Zobrazeno 1 - 10
of 697
pro vyhledávání: '"DAVID LANE"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 9, p e1010946 (2023)
Streptococcus pneumoniae (the pneumococcus) is well known for its ability to develop competence for natural DNA transformation. Competence development is regulated by an autocatalytic loop driven by variations in the basal level of transcription of t
Externí odkaz:
https://doaj.org/article/33a9d932c4c748fbad2095ab297ecc61
Autor:
David Lane, Teresa Schiller
Publikováno v:
Open Veterinary Journal, Vol 10, Iss 4, Pp 457-464 (2020)
Background: Bicipital tendinitis and/or tendinopathy is a common cause of forelimb lameness in dogs, particularly in larger and more active patients. Although conservative treatment aimed at resolving discomfort and preserving the tendon remains the
Externí odkaz:
https://doaj.org/article/c52deda96ad04d5e82d196f161371d15
Autor:
Sylvain Audibert, Nicolas Tanguy-le-Gac, Jérôme Rech, Catherine Turlan, Jean-Yves Bouet, Kerstin Bystricky, David Lane
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0226472 (2020)
The ParB-parS partition complexes that bacterial replicons use to ensure their faithful inheritance also find employment in visualization of DNA loci, as less intrusive alternatives to fluorescent repressor-operator systems. The ability of ParB molec
Externí odkaz:
https://doaj.org/article/6480096400254ff7860139c19c1a2c9e
Publikováno v:
Frontiers in Robotics and AI, Vol 6 (2019)
Learning from Demonstration (LfD) is a family of methods used to teach robots specific tasks. It is used to assist them with the increasing difficulty of performing manipulation tasks in a scalable manner. The state-of-the-art in collaborative robots
Externí odkaz:
https://doaj.org/article/29d25c7bbf3d48a088d6b0d90b8031f1
Publikováno v:
Clinical Practice and Cases in Emergency Medicine, Vol 3, Iss 4 (2019)
A 62-year-old woman with a history of metastatic breast cancer and known meningioma presented with unilateral vision loss associated with anisocoria and an afferent pupillary defect. On magnetic resonance imaging we found the cause to be optic nerve
Externí odkaz:
https://doaj.org/article/11d5f74015804a0c9e58f909b31314ab
Autor:
Cong Wang, Qifeng Zhang, Qiyan Tian, Shuo Li, Xiaohui Wang, David Lane, Yvan Petillot, Sen Wang
Publikováno v:
Sensors, Vol 20, Iss 3, p 939 (2020)
Mobile manipulation has a broad range of applications in robotics. However, it is usually more challenging than fixed-base manipulation due to the complex coordination of a mobile base and a manipulator. Although recent works have demonstrated that d
Externí odkaz:
https://doaj.org/article/32ba2c08e4364b51864f43d6682c073c
Autor:
Wen-Li Du, Nelly Dubarry, Fanny M Passot, Alain Kamgoué, Heath Murray, David Lane, Franck Pasta
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006172 (2016)
Bacterial genomes typically consist of a single chromosome and, optionally, one or more plasmids. But whole-genome sequencing reveals about ten per-cent of them to be multipartite, with additional replicons which by size and indispensability are cons
Externí odkaz:
https://doaj.org/article/8491729ae0404e8997cca601713552c9
Autor:
Hicham Saad, Franck Gallardo, Mathieu Dalvai, Nicolas Tanguy-le-Gac, David Lane, Kerstin Bystricky
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004187 (2014)
Chromosome breakage is a major threat to genome integrity. The most accurate way to repair DNA double strand breaks (DSB) is homologous recombination (HR) with an intact copy of the broken locus. Mobility of the broken DNA has been seen to increase d
Externí odkaz:
https://doaj.org/article/3bcfe8119b74426ca2f419e6c91a1213
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003956 (2013)
Hydrolysis of ATP by partition ATPases, although considered a key step in the segregation mechanism that assures stable inheritance of plasmids, is intrinsically very weak. The cognate centromere-binding protein (CBP), together with DNA, stimulates t
Externí odkaz:
https://doaj.org/article/105753344ab74800a7e84b4c396599d8
Autor:
Siau Jia Wei, Thomas Joseph, Sharon Chee, Ling Li, Larisa Yurlova, Kourosh Zolghadr, Christopher Brown, David Lane, Chandra Verma, Farid Ghadessy
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81068 (2013)
Pharmacological modulation of p53 activity is an attractive therapeutic strategy in cancers with wild-type p53. Presently in clinical trials, the small molecule Nutlin-3A competitively binds to HDM2, a key negative regulator of p53 and blocks its act
Externí odkaz:
https://doaj.org/article/25eb3a99f712477b8d46971a5e4fc205