STRIVE pilot trial: a protocol for a multicentre pragmatic internal pilot randomised controlled trial of Structured TRaining to Improve fitness in a Virtual Environment (STRIVE) before surgery

Autor: Alan Forster, Nicola Edwards, Jean Wong, Frances Chung, Luke T Lavallée, François Lellouche, Monica Taljaard, Tim Ramsay, James Paul, Michael Schmidt, Manoj M Lalu, Jason Chui, Stephen Choi, Shelly Au, Richard Hall, Harsha Shanthanna, Hance Clarke, Stuart Mccluskey, Marcin Wasowicz, Karim Ladha, Angela Jerath, Daniel Sellers, Thomas Schricker, Roupen Hatzakorzian, Stephen Kowalski, James Green, Daniel I McIsaac, Guillaume Martel, Merrick Zwarenstein, Sylvain Boet, Kednapa Thavorn, I Singh, Karim Abdulla, Margaret L McNeely, Jessica Spence, Emilie Belley-Cote, Julie Hallet, Herman Sehmbi, Tarit Saha, David Rosen, George Wang, Connor Brenna, Tien Le, Ruth Graham, Husein Moloo, Hilary Grocott, Kelly Vogt, Gary Dobson, Faisal Siddiqui, Alexis Turgeon, Frédérick D’Aragon, Martin Girard, Brian Cuthbertson, Timothy Jackson, Ian Gilron, Norman Buckley, Andy Liu, Naveed Siddiqui, Leyla Baghirzada, Stephen Yang, William Wang, James Kim, Neil Goldenberg, Nicolas Beaudet, Dean Fergusson, Keyvan Karkouti, Jordan Tarshis, Colin McCartney, Vishal Uppal, Christopher Prabhakar, Derek Dillane, Jordan Leitch, Ramiro Arellano, Joel Parlow, George Djaiani, Lilia Kaustov, Peter Hedlin, Andrew Milne, Heather McDonald, David Boyle, Isabelle Raiche, Lara Williams, Emily Hladkowicz, Sylvain Gagne, Celena Scheede-Bergdahl, C David Mazer, Justyna Bartoszko, Chelsia Gillis, Michael Law, Edmond Li, Sarah Sinasac, Roberta DiDonato, Rene Martin, Thomas Hemmerling, Beverley Orser, Pierre Drolet, Vatsal Trivedi, Jason McVicar, Daniel Bainbridge, Pierre Beaulieu, Faraj Abdallah, Naheed Jivraj, Heather Pierce, Hema Bagry, Rakesh Sondekoppam, Christian Lehmann, John Fuller, Derek Roberts, Homer Yang, Stuart Wright, Michael Jacka, Curtis Nickel, Rodney Breau, Daenis Camire, Nidhi Charan, Louise Sun, Susan Lee, Rachel Khadaroo, Amanda Meliambro, Jennifer O’Brien, Renée El-Gabalawy, Daniel Trottier, Keely Barnes, Laura Boland, Karina Branje, Rosaleen Chun, Antoine Eskander, Joanne Hutton, John Joanisse, Cameron Love, Thomas Mutter, Sudhir Nagpal, Pablo Serrano, Carl van Walraven, Ilun Yang, Bryan Glezerson, Sylvie Aucoin, Rebecca Auer, Gregory Bryson, Dolores McKeen, Tyrone Harrison, Puneeta Tandon, Michael Verret, Sarah McMullen, William Beaubien-Souligny, Duminda Nalaka Wijeysundera, Samantha Russell, Victor Neira, Matthias Görges, Catherine Duclos, Etienne Couture, Diem Tran, Stephan Schwarz, Alana Flexman, Terri Sun, Michelle Mozel, Olivier Royer, Gurlavine Kidd, Tyler Chesney, Humberto R Vigil, Mary Farnand, Juliette Gaudreault, Bhagya Lakshmi Ramappa Tahasildar, Julian Mansour, William Scott Beattie, André Denault, Kathryn Sparrow, Jamal Alkadri, Saleh Al-Nahdi, Siniana Avramescu, Jonathan Bailey, Alex Bak, Gabriele Baldinii, Jean-Marie Bamvita, Jillian Banfield, Michael Bautista, Jean Beaubien, Gianluca Bertolizio, Guillaume Bousquet-Dion, Scott Brudney, Neville Burke, Jean Bussières, Matthew Cameron, Francois M Carrier, Françoise Chagnon, Anton Chau, Marshall Cheng, Gilles Chiniara, Janice Chisholm, Michelle Chiu, Chris Christodoulou, Pieter de Jager, Megan Deck, Ainsley Decker, Alain Deschamps, Daniel Dubois, Laura Duggan, Tristan Dumbarton, Deborah DuMerton Shore, Kaylene Duttchen, Darcie Earle, Marie-Pierre Gagne, Nicole Gibson, Andres-Felipe Gil, Talha Gondal, Daniel Gottesman, Alexander Gregory, Alexander Grunfeld, Gregory Hare, Jennifer Héroux, Orlando Hung, Janny Ke, Brent Kennedy, Brad Kerr, Margot Klemmer, Wing Lam, Danielle Lapierre, Jean-Sebastian Lebon, Vincent Lecluyse, Alexandre Lefebvre, Nagappa Mahes, William McKay, Perseus Missirlis, Glenio Mizubuti, Peter Moliner, Corentin Monfort, Janice Montbriand, Maliha Muneer, Allana Munro, Bhanu Nalla, Wayne Nates, David Neilpovitz, Angela Neufeld, Angélica Ostiguy, Charles Overbeek, Jean P Gelinas, Gilles Plourde, Jeremy Pridham, Mateen Raazi, Saifee Rashiq, Ravi Jayas, Ravi Taneja, Rebecca Grey, Tracey Rice, Richard N Merchant, David Roach, Roanne Preston, Ron Ree, Ronald George, Jean-Dennis Roy, Rudy Noppens, Ryan McGinn, Ryan Ramos, Sonia Sampson, Corey Sawchuk, Seyed Mahdi Sedighi, Surita Sidhu, Stephanie Sobotie, Sabri Soussi, Summer Sukh Brar, Varun Suresh, Vanessa Sweet, Linda Szabo, Edmond Tan, Mullein Thorleifson, Andrea Todd, Victor Tran, Dianshi Wang, Louie Wang, Geoff Warden, Kim Wong, Vincent Wourms, Cynthia Yarnold, Doreen Yee

Publikováno v: BMJ Open, Vol 14, Iss 11 (2024)

Introduction Home-based, virtually-supported care models may represent the most efficient and scalable approach to delivering prehabilitation services. However, virtual approaches to prehabilitation are understudied. This manuscript describes the pro

Externí odkaz: https://doaj.org/article/341d87b3ed5246df9fa767bcea6a1bc6

Influence of microplastic-associated biofilms on the bioavailability of a mixture of cadmium and benzo[a]pyrene by the analysis of biomarker gene expression in larval zebrafish

Autor: Marilena Di Natale, Ana Isabel Catarino, Stephen Summers, David Boyle, Marco Torri, Aldo Nicosia, Marianna Musco, Tiziana Masullo, Stefania Russo, Carmelo Daniele Bennici, Antonio Mazzola, Angela Cuttitta, Theodore B. Henry

Publikováno v: Ecological Indicators, Vol 152, Iss , Pp 110369- (2023)

Microplastics (MPs, 1 µm – 5 mm) in aquatic environments undergo complex weathering transformations such as those induced by microbial colonization and biofilm formation, that affect their ability to interact with environmental contaminants (co-co

Externí odkaz: https://doaj.org/article/22518fa89e224bb1bb9541d9ee3f0247

Demonstrating the translocation of nanoplastics across the fish intestine using palladium-doped polystyrene in a salmon gut-sac

Autor: Nathaniel J. Clark, Farhan R. Khan, Denise M. Mitrano, David Boyle, Richard C. Thompson

Publikováno v: Environment International, Vol 159, Iss , Pp 106994- (2022)

Fish are widely reported to ingest microplastics with low levels accumulating in the tissues, but owing to analytical constraints, much less is known about the potential accumulation of nanoplastics via the gut. Recently, the labelling of plastics wi

Externí odkaz: https://doaj.org/article/be599f6f67454580abaca426b94eee65

Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network

Autor: Richard A Furie, Andrew Filer, Michael H Weisman, Judith A James, Kenneth Kalunian, Chaim Putterman, H Michael Belmont, Ilfita Sahbudin, Karim Raza, Maria Dall'Era, Jill P Buyon, Diane L Kamen, Karen Salomon-Escoto, Kazuyoshi Ishigaki, Patrick Dunn, Betty Diamond, David Wofsy, Michele Bombardieri, Vivian Bykerk, Ming Wu, Soumya Raychaudhuri, Hemant Suryawanshi, Thomas Tuschl, Christopher Ritchlin, Maureen McMahon, Jennifer Grossman, Philip M Carlucci, Alessandra Nerviani, Peter M Izmirly, Fan Zhang, Felice Rivellese, Joan Bathon, Zhu Zhu, Qian Xiao, Jessica Li, Holden Maecker, Nir Hacohen, Jennifer Anolik, Javier Rangel-Moreno, Nida Meednu, Susan Goodman, Lindsy Forbess, Mariko Ishimori, Kevin Deane, David Hildeman, Yuhong Li, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Larry Moreland, Harris Perlman, Peter Gregersen, Celine C Berthier, Andrea Fava, David Boyle, Derek M Fine, Ami Ben-Artzi, P J Utz, Melanie Smith, Beatrice Goilav, Carla Cuda, Andrew McDavid, Joshua Keegan, Ilya Korsunsky, Joel Guthridge, Kevin Wei, Arnon Arazi, Thomas Eisenhaure, Michael Brenner, Susan Macwana, Pavel Morozov, Manjunath Kustagi, Gerald Watts, Kristina K Deonaraine, Jose Monroy-Trujillo, Mohamed G Atta, Kristin Haag, William Apruzzese, Sean Connery, Fernanda Payan-Schober, Kerry Cho, Jennifer Goff, Aparna Nathan, Joseph Mears, Nghia Millard, Kathryn Weinand, Saori Sakaue, Bill Robinson, Wade DeJager, Louis Bridges, Laura Donlin, Edward DiCarlo, Amit Lakhanpal, Heather Sherman, Anvita Singaraju, Lorien Shakib, Brendan Boyce, Darren Tabechian, Jen Albrecht, James Lederer, A Helena Jonsson, Daimon Simmons, Gregory Keras, Adam Chicoine, Zhihan Jian Li, Mandy McGeachy, Gary Firestein, Arnold Ceponis, Diane Horowitz, Salina Dominguez, Arthur Mandelin, Anjali Thakrar, Mike Holers, Jennifer Seifert, Constanino Pitzalis, Ellen Gravallese, Jennifer Barnas, Raymond Hsu, Steven Woodle, Paul Hoover, Michael Peters, Tony Jones, David Lieb, Jeffrey Hodgin, Raji Menon

Publikováno v: Lupus Science and Medicine, Vol 8, Iss 1 (2021)

Objectives In lupus nephritis the pathological diagnosis from tissue retrieved during kidney biopsy drives treatment and management. Despite recent approval of new drugs, complete remission rates remain well under aspirational levels, necessitating i

Externí odkaz: https://doaj.org/article/e3722c73b6ce45bba6e56c13af3b5745

'TORNADO' – Theranostic One-Step RNA Detector; microfluidic disc for the direct detection of microRNA-134 in plasma and cerebrospinal fluid

Autor: Hazel McArdle, Eva M. Jimenez-Mateos, Rana Raoof, Eadaoin Carthy, David Boyle, Hany ElNaggar, Norman Delanty, Hajo Hamer, Muejgdan Dogan, Tessa Huchtemann, Peter Kӧrtvelyessy, Felix Rosenow, Robert J. Forster, David C. Henshall, Elaine Spain

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Abstract Diagnosis of seizure disorders such as epilepsy currently relies on clinical examination and electroencephalogram recordings and is associated with substantial mis-diagnosis. The miRNA, miR-134 (MIR134 in humans), has been found to be elevat

Externí odkaz: https://doaj.org/article/82ad782d772448c6aa8e45ae4ebd31e4