Zobrazeno 1 - 10
of 32
pro vyhledávání: '"DAVID SCHAPIRO"'
Autor:
Shazia Ashraf, Hiroki Kudo, Jia Rao, Atsuo Kikuchi, Eugen Widmeier, Jennifer A. Lawson, Weizhen Tan, Tobias Hermle, Jillian K. Warejko, Shirlee Shril, Merlin Airik, Tilman Jobst-Schwan, Svjetlana Lovric, Daniela A. Braun, Heon Yung Gee, David Schapiro, Amar J. Majmundar, Carolin E. Sadowski, Werner L. Pabst, Ankana Daga, Amelie T. van der Ven, Johanna M. Schmidt, Boon Chuan Low, Anjali Bansal Gupta, Brajendra K. Tripathi, Jenny Wong, Kirk Campbell, Kay Metcalfe, Denny Schanze, Tetsuya Niihori, Hiroshi Kaito, Kandai Nozu, Hiroyasu Tsukaguchi, Ryojiro Tanaka, Kiyoshi Hamahira, Yasuko Kobayashi, Takumi Takizawa, Ryo Funayama, Keiko Nakayama, Yoko Aoki, Naonori Kumagai, Kazumoto Iijima, Henry Fehrenbach, Jameela A. Kari, Sherif El Desoky, Sawsan Jalalah, Radovan Bogdanovic, Nataša Stajić, Hildegard Zappel, Assel Rakhmetova, Sharon-Rose Wassmer, Therese Jungraithmayr, Juergen Strehlau, Aravind Selvin Kumar, Arvind Bagga, Neveen A. Soliman, Shrikant M. Mane, Lewis Kaufman, Douglas R. Lowy, Mohamad A. Jairajpuri, Richard P. Lifton, York Pei, Martin Zenker, Shigeo Kure, Friedhelm Hildebrandt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nephrotic syndrome is the second most common chronic kidney disease but there are no targeted treatment strategies available. Here the authors identify mutations of six genes codifying for proteins involved in cytoskeleton remodelling and modulation
Externí odkaz:
https://doaj.org/article/5fa7365ce28f4895a98f2773a190db3e
Autor:
Tilman Jobst-Schwan, Johanna Magdalena Schmidt, Ronen Schneider, Charlotte A Hoogstraten, Jeremy F P Ullmann, David Schapiro, Amar J Majmundar, Amy Kolb, Kaitlyn Eddy, Shirlee Shril, Daniela A Braun, Annapurna Poduri, Friedhelm Hildebrandt
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191503 (2018)
Until recently, morpholino oligonucleotides have been widely employed in zebrafish as an acute and efficient loss-of-function assay. However, off-target effects and reproducibility issues when compared to stable knockout lines have compromised their
Externí odkaz:
https://doaj.org/article/3a7df0901916417ab6e40b58846f00f8
Autor:
Emily R. Hankosky, David Schapiro, Karli B. Gunn, Elizabeth B. Lubelczyk, Jessica Mitroi, David R. Nelson
Publikováno v:
Diabetes Therapy. 14:967-975
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0b0efd1a27089b9e539f6595eee8bf
https://doi.org/10.1007/s13300-023-01399-0
https://doi.org/10.1007/s13300-023-01399-0
Autor:
David Schapiro, Rattan Juneja, Ahong Huang, Alexandra Meeks, Dongju Liu, Felicia T. Gelsey, Magaly Perez-Nieves
Publikováno v:
Diabetes Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62a1f8ca3f7740e9571de1bbd72f5a9a
https://doi.org/10.1007/s13300-023-01414-4
https://doi.org/10.1007/s13300-023-01414-4
Autor:
DAVID SCHAPIRO, ALEXANDRA MEEKS, DONGJU LIU, FELICIA GELSEY, RATTAN JUNEJA, MAGALY PEREZ-NIEVES, AHONG HUANG
Publikováno v:
Diabetes. 71
Background: In the past 5 years, type 2 diabetes practice guidelines have shifted to prioritize agents with cardiovascular (CV) and renal benefit. This study assessed whether real-world medication use has changed in line with these evolving guideline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::261d02eb19d8cda1131ac0c0915e46f0
https://doi.org/10.2337/db22-107-lb
https://doi.org/10.2337/db22-107-lb
Autor:
EMILY R. HANKOSKY, DAVID SCHAPIRO, KARLI B. GUNN, ELIZABETH LUBELCZYK, JESSICA MITROI, DAVID R. NELSON
Publikováno v:
Diabetes. 71
Background: HbA1c is a primary measure of glycemic control and managing HbA1c may help reduce the risk of complications. This study aimed to describe trends in HbA1c by insulin regimen. Methods: This was a retrospective analysis of cross-sectional su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aa43adafca1e3b5afd607cf4f943112
https://doi.org/10.2337/db22-658-p
https://doi.org/10.2337/db22-658-p
Autor:
SHRADDHA SHINDE, VIVIAN THIEU, ANITA KWAN, KATHERINE F. HOUGHTON, DAVID SCHAPIRO, JULIANA MEYERS
Publikováno v:
Diabetes. 71
Limited US real-world evidence exists on the effect of substantial changes in weight on HbA1c among people with T2D. People with T2D were identified from 2010-2018 in the IQVIA Ambulatory EMR database. The date of the first observed weight value was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9981771a2f09c75f032cd7f2cfe49eb7
https://doi.org/10.2337/db22-952-p
https://doi.org/10.2337/db22-952-p
Autor:
Makiko Nakayama, Johannes Wedel, Eugen Widmeier, Merlin Airik, Anish Nag, Catherine F. Clarke, Hannah Hugo, Rannar Airik, Jang Cho, Ronen Schneider, Markus Schueler, David Schapiro, Friedhelm Hildebrandt, Chandra C. Ghosh, Agape M. Awad
Publikováno v:
Journal of the American Society of Nephrology. 30:393-405
Background Although studies have identified >55 genes as causing steroid-resistant nephrotic syndrome (SRNS) and localized its pathogenesis to glomerular podocytes, the disease mechanisms of SRNS remain largely enigmatic. We recently reported that in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e187d4bc474e38b49c2ffe1fc453489
https://doi.org/10.1681/asn.2018060625
https://doi.org/10.1681/asn.2018060625
Autor:
Larissa Kerecuk, Tilman Jobst-Schwan, Weizhen Tan, Khalid A. Alhasan, Mais Hashem, Shrikant Mane, Jonathan Marquez, Seema Hashmi, Shahid Mahmood Baig, Svjetlana Lovric, Heon Yung Gee, Kaitlyn Eddy, Johanna Magdalena Schmidt, Sara Gonçalves, Jillian K. Warejko, Ayaz Khan, Mustafa K. Khokha, Charlotte A. Hoogstraten, Hannah Hugo, Mercedes Ubetagoyena, Birgit Budde, M. Asif, Amar J. Majmundar, Jennifer A. Lawson, Qian Shen, Gema Ariceta, Angelika A. Noegel, Tobias Hermle, Eugen Widmeier, Susanne Motameny, Nilufar Mohebbi, Friedhelm Hildebrandt, Janine Altmüller, Richard P. Lifton, Kathrin Schrage, Thomas M. Kitzler, Muhammad Sajid Hussain, Amy Kolb, Hanan M. Fathy, Arwa Ishaq A. Khayyat, Ankana Daga, Robert B. Ettenger, David Schapiro, Daniela A. Braun, Erkin Serdaroglu, Shirlee Shril, Hong Xu, Syeda Seema Waseem, Fowzan S. Alkuraya, Jia Rao, Ronen Schneider, C. Patrick Lusk, Daniel P. Gale, Corinne Antignac, Peter Nürnberg, Wolfram Antonin, Shazia Ashraf, Abubakar Moawia
Publikováno v:
Journal of Clinical Investigation, 128, 10, pp. 4313-4328
Journal of Clinical Investigation, 128, 4313-4328
Journal of Clinical Investigation, 128, 4313-4328
Item does not contain fulltext Steroid-resistant nephrotic syndrome (SRNS) almost invariably progresses to end-stage renal disease. Although more than 50 monogenic causes of SRNS have been described, a large proportion of SRNS remains unexplained. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6979adfd05bd79682da9891e50fcfe5b
https://doi.org/10.1172/jci98688
https://doi.org/10.1172/jci98688
Autor:
Friedhelm Hildebrandt, Weizhen Tan, Tobias Hermle, Merlin Airik, Shazia Ashraf, Johanna Magdalena Schmidt, Monkol Lek, Makiko Nakayama, Jitendra Kumar Meena, Jillian K. Warejko, Jing Chen, Arvind Bagga, Aditi Sinha, Amar J. Majmundar, Ankana Daga, Kristen M. Laricchia, Eugen Widmeier, Tilman Jobst-Schwan, Charlotte A. Hoogstraten, Hannah Hugo, Shirlee Shril, Jia Rao, David Schapiro, Daniela A. Braun, Ronen Schneider
Publikováno v:
American Journal of Medical Genetics Part A. 176:2460-2465
Galloway-Mowat syndrome (GAMOS) is a phenotypically heterogeneous disorder characterized by neurodevelopmental defects combined with renal-glomerular disease, manifesting with proteinuria. To identify additional monogenic disease causes, we here perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07860399956767ab4f6798473cd65245
https://doi.org/10.1002/ajmg.a.40489
https://doi.org/10.1002/ajmg.a.40489