Zobrazeno 1 - 6
of 6
pro vyhledávání: '"DDM, dodecylmaltoside"'
Publikováno v:
The Journal of Biological Chemistry
Members of the metallo-β-lactamase (MBL) superfamily of enzymes harbor a highly conserved αββα MBL-fold domain and were first described as inactivators of common β-lactam antibiotics. In humans, these enzymes have been shown to exhibit diverse
Autor:
Michelle Clare, Alice Rothnie, Heike Böning, Thomas Krey, Roslyn M. Bill, Ivana Milic, Andrew Devitt, Nikola Paul Chmel, Hoor Ayub
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes
Tetraspanins exert a wide range of cellular functions of broad medical importance. Despite this, their biophysical characteristics are incompletely understood. Only two high-resolution structures of full-length tetraspanins have been solved. One is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d7f926a89bb5fd1e830f119b5c65a1
https://publications.aston.ac.uk/id/eprint/41776/1/1_s2.0_S0005273620302625_main.pdf
https://publications.aston.ac.uk/id/eprint/41776/1/1_s2.0_S0005273620302625_main.pdf
Autor:
Carolina, Hierro-Yap, Karolína, Šubrtová, Ondřej, Gahura, Brian, Panicucci, Caroline, Dewar, Christos, Chinopoulos, Achim, Schnaufer, Alena, Zíková
Publikováno v:
The Journal of Biological Chemistry
Mitochondrial ATP synthase is a reversible nanomotor synthesizing or hydrolyzing ATP depending on the potential across the membrane in which it is embedded. In the unicellular parasite Trypanosoma brucei, the direction of the complex depends on the l
Autor:
Melissa Morrison, Raelynn Brassard, Zhenze Jiang, Verena Siebert, Anthony J. O’Donoghue, Elena Arutyunova, Howard S. Young, Marius K. Lemberg, Emmanuella Takyi, Laine Lysyk, M. Joanne Lemieux
Publikováno v:
The Journal of Biological Chemistry
The rhomboid protease PARL is a critical regulator of mitochondrial homeostasis through its cleavage of substrates such as PINK1, PGAM5, and Smac/Diablo, which have crucial roles in mitochondrial quality control and apoptosis. However, the catalytic
Autor:
James Kean, Clair Baldock, Robert C. Ford, Robert M. Cleverley, Chitra A. Shintre, Jeremy P. Derrick, Stephen M. Prince
Publikováno v:
Cleverley, R M, Kean, J, Shintre, C A, Baldock, C, Derrick, J P, Ford, R C & Prince, S M 2015, ' The Cryo-EM Structure of the CorA channel from Methanocaldococcus jannaschii in low magnesium conditions. ', Biochimica et Biophysica Acta. Biomembranes, vol. 1848, no. 10 Pt A, pp. 2206-2215 . https://doi.org/10.1016/j.bbamem.2015.06.002
Biochimica et Biophysica Acta
Biochimica et Biophysica Acta
CorA channels are responsible for the uptake of essential magnesium ions by bacteria. X-ray crystal structures have been resolved for two full-length CorA channels, each in a non-conducting state with magnesium ions bound to the protein: These struct
Publikováno v:
Biochemical Journal
QSOX1 (quiescin sulfhydryl oxidase 1) efficiently catalyses the insertion of disulfide bonds into a wide range of proteins. The enzyme is mechanistically well characterized, but its subcellular location and the identity of its protein substrates rema