Zobrazeno 1 - 10
of 30
pro vyhledávání: '"DANQI LIU"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundPolycystic ovary syndrome (PCOS) is a heterogeneous gynecological endocrine disorder linked to immunity. Cangfu Daotan Decoction (CFDT), a classic Chinese medicine prescription, is particularly effective in treating PCOS, specifically in pa
Externí odkaz:
https://doaj.org/article/ff78551c24794ed1a8d42326099437bd
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background In our previous investigation, we revealed a significant increase in the expression of microRNA-6881-3p (miR-6881-3p) in follicular fluid granulosa cells (GCs) from women with diminished ovarian reserve (DOR) compared to those wit
Externí odkaz:
https://doaj.org/article/2194e34593fc4de2a9225e41a012fcfb
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background At present, there are few studies on whether there is reproductive advantage in advanced polycystic ovary syndrome (PCOS) patients, and the existing research results are also controversial. Some research results show that the repr
Externí odkaz:
https://doaj.org/article/9405e1f2d3ed48429880866acd1245b5
Publikováno v:
BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Previous studies have shown that frozen embryo transfer (FET) resulted in increased live birth rates (LBR) and reduced the risk of ovarian hyperstimulation syndrome (OHSS) than did fresh embryo transfer in women with polycystic ov
Externí odkaz:
https://doaj.org/article/f422da1f1d0d47d595ecb2feb7e782f5
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Posaconazole (POS) has been reported to present potential antitumor activity for glioblastoma (GBM). However, its molecular mechanisms remain unclear. In this study, we found that POS has potent cytotoxicity and inhibits cell viability and proliferat
Externí odkaz:
https://doaj.org/article/fd1e0d4a7a9c47db9d73d66f6483b1d5
Publikováno v:
Mathematics, Vol 11, Iss 6, p 1479 (2023)
This paper focuses on the solutions for the distributed optimization coordination problem (DOCP) for heterogeneous multiagent systems under directed topologies. To begin with, a different convex optimization problem is proposed, which implies a weigh
Externí odkaz:
https://doaj.org/article/1827f55c7a7a4146a80626b0036cb20c
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 244 (2023)
In a preliminary study, we synthesized a series of new PDK1/MEK dual inhibitors. Antitumor activity screening showed that Compound YZT exerts a strong inhibitory action in A549 cells. However, the specific mechanism of YZT against non-small cell lung
Externí odkaz:
https://doaj.org/article/e63b6aae63044a18bb73a4fb48ea60f5
Autor:
Rangru Liu, Zutao Yu, Zhuo Chen, Danqi Liu, Fengying Huang, Qianbin Li, Gaoyun Hu, Xinan Yi, Xi Li, Honghao Zhou, Zhaoqian Liu
Publikováno v:
PeerJ, Vol 8, p e9981 (2020)
Background A novel dual MEK/PDK1 inhibitor named 9za has been synthesized by our research team. Preliminary study showed that 9za possessed potent cytotoxicity and proapoptosis in non-small cell lung cancer (NSCLC) cells. Nevertheless, the precise un
Externí odkaz:
https://doaj.org/article/c541aaa1e8034672878d46f2fed420a0
Publikováno v:
PeerJ, Vol 8, p e9422 (2020)
Bladder cancer (BC) is the ninth most common malignancy worldwide. Bladder urothelial carcinoma (BLCA) constitutes more than 90% of bladder cancer (BC). The five-year survival rate is 5–70%, and patients with BLCA have a poor clinical outcome. The
Externí odkaz:
https://doaj.org/article/2092a90b39e54987b0ec9ec834336bf1
Publikováno v:
PeerJ, Vol 8, p e8504 (2020)
Background Gastric carcinoma is a very diverse disease. The progression of gastric carcinoma is influenced by complicated gene networks. This study aims to investigate the actual and potential prognostic biomarkers related to survival in gastric carc
Externí odkaz:
https://doaj.org/article/28cf5107d54243be91a95bdc11c746a5