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A comparative study of the phenotype with kainic acid-induced seizure in DBA/2 mice from three different sources

Autor: Kyung-Ku Kang, Young-In Kim, Min-Soo Seo, Soo-Eun Sung, Joo-Hee Choi, Sijoon Lee, Young-Suk Jung, Joon Young Cho, Dae Youn Hwang, Sang-Joon Park, Kil Soo Kim

Publikováno v: Laboratory Animal Research, Vol 36, Iss 1, Pp 1-7 (2020)

Abstract The kainic acid-induced seizure mouse model is widely used in epilepsy research. In this study, we applied kainic acid to the subcutaneous injections of three different sources of DBA/2 mice to compare and evaluate the seizure response. The

Externí odkaz: https://doaj.org/article/8c5a606148344309823cf3d35f20d308

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Akademický článek

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Akademický článek

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A comparative study of the phenotype with kainic acid-induced seizure in DBA/2 mice from three different sources

Autor: Joon Young Cho, Kil Soo Kim, Soo-Eun Sung, Young-Suk Jung, Joo-Hee Choi, Kyung-Ku Kang, Young-In Kim, Dae Youn Hwang, Sang-Joon Park, Sijoon Lee, Min-Soo Seo

Publikováno v: Laboratory Animal Research
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-7 (2020)

The kainic acid-induced seizure mouse model is widely used in epilepsy research. In this study, we applied kainic acid to the subcutaneous injections of three different sources of DBA/2 mice to compare and evaluate the seizure response. The three mou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79778d3c0ee1dcc13f038dc93356cf6b
http://europepmc.org/articles/PMC7594308

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Behavioral and Metabolome Differences between C57BL/6 and DBA/2 Mouse Strains: Implications for Their Use as Models for Depression- and Anxiety-Like Phenotypes

Autor: Michaela D. Filiou, Markus Nussbaumer, Christoph W. Turck, Larysa Teplytska

Publikováno v: Metabolites
Volume 11
Issue 2
Metabolites, Vol 11, Iss 128, p 128 (2021)

Mouse models are widely used to study behavioral phenotypes related to neuropsychiatric disorders. However, different mouse strains vary in their inherent behavioral and molecular characteristics, which needs to be taken into account depending on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59190190fe914077185fff3e1f3b8c0b
https://pubmed.ncbi.nlm.nih.gov/33672326

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Th 17 Cells and Nesfatin-1 are associated with Spontaneous Abortion in the CBA/j × DBA/2 Mouse Model

Autor: Heejeong Kim, Hyunwon Yang, Yiwa Chung, Eunji Im, Philjae Kim

Publikováno v: Development & Reproduction

The pregnancy and abortion process involves a complex mechanism with various immune cells present in the implantation sites and several hormones associated with pregnancy, such as leptin, ghrelin and nesfatin-1. However, the mechanism underlying spon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3812bdcc7e0c3c761db49628c789782c
https://doi.org/10.12717/dr.2015.19.4.243

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Akademický článek

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Segregation of a Spontaneous Klrd1 (CD94) Mutation in DBA/2 Mouse Substrains

Autor: Ashutosh K. Pandey, Klaus Schughart, Megan K. Mulligan, Robert Geffers, Dai Lun Shin, Esther Wilk, Jesse D. Ziebarth, Robert W. Williams, Bastian Hatesuer

Publikováno v: G3: Genes|Genomes|Genetics

Current model DBA/2J (D2J) mice lack CD94 expression due to a deletion spanning the last coding exon of the Klrd1 gene that occurred in the mid- to late 1980s. In contrast, DBA/2JRj (D2Rj) mice, crosses derived from DBA/2J before 1984, and C57BL/6J (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38af29467cf98f6b14dfc71e5983c76
http://europepmc.org/articles/PMC4321031

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Abstract 550: TFEB Expression, Turnover, and Nuclear Localization are Altered in DBA/2 Mouse Macrophages Associated With Impaired Autolysosome Formation and Lipid Droplet Clearance

Autor: PeggyRobinet, Jonathan DSmith

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 36

In a previous study, we identified autolysosome formation as the limiting step for turnover of cholesterol esters in lipid droplets of macrophage foam cells from the atherosclerosis sensitive DBA/2 strain compared to the atherosclerosis resistant AKR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21efda8726faf60ac97c905c26508876
https://doi.org/10.1161/atvb.36.suppl_1.550

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