van Veen, Toon A., de Bakker, Jacques M., Delmar, Mario, van Rijen, Harold V.

Publikováno v: In Heart Rhythm April 2012 9(4):600-607

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Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia

Autor: Bossu, Alexandre, Houtman, Marien J C, Meijborg, Veronique M F, Varkevisser, Rosanne, Beekman, Henriette D M, Dunnink, Albert, de Bakker, Jacques M T, Mollova, Nevena, Rajamani, Sridharan, Belardinelli, Luiz, van der Heyden, Marcel A G, Vos, Marc A

Publikováno v: British Journal of Pharmacology, 175(12), 2470. Wiley-Blackwell
British Journal of Pharmacology
British journal of pharmacology, 175(12), 2470-2482. Wiley-Blackwell

BACKGROUND AND PURPOSE: Enhanced late sodium current (late INa ) in heart failure and long QT syndrome type 3 is proarrhythmic. This study investigated the antiarrhythmic effect and mode of action of the selective and potent late INa inhibitor GS-458

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::26a47f20c7cb87991d145cdaf5e8b92d
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85046451295&origin=inward

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