Zobrazeno 1 - 10
of 2 418
pro vyhledávání: '"DAMGO"'
Autor:
Kianoush Missaghi, Jean-Patrick Le Gal, Julien Mercier, Martin Grover, Philippe-Antoine Beauséjour, Shannon Chartré, Omima Messihad, François Auclair, Réjean Dubuc
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2024)
In lampreys, respiration consists of a fast and a slow rhythm. This study was aimed at characterizing both anatomically and physiologically the brainstem regions involved in generating the two rhythms. The fast rhythm generator has been located by us
Externí odkaz:
https://doaj.org/article/1f65a85d3ee847d29e67bb7187dabdb6
Akademický článek
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Akademický článek
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Autor:
Sergey Sudakov, Natalia Bogdanova
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2021)
The involvement of peripheral opioid receptors in the mechanisms of eating behavior is still unclear. The aim of this work was to study the role of peripheral, predominantly gastric mu and delta opioid receptors in the realization of food motivation
Externí odkaz:
https://doaj.org/article/f577984d340b42aab66e481f74ac4794
Autor:
Agata Binienda, Adam Makaro, Marcin Talar, Julia B. Krajewska, Aleksandra Tarasiuk, Adrian Bartoszek, Adam Fabisiak, Paula Mosińska, Karolina Niewinna, Katarzyna Dziedziczak, Mikołaj Świerczyński, Radzisław Kordek, Maciej Salaga, Jakub Fichna
Publikováno v:
Molecules, Vol 26, Iss 22, p 6827 (2021)
Background: Recent studies suggest that lipids, including free fatty acids (FFAs), are necessary for proper μ opioid receptor (MOR) binding and that activation of opioid receptors (ORs) improves intestinal inflammation. The objective of the study wa
Externí odkaz:
https://doaj.org/article/dec6719a244a4da589acc3de5e7f7370
Publikováno v:
Molecules, Vol 26, Iss 15, p 4509 (2021)
Opioid-associated overdoses and deaths due to respiratory depression are a major public health problem in the US and other Western countries. In the past decade, much research effort has been directed towards the development of G-protein-biased µ-op
Externí odkaz:
https://doaj.org/article/873f5bca910c49588df52d473dc5f055
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Neuropathic pain often arises from damage to peripheral nerves and is difficult to treat. Activation of opioid receptors in peripheral sensory neurons is devoid of respiratory depression, sedation, nausea, and addiction mediated in the brain, and ame
Externí odkaz:
https://doaj.org/article/8cc583f2195947f6b4fd1151f247c2f2
Autor:
Yun K. Hahn, Jason J. Paris, Aron H. Lichtman, Kurt F. Hauser, Laura J. Sim-Selley, Dana E. Selley, Pamela E. Knapp
Publikováno v:
Neurobiology of Disease, Vol 92, Iss , Pp 124-136 (2016)
Co-exposure to opiates and HIV/HIV proteins results in enhanced CNS morphological and behavioral deficits in HIV+ individuals and in animal models. Opiates with abuse liability, such as heroin and morphine, bind preferentially to and have pharmacolog
Externí odkaz:
https://doaj.org/article/46a94e8e2b4741659b64212514726b3d
Publikováno v:
Molecules, Vol 25, Iss 9, p 2087 (2020)
The mu opioid receptor (MOR) is the primary target for analgesia of endogenous opioid peptides, alkaloids, synthetic small molecules with diverse scaffolds, and peptidomimetics. Peptide-based opioids are viewed as potential analgesics with reduced si
Externí odkaz:
https://doaj.org/article/85cd8759a62b46fa8adb6ffb1d6cb1a5
Publikováno v:
Neuroreport
Objective The combination of opioids and ethanol can synergistically depress breathing and the acute ventilatory response to hypoxia. Multiple studies have shown that the underlying mechanisms for this may involve calcium channel inhibition in centra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74421464ad3a955e6d915275c75fb6ae
https://doi.org/10.1097/wnr.0000000000001726
https://doi.org/10.1097/wnr.0000000000001726