Zobrazeno 1 - 10
of 22
pro vyhledávání: '"D.S. Dalafave"'
Autor:
Krupa S. Jani, D.S. Dalafave
Publikováno v:
Bioinformatics and Biology Insights, Vol 2012, Iss 6, Pp 23-31 (2012)
Externí odkaz:
https://doaj.org/article/848e0566e7bf4aee91d37fa8f1ef2774
Autor:
D.S. Dalafave
Publikováno v:
Biomedical Engineering and Computational Biology, Vol 2010, Iss 2, Pp 11-21 (2010)
Externí odkaz:
https://doaj.org/article/39d54aa4acf04e9e9f6bc0b94965c9a4
Autor:
D.S. Dalafave, G. Prisco
Publikováno v:
Cancer Informatics, Vol 2010, Iss 9, Pp 169-177 (2010)
Informatics and computational design methods were used to create new molecules that could potentially bind antiapoptotic proteins, thus promoting death of cancer cells. Apoptosis is a cellular process that leads to the death of damaged cells. Its mal
Externí odkaz:
https://doaj.org/article/d7da9e449dd64f3ea124a6e0968030e6
Autor:
D.S. Dalafave
Publikováno v:
Design Principles and Practices: An International Journal—Annual Review. 4:173-182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c234da0054d7b55a34ccc373ef57f20
https://doi.org/10.18848/1833-1874/cgp/v04i02/37854
https://doi.org/10.18848/1833-1874/cgp/v04i02/37854
Autor:
D.S. Dalafave
Publikováno v:
Materials Chemistry and Physics. 119:195-200
Thermoelectric properties of Re6GaxSeyTe15−y (0 ≤ x ≤ 2; 0 ≤ y ≤ 7.5) were studied in the temperature range 90–320 K. The measurements revealed p-type semi-conductivity in all samples. Relatively high values of the Seebeck coefficients,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b10fe4822421402e884423c2623a259
https://doi.org/10.1016/j.matchemphys.2009.08.061
https://doi.org/10.1016/j.matchemphys.2009.08.061
Autor:
R.E. Dalafave, D.S. Dalafave
Publikováno v:
Biophysical Journal. 108(2)
This research addresses computational design of small drug-like molecules that could potentially inhibit AKT and SGK kinases and thus stave off cancer advancement. AKT and SGK belong to the AGC group of protein kinases. They regulate important cell f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1760ace13e9cd3c11c1a1497f553f1ce
Autor:
D.S. Dalafave
Publikováno v:
Biophysical Journal. 104(2)
The research addresses computational design of small druglike molecules for possible anticancer applications. Polo-like kinase 1 (Plk1) is a main regulator of mitosis. Its inhibition can lead to apoptosis of cancer cells. Most kinases interact with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2329e859ac7933f55f0ea7ae0808d995
Autor:
D.S. Dalafave
Publikováno v:
Biophysical Journal. 106(2):409a-410a
Glioblastoma multiforme (GBM), a very aggressive brain tumor, has a median survival of only 14 months. LYN, an important kinase involved in regulation of hematopoietic cells, is significantly overexpressed in GBM. It is believed that LYN promotes mig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb845f8df905218bc292f073aad7900
Autor:
D.S. Dalafave
Publikováno v:
Biophysical Journal. 102:61a
Glioblastoma multiforme (GBM) is a very aggressive brain cancer in humans. Even with improvements in surgical, radiation, and chemotherapy treatments, current prognosis is bleak, with only a 14-month median survival time. LYN, an important kinase inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09d20fa9f1d4bd13babca91831b8665
https://doi.org/10.1016/j.bpj.2011.11.362
https://doi.org/10.1016/j.bpj.2011.11.362
Autor:
K.S. Jani, D.S. Dalafave
Publikováno v:
Biophysical Journal. 100:216a
Many cancers overexpress antiapoptotic proteins, which can lead to poor chemotherapy response. This work reports on computational design of druglike small molecules that could potentially facilitate apoptosis by forming complexes with antiapoptotic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430416bd8f41310a986bb2f727c502d4
https://doi.org/10.1016/j.bpj.2010.12.1393
https://doi.org/10.1016/j.bpj.2010.12.1393