Zobrazeno 1 - 10
of 1 067
pro vyhledávání: '"DAVID E. NEWBY"'
Autor:
Beth Whittington, Evangelos Tzolos, Shruti Joshi, Rong Bing, Jack Andrews, Krithika Loganath, Neil Craig, Craig Balmforth, Laura Clark, Christophe Lucatelli, Mark G MacAskill, Adriana A. S. Tavares, Tim Clark, Nicholas L. Mills, Jennifer Nash, Damini Dey, Piotr J. Slomka, Norman Koglin, Andrew W. Stephens, Marc R. Dweck, Michelle C. Williams, William Whiteley, Edwin J. R. van Beek, Joanna M. Wardlaw, David E. Newby
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract 18F-GP1 is a novel highly specific radiotracer that binds to activated platelets and thrombus. We aimed to establish the observer repeatability of coronary, carotid and cerebral 18F-GP1 uptake in patients presenting with acute myocardial inf
Externí odkaz:
https://doaj.org/article/194b1bf42855456291d6ae2505b2b1c3
Autor:
Fiona A. Chapman, Vanessa Melville, Emily Godden, Beth Morrison, Lorraine Bruce, Janet J. Maguire, Anthony P. Davenport, David E. Newby, Neeraj Dhaun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Chronic kidney disease (CKD) affects ~10% of the population and cardiovascular disease is its commonest complication. Despite treatment, patient outcomes remain poor and newer therapies are urgently needed. Here, we investigated the systemic
Externí odkaz:
https://doaj.org/article/a8c1638edaca4bb18b19ebe2771439f4
Autor:
Jolien Geers, Rong Bing, Tania A. Pawade, Mhairi K. Doris, Marwa Daghem, Alexander J. Fletcher, Audrey C. White, Laura Forsyth, Emily Evans, Jacek Kwieciński, Michelle C. Williams, Edwin J. R. van Beek, Soongu Kwak, Frederique E.C.M. Peeters, Evangelos Tzolos, Piotr J Slomka, Christophe Lucatelli, Stuart H. Ralston, Bernard Prendergast, David E. Newby, Marc R. Dweck
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 18 (2024)
Background Patients with osteoporosis demonstrate increased vascular calcification but the effect of osteoporosis treatments on vascular calcification remains unclear. The present study aimed to examine whether coronary or aortic calcification are in
Externí odkaz:
https://doaj.org/article/4f7a7d04a66b432a8697c04e1d27cc5f
Autor:
Alice M. Mezincescu, Amelia Rudd, Lesley Cheyne, Graham Horgan, Sam Philip, Donnie Cameron, Luc van Loon, Phil Whitfield, Rachael Gribbin, May Khei Hu, Mirela Delibegovic, Barbara Fielding, Gerald Lobley, Frank Thies, David E. Newby, Stuart Gray, Anke Henning, Dana Dawson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Despite opposing insulin sensitivity and cardiometabolic risk, both athletes and patients with type 2 diabetes have increased skeletal myocyte fat storage: the so-called “athlete’s paradox”. In a parallel non-randomised, non-blinded tr
Externí odkaz:
https://doaj.org/article/957aa207837340619ae8d6b6f4b7024b
Autor:
Robert J. H. Miller, Aditya Killekar, Aakash Shanbhag, Bryan Bednarski, Anna M. Michalowska, Terrence D. Ruddy, Andrew J. Einstein, David E. Newby, Mark Lemley, Konrad Pieszko, Serge D. Van Kriekinge, Paul B. Kavanagh, Joanna X. Liang, Cathleen Huang, Damini Dey, Daniel S. Berman, Piotr J. Slomka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Chest computed tomography is one of the most common diagnostic tests, with 15 million scans performed annually in the United States. Coronary calcium can be visualized on these scans, but other measures of cardiac risk such as atrial and ven
Externí odkaz:
https://doaj.org/article/4c588a8fbc88488b95dfaa67b3daf6af
Autor:
Victoria J. M. Reid, Wesley K. X. McLoughlin, Kalyani Pandya, Holly Stott, Monika Iškauskienė, Algirdas Šačkus, Judit A. Marti, Dominic Kurian, Thomas M. Wishart, Christophe Lucatelli, Dan Peters, Gillian A. Gray, Andrew H. Baker, David E. Newby, Patrick W. F. Hadoke, Adriana A. S. Tavares, Mark G. MacAskill
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Background Cardiac repair and remodeling following myocardial infarction (MI) is a multifactorial process involving pro-reparative inflammation, angiogenesis and fibrosis. Noninvasive imaging using a radiotracer targeting these processes cou
Externí odkaz:
https://doaj.org/article/b3fa38c72c4943ada2374cbe0f7b0709
Autor:
Kuan Ken Lee, David Lowe, Rachel O’Brien, Ryan Wereski, Anda Bularga, Caelan Taggart, Matthew T. H. Lowry, Amy V. Ferry, Michelle C. Williams, Giles Roditi, John Byrne, Chris Tuck, Denise Cranley, Praveen Thokala, Steve Goodacre, Catriona Keerie, John Norrie, David E. Newby, Alasdair J. Gray, Nicholas L. Mills
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background The majority of patients with suspected acute coronary syndrome presenting to the emergency department will be discharged once myocardial infarction has been ruled out, although a proportion will have unrecognised coronary artery
Externí odkaz:
https://doaj.org/article/22e4dfd581ee49c2a190a52b418f233f
Autor:
Abhishek Dattani, Saadia Aslam, Gaurav S. Gulsin, Aseel Alfuhied, Trisha Singh, Shruti S. Joshi, Lucy E. Kershaw, David E. Newby, Gerry P. McCann, Anvesha Singh
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 2, Pp 101074- (2024)
Background: Dysregulated myocardial calcium handling has been demonstrated in ischemic, non-ischemic and diabetic cardiomyopathy. Manganese-enhanced MRI (MEMRI) provides a unique method to quantify in-vivo myocardial calcium uptake but no studies hav
Externí odkaz:
https://doaj.org/article/11f43cb0aed2418aa9545b01f4e3dc4e
Autor:
Samuel Debono, Jennifer Nash, Alexander J. Fletcher, Maaz B. J. Syed, Scott I. Semple, Edwin J. R. van Beek, Alison Fletcher, Sebastien Cadet, Michelle C. Williams, Damini Dey, Piotr J. Slomka, Rachael O. Forsythe, Marc R. Dweck, David E. Newby
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Background Aortic microcalcification activity is a recently described method of measuring aortic sodium [18F]fluoride uptake in the thoracic aorta on positron emission tomography. In this study, we aimed to compare and to modify this method
Externí odkaz:
https://doaj.org/article/eef14a70d0534dd98dfdb62485573ed7
Autor:
Martin Lyngby Lassen, Evangelos Tzolos, Daniele Massera, Sebastien Cadet, Rong Bing, Jacek Kwiecinski, Damini Dey, Daniel S. Berman, Marc R. Dweck, David E. Newby, Piotr J. Slomka
Publikováno v:
EJNMMI Physics, Vol 9, Iss 1, Pp 1-15 (2022)
Abstract Background Current 18F-NaF assessments of aortic valve microcalcification using 18F-NaF PET/CT are based on evaluations of end-diastolic or cardiac motion-corrected (ECG-MC) images, which are affected by both patient and respiratory motion.
Externí odkaz:
https://doaj.org/article/e443a911196043f4853ff11cd6cda682