Zobrazeno 1 - 9
of 9
pro vyhledávání: '"DANIEL APPLEDORN"'
Autor:
Gillian Lovell, Daniel A. Porto, Jasmine Trigg, Nevine Holtz, Nicola Bevan, Timothy Dale, Daniel Appledorn
Publikováno v:
Cancer Research. 83:5418-5418
The increasing use of precious, patient-derived cells has driven the need for non-perturbing and label-free cell measurements, particularly in the oncology field. To address this we developed the Incucyte® AI Cell Health Analysis Software Module, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c7b5c88daef6cc1140755ca328938a9
https://doi.org/10.1158/1538-7445.am2023-5418
https://doi.org/10.1158/1538-7445.am2023-5418
Publikováno v:
Cancer Research. 82:3084-3084
Organoid technologies are increasingly being used as in-vitro models of human development and disease as they exhibit structural, morphogenetic, and functional properties that recapitulate in vivo pathophysiology. To successfully use these models acr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55ca0c5d278cd5573791aac98149e77b
https://doi.org/10.1158/1538-7445.am2022-3084
https://doi.org/10.1158/1538-7445.am2022-3084
Autor:
DANIEL APPLEDORN, Gillian Lovell, Clare Szybut, Kalpana Patel, Hinnah Campwala, Nicola Bevan, Tim Dale, Derek Trezise
Publikováno v:
The Journal of Immunology. 198:81.15-81.15
CD47 is a trans-membrane “don’t-eat-me” signaling protein that enables tumor cells to evade clearance by neighboring phagocytes. Blocking CD47 allows phagocytes to clear tumor cells and is a promising new approach for cancer immunotherapy. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac2ec1b30cc781c22aeee14c81d9243e
https://doi.org/10.4049/jimmunol.198.supp.81.15
https://doi.org/10.4049/jimmunol.198.supp.81.15
Publikováno v:
The Journal of Immunology. 196:60.25-60.25
Macrophages are crucial regulators of homeostasis, however, their functions can be compromised, leading to a wide variety of diseases such as diabetes, fibrosis, atherosclerosis and tumor metastasis. Macrophage recruitment by cytokines is an essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc52fed16e65b638f98d577eb479328
https://doi.org/10.4049/jimmunol.196.supp.60.25
https://doi.org/10.4049/jimmunol.196.supp.60.25
Publikováno v:
The Journal of Immunology. 196:119.22-119.22
The recruitment of leukocytes to sites of infection and their migration through the endothelium are critical to immune responses. Transendothelial migration is essential for leukocytes to respond to foreign microorganisms, but if uncontrolled, can ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45e1a0de98cd6be8f12f101ea8a498f0
https://doi.org/10.4049/jimmunol.196.supp.119.22
https://doi.org/10.4049/jimmunol.196.supp.119.22
Publikováno v:
The Journal of Immunology. 194:185.17-185.17
Chemotactic-driven cell migration is an important biological process in many areas of life science research including immunology, cancer and developmental biology. The dominant high-throughput (96-well format) solution for measuring cellular chemotax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c5dd4e9cfd6094b03b6137b6bb0dea3
https://doi.org/10.4049/jimmunol.194.supp.185.17
https://doi.org/10.4049/jimmunol.194.supp.185.17
Autor:
Shipra Shahi, Sonika Patial, Yogesh Saini, Daniel Appledorn, John Lapres, Andrea Amalfitano, Narayanan Parameswaran
Publikováno v:
The Journal of Immunology. 184:94.11-94.11
Toll-like receptor-4 (TLR4) activated by lipopolysaccharide (LPS) is involved in a number of inflammatory diseases, in part via activation of NFκB pathway. G-protein coupled receptor kinase-5 (GRK5), a serine-threonine kinase originally discovered f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceccc268ceed882d555b2305fdcd1bcd
https://doi.org/10.4049/jimmunol.184.supp.94.11
https://doi.org/10.4049/jimmunol.184.supp.94.11
β-arrestins mediate lipopolysaccharide-induced inflammatory response and endotoxemia in mice (94.10)
Autor:
Narayanan Parameswaran, Babu Gonipeta, Sitaram Parvataneni, Daniel Appledorn, Sonika Patial, Venugopal Gangur, Andrea Amalfitano, Katie Porter
Publikováno v:
The Journal of Immunology. 184:94.10-94.10
β-arrestins are scaffolding proteins recently implicated as negative regulators of Toll-like receptor-4 (receptor for lipopolysaccharide from gram-negative bacteria) signaling in macrophages and fibroblasts. Unexpectedly, we find that β-arrestin-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d708db9ac9b386bbe0f2bc43a69102a8
https://doi.org/10.4049/jimmunol.184.supp.94.10
https://doi.org/10.4049/jimmunol.184.supp.94.10
Autor:
Zachary Hartman, Daniel Appledorn, Todd Mendelson, Herbert Kim Lyerly, Tim Clay, Andrea Amalfitano
Publikováno v:
The Journal of Immunology. 178:S71-S71
Human Adenovirus Type 4 is widely known as the responsible agent for epidemic outbreaks of Acute Respiratory Disease in military recruits. Although studied for over 50 years, we still have precious little insight into the epidemiology and high viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74f122d48e05fd9ed58af12f0f0c36d
https://doi.org/10.4049/jimmunol.178.supp.47.24
https://doi.org/10.4049/jimmunol.178.supp.47.24