Zobrazeno 1 - 10
of 19
pro vyhledávání: '"DALE D. MANESS"'
Publikováno v:
Drug Development Communications. 1:369-387
The solvent and melt methods were employed to prepare solid dispersions with various water soluble carriers and a slightly soluble drug, sulfabenzamide. The carriers investigated included citric acid, succinic acid, dextrose, polyethylene glycol 6000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25b4abdf9d8f421448eb3f9d179bbf4b
https://doi.org/10.3109/03639047409088185
https://doi.org/10.3109/03639047409088185
Publikováno v:
International Journal of Pharmaceutics. 2:275-281
Furosemide, a potent diuretic, has been found to give a low bioavailability profile when administered orally which potentially could be due to hydrolysis of the drug prior to absorption. An in vitro kinetic study was performed to elucidate the kineti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2f3971cc990d34073517bce44214820
https://doi.org/10.1016/0378-5173(79)90034-6
https://doi.org/10.1016/0378-5173(79)90034-6
Publikováno v:
Journal of Pharmaceutical Sciences. 66:795-798
The hydrolysis of nitrazepam involves a two-step sequential mechanism. The intermediate is the ring-opened compound resulting from scission of the azomethine bond. The final products are glycine and 2-amino-5-ni-robenzophenone. Recyclization of the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5e5eb61289ad177997c35f5bae9760
https://doi.org/10.1002/jps.2600660613
https://doi.org/10.1002/jps.2600660613
Publikováno v:
Microchemical Journal. 22:168-175
Erythromycin forms association complexes with four sulfonic acid dyes that can be extracted into chloroform and quantified by spectrophotometry. Of the dyes studied, MO and O IV form 1:1 complexes with the conjugate acid of erythromycin. Solutions co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5b22658c602950537772b9fcfe2fceb
https://doi.org/10.1016/0026-265x(77)90084-4
https://doi.org/10.1016/0026-265x(77)90084-4
Publikováno v:
Journal of Pharmaceutical Sciences. 65:1198-1204
Differential absorbance spectroscopy was successfully used to follow the hydrolysis kinetics of chlordiazepoxide and demoxepam from pH 1 to 11. Loss of the methylamino group from chlordiazepoxide produced demoxepam. Demoxepam degraded by a parallel c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fec49f2fff74650767cae7c3949a1f4
https://doi.org/10.1002/jps.2600650817
https://doi.org/10.1002/jps.2600650817
Publikováno v:
Microchemical Journal. 23:51-55
A sensitive procedure has been developed for analysis of solutions of the macrolide antibiotic, erythromycin. The method is based on ion-pair formation of the conjugate acid of the drug with an 35 S-labeled isostere of methyl orange, partitioning int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17a9d16ddca6136a2784f68e2c9c073
https://doi.org/10.1016/0026-265x(78)90038-3
https://doi.org/10.1016/0026-265x(78)90038-3
Publikováno v:
Journal of the American College of Toxicology. 4:53-61
Sterigmatocystin, a mycotoxin produced by several fungi, is carcinogenic when injected subcutaneously in rats. The potential of sterigmatocystin as a contaminant to human foodstuffs makes understanding its absorption, distribution, metabolism, and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc185ba1116a9d09664abf1ca65d505
https://doi.org/10.3109/10915818509014504
https://doi.org/10.3109/10915818509014504
Publikováno v:
Analytical Letters. 10:719-731
A sensitive and selective method for the determination of erythromycin in human blood serum, in the range of 0.1 to 1.0 μg/ml, is described. The procedure is based on extraction of drug into ether and competitive displacement of [14C]-erythromycin f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de0a21fcea7c5c5a6f3dc293f2a0298
https://doi.org/10.1080/00032717708059237
https://doi.org/10.1080/00032717708059237
Publikováno v:
Journal of the American College of Toxicology. 4:45-51
Sterigmatocystin, a secondary fungal metabolite, produces a toxic reaction upon administration to experimental animals. Examination of rats that have received multiple doses of 14C-sterigmatocystin may indicate the response elicited by repeated expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0616de86eaa5757c916f2e4c1bcf2ac0
https://doi.org/10.3109/10915818509014503
https://doi.org/10.3109/10915818509014503
Publikováno v:
Journal of Chromatography A. 116:490-492
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d61bbcd891b34e17ed8895872b4589e
https://doi.org/10.1016/s0021-9673(00)89926-4
https://doi.org/10.1016/s0021-9673(00)89926-4