Zobrazeno 1 - 10
of 737
pro vyhledávání: '"DAN, Rujescu"'
Autor:
Jakob Unterholzner, Alexander Kautzky, Murray Bruce Reed, Theresa Friederike Wechsler, Valentin Popper, Benjamin Spurny-Dworak, Peter Stöhrmann, Manfred Klöbl, Nimmy Varghese, Andreas Mühlberger, Anne Eckert, Richard Frey, Dan Rujescu, Rupert Lanzenberger, Thomas Vanicek
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Defying the COVID-19 pandemic required restriction measures of unprecedented scale, that may induce and exacerbate psychiatric symptoms across the population. We aimed to assess in vivo dynamic effects of mitigation strategies on human brain
Externí odkaz:
https://doaj.org/article/4f2334824c8b41a9b815374f74188702
Autor:
Anna Schulze, Fabian Streit, Lea Zillich, Swapnil Awasthi, Alisha S. M. Hall, Martin Jungkunz, Nikolaus Kleindienst, Josef Frank, Cornelia E. Schwarze, Norbert Dahmen, Björn H. Schott, Markus Nöthen, Arian Mobascher, Dan Rujescu, Klaus Lieb, Stefan Roepke, Sabine C. Herpertz, Christian Schmahl, Martin Bohus, Stephan Ripke, Marcella Rietschel, Stefanie Lis, Stephanie Witt
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Loneliness, influenced by genetic and environmental factors such as childhood maltreatment, is one aspect of interpersonal dysfunction in Borderline Personality Disorder (BPD). Numerous studies link loneliness and BPD and twin studies indica
Externí odkaz:
https://doaj.org/article/ef08137eb7224fa092485e864d31d017
Autor:
David Pellerin, Felix Heindl, Carlo Wilke, Matt C. Danzi, Andreas Traschütz, Catherine Ashton, Marie-Josée Dicaire, Alexanne Cuillerier, Giulia Del Gobbo, Kym M. Boycott, Jens Claassen, Dan Rujescu, Annette M. Hartmann, Stephan Zuchner, Bernard Brais, Michael Strupp, Matthis Synofzik
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105076- (2024)
Summary: Background: GAA-FGF14 disease/spinocerebellar ataxia 27B is a recently described neurodegenerative disease caused by (GAA)≥250 expansions in the fibroblast growth factor 14 (FGF14) gene, but its phenotypic spectrum, pathogenic threshold, a
Externí odkaz:
https://doaj.org/article/6a45cfb1de324e61a33fa2a7a9970a69
Autor:
Undine Haferkamp, Carla Hartmann, Chaudhry Luqman Abid, Andreas Brachner, Alevtina Höchner, Anna Gerhartl, Bernadette Harwardt, Selin Leckzik, Jennifer Leu, Marco Metzger, Marina Nastainczyk-Wulf, Winfried Neuhaus, Sabrina Oerter, Ole Pless, Dan Rujescu, Matthias Jung, Antje Appelt-Menzel
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract Background The function of the blood-brain barrier (BBB) is impaired in late-onset Alzheimer disease (LOAD), but the associated molecular mechanisms, particularly with respect to the high-risk APOE4/4 genotype, are not well understood. For t
Externí odkaz:
https://doaj.org/article/e79d3dddebfc4e0ba9d9d75350e53843
Autor:
Viktor B. Nöhles, Felix Bermpohl, Peter Falkai, Christine Reif-Leonhard, Frank Jessen, Mazda Adli, Christian Otte, Andreas Meyer-Lindenberg, Michael Bauer, Kerstin Rubarth, Ion-George Anghelescu, Dan Rujescu, Christoph U. Correll
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Suicidality, ranging from passive suicidal thoughts to suicide attempt, is common in major depressive disorder (MDD). However, relatively little is known about patient, illness and treatment characteristics in those with co-occurr
Externí odkaz:
https://doaj.org/article/4f59fd1d287e4c0da94e3e0da9dbe5b7
Autor:
Hannah Stocker, Kira Trares, Léon Beyer, Laura Perna, Dan Rujescu, Bernd Holleczek, Konrad Beyreuther, Klaus Gerwert, Ben Schöttker, Hermann Brenner
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-9 (2023)
Abstract Background In order to utilize polygenic risk scores (PRSs) for Alzheimer’s disease (AD) in a meaningful way, influential factors (i.e. training set) and prediction across groups such as APOE e4 (APOE4) genotype as well as associations to
Externí odkaz:
https://doaj.org/article/6bebce118115470eb721c902d18273b7
Autor:
Marie Spies, Matej Murgaš, Chrysoula Vraka, Cecile Philippe, Gregor Gryglewski, Lukas Nics, Theresa Balber, Pia Baldinger-Melich, Annette M. Hartmann, Dan Rujescu, Marcus Hacker, Edda Winkler-Pjrek, Dietmar Winkler, Rupert Lanzenberger
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Variants within the monoamine oxidase A (MAO-A, MAOA) and tryptophan hydroxylase 2 (TPH2) genes, the main enzymes in cerebral serotonin (5-HT) turnover, affect risk for depression. Depressed cohorts show increased cerebral MAO-A in positron
Externí odkaz:
https://doaj.org/article/9ecc75b305cf4506a06a2fedef345416
Autor:
Gabriela Xavier, Alexander Navarrete Santos, Carla Hartmann, Marcos L. Santoro, Nicole Flegel, Jessica Reinsch, Annika Majer, Toni Ehrhardt, Jenny Pfeifer, Andreas Simm, Thomas Hollemann, Sintia I. Belangero, Dan Rujescu, Matthias Jung
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3575 (2024)
The pathophysiology of many neuropsychiatric disorders is still poorly understood. Identification of biomarkers for these diseases could benefit patients due to better classification and stratification. Exosomes excreted into the circulatory system c
Externí odkaz:
https://doaj.org/article/c36f6bf669684962a19fe94934e282f0
Autor:
Victoria Watzal, Godber Mathis Godbersen, Ana Weidenauer, Matthäus Willeit, Valentin Popper, Michael Treiber, Maximilian Preiss, Dominik Ivkic, Ulrich Rabl, Gernot Fugger, Richard Frey, Christoph Kraus, Dan Rujescu, Lucie Bartova
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
The second-generation anticonvulsant lamotrigine is widely used in the psychiatric field as a mood stabilizer or antidepressant augmentation therapy. Although particularly older anticonvulsants are known for their potential to cause hypersensitivity
Externí odkaz:
https://doaj.org/article/5afa31fea5e2458cae3bf1cb75f8004b
Autor:
Maximilian Preiss, Ulrich Rabl, Valentin Popper, Victoria Watzal, Michael Treiber, Dominik Ivkic, Nicole Praschak-Rieder, Angela Naderi-Heiden, Gernot Fugger, Richard Frey, Dan Rujescu, Lucie Bartova
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
The non-benzodiazepine hypnotic zolpidem is frequently administered as a short term psychopharmacotherapy for insomnia. Although it is well-established in a broad clinical routine and often well-tolerated, severe delirium and complex sleep behavior w
Externí odkaz:
https://doaj.org/article/7c680d82198b450e93a098d5c94af2a3