Blood cell dynamics in P-selectin-deficient mice

Autor: RC Johnson, TN Mayadas, PS Frenette, RE Mebius, M Subramaniam, A Lacasce, RO Hynes, DD Wagner

Publikováno v: Blood. 86(3)

P-selectin is expressed on the surfaces of activated platelets and endothelium where it mediates binding to leukocytes. P-selectin- deficient mice were shown to exhibit peripheral neutrophilia (Mayadas et al: Cell 74:541, 1993). We now show that this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7405cf21c84d721de37d68ee695a9e29
https://pubmed.ncbi.nlm.nih.gov/7542495

von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively

Autor: LA Sporn, VJ Marder, DD Wagner

Publikováno v: Blood. 69(5)

Large multimers of von Willebrand factor (vWf) are released from the Weibel-Palade bodies of cultured endothelial cells following treatment with a secretagogue (Sporn et al, Cell 46:185, 1986). These multimers were shown by immunofluorescent staining

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de314cbd399df6a1de2d9f62ffc56529
https://pubmed.ncbi.nlm.nih.gov/3105624

Sequence-matching adapter trimmers generate consistent quality and assembly metrics for Illumina sequencing of RNA viruses.

Autor: Nabakooza G; Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, Tennessee, United States, assigned to Centers for Disease Control and Prevention, Atlanta, GA, USA. sxv8@cdc.gov.; Eagle Global Scientific LLC, contracting agency to the Centers for Disease Control and Prevention, Atlanta, GA, USA. sxv8@cdc.gov., Wagner DD; Eagle Global Scientific LLC, contracting agency to the Centers for Disease Control and Prevention, Atlanta, GA, USA., Momin N; Eagle Global Scientific LLC, contracting agency to the Centers for Disease Control and Prevention, Atlanta, GA, USA., Marine RL; Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA., Weldon WC; Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA., Oberste MS; Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Publikováno v: BMC research notes [BMC Res Notes] 2024 Oct 14; Vol. 17 (1), pp. 308. Date of Electronic Publication: 2024 Oct 14.

Neutrophil NLRP3 promotes cardiac injury following acute myocardial infarction through IL-1β production, VWF release and NET deposition in the myocardium.

Autor: Heger LA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.; Departement of Cardiology and Angiology, University Hospital Freiburg Bad Krozingen, 79106, Freiburg, Germany., Schommer N; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA.; Departement of Cardiology and Angiology, University Hospital Freiburg Bad Krozingen, 79106, Freiburg, Germany., Van Bruggen S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA.; Center of Molecular and Vascular Biology, Department of Cardiovascular Science, KU Leuven, 3000, Leuven, Belgium., Sheehy CE; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA., Chan W; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA., Wagner DD; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA. denisa.wagner@childrens.harvard.edu.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA. denisa.wagner@childrens.harvard.edu.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA. denisa.wagner@childrens.harvard.edu.

Publikováno v: Scientific reports [Sci Rep] 2024 Jun 24; Vol. 14 (1), pp. 14524. Date of Electronic Publication: 2024 Jun 24.

Neutrophil peptidylarginine deiminase 4 plays a systemic role in obesity-induced chronic inflammation in mice.

Autor: Van Bruggen S; Center for Vascular and Molecular Biology, Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, Leuven, Belgium; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, Massachusetts, USA. Electronic address: http://www.twitter.com/Cardio_KULeuven., Sheehy CE; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, Massachusetts, USA., Kraisin S; Center for Vascular and Molecular Biology, Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, Leuven, Belgium. Electronic address: http://www.twitter.com/Cardio_KULeuven., Frederix L; Center for Vascular and Molecular Biology, Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, Leuven, Belgium. Electronic address: http://www.twitter.com/Cardio_KULeuven., Wagner DD; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, Massachusetts, USA; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA; Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts, USA. Electronic address: denisa.wagner@childrens.harvard.edu., Martinod K; Center for Vascular and Molecular Biology, Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, Leuven, Belgium. Electronic address: Kim.martinod@kuleuven.be.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 May; Vol. 22 (5), pp. 1496-1509. Date of Electronic Publication: 2024 Feb 05.