Zobrazeno 1 - 10
of 49
pro vyhledávání: '"D.O. Thueson"'
Autor:
Sheila F. Stewart, Clifford D. Wright, Mark A. Ferin, D.O. Thueson, Michael D. Hoffman, Paul J. Kuipers, L. J. Devall, M. C. Conroy, John A. Kennedy
Publikováno v:
Journal of Leukocyte Biology. 55:443-451
The cell activation inhibitor CI-959 [5-methoxy-3-(1-methylethoxy)-N-1H-tetrazol-5-ylbenzo[b]thiophene-2-carboxamide, monosodium salt] was evaluated for its effects on human neutrophil functions. CI-959 inhibited spontaneous migration and chemotaxis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dc1def0baed00ebd8a70c7133a544e
https://doi.org/10.1002/jlb.55.4.443
https://doi.org/10.1002/jlb.55.4.443
Publikováno v:
Agents and Actions. 31:11-15
The allergic mediator release inhibitor CI-949 [5-methoxy-3-(1-methylethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H-indole-2-carboxamide,l-arginine salt] was evaluated for its effect on the activation of human eosinophils, macrophages, and neutrophils by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01daeb557ce76f4b67c9168fb0e21f3
https://doi.org/10.1007/bf02003215
https://doi.org/10.1007/bf02003215
Publikováno v:
Pulmonary Pharmacology. 3:203-208
CI-949 (5-methoxy-3-(1-methyl-ethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H -indole-2-carboxamide) effectively inhibited the release of histamine and the synthesis or release of immunoreactive sulfidopeptide leukotrienes C4-D4 and thromboxane B2 from antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c793b692c47db2d18ba6921193e7836c
https://doi.org/10.1016/0952-0600(90)90018-e
https://doi.org/10.1016/0952-0600(90)90018-e
Publikováno v:
Agents and actions. 36(1-2)
The cell activation inhibitor CI-959 [5-methoxy-3-(1-methyl-ethoxy)-N-1H- tetrazol-5-ylbenzo[b]thiophene-2-carboxamide, monosodium salt] was evaluated for its effect on the activation of human eosinophils, macrophages, and neutrophils by the phagocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd556ecd916cde47433099b638d511f8
https://pubmed.ncbi.nlm.nih.gov/1329446
https://pubmed.ncbi.nlm.nih.gov/1329446
Publikováno v:
Biochemical and biophysical research communications. 167(2)
CI-949 [5-methyl-3-(1-methylethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H- indole-2- carboxamide, L-arginine salt] inhibits human neutrophil activation in response to stimuli which promote calcium mobilization or calcium influx. This report further examines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5650c8a602b4d34759aa0d65c07622e1
https://pubmed.ncbi.nlm.nih.gov/2322255
https://pubmed.ncbi.nlm.nih.gov/2322255
Publikováno v:
International Archives of Allergy and Immunology. 80:427-430
Lung strips from actively sensitized guinea pigs were repeatedly contracted by antigen (ovalbumin, OA) challenge in the presence of the antihistamine (H1) mepyramine. At lower concentrations of OA, hourly challenges gave reproducible and consistent r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c176c55102429584a3dd9f642f5f635
https://doi.org/10.1159/000234093
https://doi.org/10.1159/000234093
Publikováno v:
Biochemical and Biophysical Research Communications. 148:1110-1117
CI-949 [5-methyl-3-(1-methylethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H- indole-2- carboxamide, L-arginine salt] inhibits human neutrophil activation in response to stimuli which promote calcium mobilization or calcium influx. This report further examines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed43db08c61790022dcde9e4c50e607
https://doi.org/10.1016/s0006-291x(87)80247-4
https://doi.org/10.1016/s0006-291x(87)80247-4
Publikováno v:
Journal of Leukocyte Biology. 42:30-35
The allergic mediator release inhibitor 3,7-dimethoxy-4-phenyl-N-1H-tetrazol-5-yl-4H-furo[3,2-b]indole-2-carboxamide, L-arginate (CI-922) is a potent inhibitor of human neutrophil functions in vitro. Over a concentration range from 1 to 100 μmol CI-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3597c8165ba24305de88243e4f4bfd9b
https://doi.org/10.1002/jlb.42.1.30
https://doi.org/10.1002/jlb.42.1.30
Autor:
Y. Nawa, A.Y. Al-Duaij, B. Quatannens, Roberto Guerciolini, Masazumi Terashima, W. Rolfsen, D.D. Sherry, T.D.G. Lee, Shinichi Ohdama, Bryan Smith, Morio Ohtsuka, B.M. Stadler, K. Webster, J. Pepys, R.M. Cook, Harald Darius, Pietro Rambotti, S.-Q. Gu, Shizuo Hasegawa, A. Capron, A.D. Sedgwick, D.L. Scott, C. Mazingue, L.J. Robichaud, Motoichi Tanaka, D.O. Thueson, R. Einarsson, Antonio Frascarelli, Å. Karlsson, J. Wasserman, Roberto Gerli, Svein Kolmannskog, Fausto Grignani, D.A. Willoughby, Shigetoshi Shimada, Allan M. Lefer, Dean Befus, Toshiaki Osawa, J. Imai, A.L. de Weck, Masahiko Tanoue, A. Bengtsson, T. Abe, Hirotsugu Komatsu, R.E. Petty, Fabrizio Spinozzi, Ivano Gernini, R.D. Murdoch, K. Nordlind, J.P. Dessaint, M. Owhashi, C. Auriault, Arthur Malley, F.B. de Brito, A.W. Wheeler, John Bienenstock, Kenji Uetake, J.M. Johannson, D.C. Henderson, Francesco Rondoni, Fergus Shanahan, D.M. Moran, Yasuyuki Yoshizawa, Stephen Davis, J.L. Neyrinck
Publikováno v:
International Archives of Allergy and Immunology. 80:I-V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aa4a87fd2d28075a8edda264d363215
https://doi.org/10.1159/000234077
https://doi.org/10.1159/000234077
Publikováno v:
Biochemical and biophysical research communications. 144(2)
The release of histamine and other inflammatory mediators from human basophils is triggered by numerous stimuli, including chemical, physical and receptor-mediated activators. Several mechanisms of cell activation including protein kinase C activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429fe37eddd15fbb3752a471d5d7522b
https://pubmed.ncbi.nlm.nih.gov/2437919
https://pubmed.ncbi.nlm.nih.gov/2437919