Zobrazeno 1 - 10
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pro vyhledávání: '"DAI, Disease Activity Index"'
Akademický článek
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Autor:
Yusuke Yasutomi, Ryuichi Okamoto, Keiichi Haga, Ayako Makiyama, Goh Murayama, Asako Chiba, Sachiko Miyake, Mamoru Watanabe, Taiga Kuga, Takashi Nagaishi, Akihito Nagahara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 81-93 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 81-93 (2022)
Background & Aims Mucosal-associated invariant T (MAIT) cells are innate-like T cells restricted by major histocompatibility complex-related molecule 1 (MR1) and express a semi-invariant T cell receptor. Previously, we reported the activation status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a988b2e1e30a9756a161039143fdfb
https://doi.org/10.1016/j.jcmgh.2021.08.018
https://doi.org/10.1016/j.jcmgh.2021.08.018
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2880-2899 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2880-2899 (2021)
Aberrant activation of NLRP3 inflammasome in colonic macrophages strongly associates with the occurrence and progression of ulcerative colitis. Although targeting NLRP3 inflammasome has been considered to be a potential therapy, the underlying mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b197d7e1bd61447a9d7a45da0a56387
https://doi.org/10.1016/j.apsb.2021.03.011
https://doi.org/10.1016/j.apsb.2021.03.011
Autor:
Vijay R. Chidrawar, Bader Alsuwayt
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
In the present study, we have investigated and/or compared the role of glibenclamide, G as cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor, and lubiprostone, L as chloride channel-2 (ClC-2) activator in the 2,4-dinitrobenzene sul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae14bfe965e654468af30a05663d9b28
https://doi.org/10.1016/j.jsps.2021.02.005
https://doi.org/10.1016/j.jsps.2021.02.005
Autor:
Chuyao Liao, Di Wang, Ying Zhang, Zunjian Zhang, Fengguo Xu, Siyuan Qin, Yuxin Zhang, Danting Li, Yuan Tian, Jie Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 763-780 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Intestinal toxicity induced by chemotherapeutics has become an important reason for the interruption of therapy and withdrawal of approved agents. In this study, we demonstrated that chemotherapeutics-induced intestinal damage were commonly character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af930bc5ea3c9fbae9d582539b35a5f
https://doi.org/10.1016/j.apsb.2020.07.017
https://doi.org/10.1016/j.apsb.2020.07.017
Autor:
Iulia Oancea, Andy Wu, Michael A. McGuckin, Sumaira Z. Hasnain, Rabina Giri, John D. Hooper, Veronika Schreiber, Brett C McWhinney, Julie M. Davies, Jakob Begun, Yonghua Sheng, David P. Fairlie, Saleh Y. Alabbas, Gregor Kijanka, Yaowu He, Ramya Movva, Andrew J. Lucke, Timothy H. Florin
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 33-53 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Chronic bowel inflammation increases the risk of colon cancer; colitis-associated cancer (CAC). Thiopurine treatments are associated with a reduction in dysplasia and CAC in inflammatory bowel disease (IBD). Abnormal Wnt/β-catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f601ccce23a182b6171ce5a7c5598ec
http://www.sciencedirect.com/science/article/pii/S2352345X20300886
http://www.sciencedirect.com/science/article/pii/S2352345X20300886
Autor:
Aralia Leon-Coria, Manish Kumar, Matthew Workentine, France Moreau, Michael Surette, Kris Chadee
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 77-98 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 77-98 (2021)
Background & Aims Alterations in intestinal MUC2 mucin and microbial diversity are closely linked with important intestinal pathologies; however, their impact on each other and on intestinal pathogenesis has been vaguely characterized. Therefore, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ef6f03e7145e2cd814002bfa26033a
https://doi.org/10.1016/j.jcmgh.2020.07.003
https://doi.org/10.1016/j.jcmgh.2020.07.003
Autor:
Anita Krnjic, Vineeta Khare, Maximilian Baumgartner, Ildiko Mesteri, Christoph Gasche, Kyle Dammann, Adrian Frick, Kristine Jimenez, Christina Gmainer, Michaela Lang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 892-907.e1 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims p21-activated kinase-1 (PAK1) belongs to a family of serine-threonine kinases and contributes to cellular pathways such as nuclear factor-κB (NF-κB), mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase/protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f65df8854ce99ea42cd0b4240cfb89f
http://www.sciencedirect.com/science/article/pii/S2352345X20301806
http://www.sciencedirect.com/science/article/pii/S2352345X20301806
Autor:
Hamid M. Said, Jonathan Skupsky, Michael D. Cahalan, Manando Nakasaki, Subrata Sabui, Michael Hwang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 557-567 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 9, iss 4
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 9, iss 4
Background & Aims Biotin is a water-soluble vitamin that is indispensable for human health. Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and conjunctivitis. We previously reported that biotin deficiency also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029c0f847cebcdc15768f41ddd88e494
http://www.sciencedirect.com/science/article/pii/S2352345X19301663
http://www.sciencedirect.com/science/article/pii/S2352345X19301663
Autor:
Ryo Aoki, Toshiaki Teratani, Mari Mochizuki Arai, Kentaro Miyamoto, Yohei Mikami, Shinta Mizuno, Yosuke Harada, Ena Nomura, Takanori Kanai, Tomohisa Sujino, Hiroki Kiyohara, Makoto Naganuma, Yuzo Koda, Tadakazu Hisamatsu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 135-156 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 135-156 (2019)
Background & Aims Psoriasis and inflammatory bowel disease (IBD) are both chronic inflammatory diseases occurring in the skin and gut, respectively. It is well established that psoriasis and IBD have high concordance rates, and similar changes in imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668b6a6b782f67938742bda84ab27a4c
https://doi.org/10.1016/j.jcmgh.2018.09.010
https://doi.org/10.1016/j.jcmgh.2018.09.010