Zobrazeno 1 - 10
of 31
pro vyhledávání: '"D.M.A. Evans"'
Autor:
Radu Crainic, G. C. Schild, M. Stenvik, Morag Ferguson, F. Horaud, Tapani Hovi, D.M.A. Evans, D. I. Magrath, P.D. Minor
Publikováno v:
Journal of General Virology. 67:899-905
Summary Virus isolated from an outbreak of poliomyelitis in Finland has been examined serologically and at the molecular level. The causative agent was an antigenically unusual strain of type 3 poliovirus, which was unrelated to the strains used to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93776341ddb19877cba13539120120aa
https://doi.org/10.1099/0022-1317-67-5-899
https://doi.org/10.1099/0022-1317-67-5-899
Publikováno v:
Nature. 304:459-462
The three serotypes of poliovirus are members of the picornaviradae, a group of viruses which cause a variety of diseases of considerable importance in man and animals. We have previously used antigenic mutants resistant to neutralizing monoclonal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d009a2224951876552e0b265f341f6f
https://doi.org/10.1038/304459a0
https://doi.org/10.1038/304459a0
Autor:
Glynis Dunn, Glyn Stanway, Gareth D. Westrop, D.M.A. Evans, Jeffrey W. Almond, P.D. Minor, Pamela J. Hughes, G. C. Schild
Publikováno v:
Journal of Virology. 57:1187-1190
We investigated the use of infectious cDNA for the production of poliovirus type 1-type 3 recombinants. One such recombinant virus was produced, but a second construct involving the transfer of part of the capsid protein region was not infectious. Ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8788a7ee7454c3df3430d9b30f165e
https://doi.org/10.1128/jvi.57.3.1187-1190.1986
https://doi.org/10.1128/jvi.57.3.1187-1190.1986
Autor:
Glynis Dunn, D.M.A. Evans, Alan J. Cann, Glyn Stanway, P.D. Minor, Gareth D. Westrop, Morag Ferguson, G. C. Schild, Jeffrey W. Almond
Publikováno v:
Annales de l'Institut Pasteur / Virologie. 137:107-125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d749e8a2e32ce596f9c2278dbddb187
https://doi.org/10.1016/s0769-2617(86)80198-8
https://doi.org/10.1016/s0769-2617(86)80198-8
Publikováno v:
Virology. 143(2)
A region of virus capsid protein VP1 located 89–100 amino acids from the N-terminus has been proposed to comprise a major antigenic site involved in the neutralization of poliovirus type 3. Synthetic peptides 10–18 amino acids in length, containi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23eb063dd3832625c82713fbd511ae8
https://pubmed.ncbi.nlm.nih.gov/2414909
https://pubmed.ncbi.nlm.nih.gov/2414909
Autor:
Jeffrey W. Almond, D.M.A. Evans, Alan J. Cann, Glynis Dunn, Jacob V. Maizel, P.D. Minor, Glyn Stanway, Geoffrey C. Schild, Kathleen M. Currey
Publikováno v:
Nature. 314(6011)
Most of the small number of cases of poliomyelitis which occur in countries where Sabin's attenuated poliovirus vaccines are used are temporally associated with administration of vaccine and involve polioviruses of types 2 and 3 (ref. 1). Recent stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92fbdc2e23ae0a748a5f89e71db30e8
https://pubmed.ncbi.nlm.nih.gov/2986004
https://pubmed.ncbi.nlm.nih.gov/2986004
Publikováno v:
The Journal of general virology. 66
Summary The characterization of over 300 mutants, derived from two strains of poliovirus type 3 and selected for resistance to neutralization by monoclonal antibodies, has led to the further definition of the major antigenic site involved in neutrali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e71f6952d160c777a3524ca662f542
https://pubmed.ncbi.nlm.nih.gov/2582084
https://pubmed.ncbi.nlm.nih.gov/2582084
Autor:
Philip D. Minor, Gareth D. Westrop, Glyn Stanway, Morag Ferguson, Geoffrey C. Schild, Alan J. Cann, Jeffrey W. Almond, M. Spitz, D.M.A. Evans
Publikováno v:
Vaccine. 2(3)
This article summarizes recent work on the determinants of antigenicity in poliovirus type 3 and reports on experiments in progress aimed at understanding the molecular basis of attenuation in Sabin's type 3 vaccines. Ways in which this new informati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f2cb017ef799793f858f2d25cc7bb1
https://pubmed.ncbi.nlm.nih.gov/6085198
https://pubmed.ncbi.nlm.nih.gov/6085198
Publikováno v:
The Journal of general virology. 67
The antigenic sites recognized by monoclonal antibodies with neutralizing activity for the Sabin vaccine strains of poliovirus of serotypes 1, 2 and 3 have been studied by the isolation and characterization of mutants resistant to neutralization by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e382f837c5f159edd6a0e07b20daa4e
https://pubmed.ncbi.nlm.nih.gov/2425046
https://pubmed.ncbi.nlm.nih.gov/2425046