Perspectives on in silico bone mechanobio

Autor: D Boaretti, E Wehrle, YD Bansod, DC Tourolle né Betts, R Müller

Publikováno v: European Cells & Materials, Vol 44, Pp 56-73 (2022)

Bone mechanobiology is the study of the physical, biological and mechanical processes that continuously affect the multiscale multicellular system of the bone from the organ to the molecular scale. Current knowledge derives from experimental studies,

Externí odkaz: https://doaj.org/article/57425984c5724979b3c206740fc8b167

Individualized cyclic mechanical loading improves callus properties during the remodelling phase of fracture healing in mice as assessed from time-lapsed in vivo imaging.

Autor: Wehrle E; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland. esther.wehrle@hest.ethz.ch., Paul GR; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Tourolle Né Betts DC; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Kuhn GA; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Müller R; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland. ram@ethz.ch.

Publikováno v: Scientific reports [Sci Rep] 2021 Nov 29; Vol. 11 (1), pp. 23037. Date of Electronic Publication: 2021 Nov 29.

Spatio-temporal characterization of fracture healing patterns and assessment of biomaterials by time-lapsed in vivo micro-computed tomography.

Autor: Wehrle E; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Tourolle Né Betts DC; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Kuhn GA; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Floreani E; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Nambiar MH; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Schroeder BJ; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland., Hofmann S; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland.; Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven, The Netherlands., Müller R; Institute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, 8093, Zurich, Switzerland. ram@ethz.ch.

Publikováno v: Scientific reports [Sci Rep] 2021 Apr 21; Vol. 11 (1), pp. 8660. Date of Electronic Publication: 2021 Apr 21.

Evaluation of longitudinal time-lapsed in vivo micro-CT for monitoring fracture healing in mouse femur defect models.

Autor: Wehrle E; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland., Tourolle Né Betts DC; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland., Kuhn GA; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland., Scheuren AC; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland., Hofmann S; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.; Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands., Müller R; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland. ram@ethz.ch.

Publikováno v: Scientific reports [Sci Rep] 2019 Nov 25; Vol. 9 (1), pp. 17445. Date of Electronic Publication: 2019 Nov 25.