Výsledky vyhledávání

In-depth cell-free DNA sequencing reveals genomic landscape of Hodgkin's lymphoma and facilitates ultrasensitive residual disease detection

Publikováno v: Sobesky, S, Mammadova, L, Cirillo, M, Drees, E E E, Mattlener, J, Dörr, H, Altmüller, J, Shi, Z, Bröckelmann, P J, Weiss, J, Kreissl, S, Sasse, S, Ullrich, R T, Reinke, S, Klapper, W, Gerhard-Hartmann, E, Rosenwald, A, Roemer, M G M, Nürnberg, P, Hagenbeek, A, Zijlstra, J M, Pegtel, D M, Engert, A, Borchmann, P, von Tresckow, B & Borchmann, S 2021, ' In-depth cell-free DNA sequencing reveals genomic landscape of Hodgkin's lymphoma and facilitates ultrasensitive residual disease detection ', Med, vol. 2, no. 10, pp. 1171-1193.e11 . https://doi.org/10.1016/j.medj.2021.09.002
Med (New York, N.Y.), 2(10), 1171-1193.e11. Cell Press
Med, 2(10), 1171-1193.e11. Cell Press

Summary Background Individualization of treatment in Hodgkin’s lymphoma is necessary to improve cure rates and reduce treatment side effects. Currently, it is hindered by a lack of genomic characterization and sensitive molecular response assessmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6f4840b2350430e78a3fc30979b535
https://research.vumc.nl/en/publications/8da398e7-192c-412f-b985-e71916868ffd

Zobrazit plný text záznamu

Vesicle-bound EBV-BART13-3p miRNA in circulation distinguishes nasopharyngeal from other head and neck cancer and asymptomatic EBV-infections

Autor: Chantal Scheepbouwer, Marlinda Adham, Lisa Beckers, Jan R.T. van Weering, Sandra A. W. M. Verkuijlen, Putri W. Novianti, Jaap M. Middeldorp, Octavia Ramayanti, Danijela Koppers-Lalic, D.M. Pegtel, Debora Martorelli, Branislav Misovic

Publikováno v: Ramayanti, O, Verkuijlen, S A W M, Novianti, P, Scheepbouwer, C, Misovic, B, Koppers-Lalic, D, van Weering, J, Beckers, L, Adham, M, Martorelli, D, Middeldorp, J M & Pegtel, D M 2019, ' Vesicle-bound EBV-BART13-3p miRNA in circulation distinguishes nasopharyngeal from other head and neck cancer and asymptomatic EBV-infections ', International Journal of Cancer, vol. 144, no. 10, pp. 2555-2566 . https://doi.org/10.1002/ijc.31967
International Journal of Cancer, 144(10), 2555-2566. International Union Against Cancer
International Journal of Cancer, 144(10), 2555-2566. Wiley-Liss Inc.
International Journal of Cancer

Cell‐free microRNA (miRNA) in biofluids released by tumors in either protein or vesicle‐bound form, represent promising minimally‐invasive cancer biomarkers. However, a highly abundant non‐tumor background in human plasma and serum complicate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5478b5e61a4b9c9f0177cfc256c546e7
https://doi.org/10.1002/ijc.31967

Zobrazit plný text záznamu

Unbiased and UMI-informed sequencing of cell-free miRNAs at single-nucleotide resolution

Autor: Ernesto Aparicio-Puerta, Bosch L, Michael Hackenberg, Cristina Gómez-Martín, Bradley E, Esther E.E. Drees, Chantal Scheepbouwer, D.M. Pegtel, van Eijndhoven M, José María Medina

Terminal nucleotidyl transferases are enzymes that add non-templated nucleotides to RNA molecules. In the case of microRNAs, this process was shown to be functionally relevant for their maturation process and generation of isomiRs with non-canonical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ea2845cc3ae7806ac887d61989ad847
https://doi.org/10.1101/2021.05.04.442244

Zobrazit plný text záznamu

Exhaustive circulating tumor DNA sequencing reveals the genomic landscape of Hodgkin lymphoma and facilitates ultrasensitive detection of minimal residual disease

Individualizing treatment is key to improve outcome and reduce long-term side-effects in any cancer. In Hodgkin lymphoma (HL), individualization of treatment is hindered by a lack of genomic characterization and technology for sensitive, molecular re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49dbb6c927869800ded0fa3464fc4b42
https://doi.org/10.1101/2021.03.16.21253679

Zobrazit plný text záznamu

Exosomes take (germinal) center stage

Autor: Jennifer Perez-Boza, D.M. Pegtel

Publikováno v: Pérez-Boza, J & Pegtel, D M 2020, ' Exosomes take (germinal) center stage ', EMBO Reports, vol. 21, no. 4, e50190 . https://doi.org/10.15252/embr.202050190
EMBO Rep
EMBO Reports, 21(4):e50190. Wiley-Blackwell

Intercellular communication orchestrates effective immune responses against disease-causing agents. Extracellular vesicles (EVs) are potent mediators of cell-cell communication. EVs carry bioactive molecules, including microRNAs, which modulate gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02731b29582e20a0e2fcf5b8b9cad47f
https://research.vumc.nl/en/publications/364cb377-4629-4597-bf92-b97925da5ca4

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání