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Akademický článek

A voxel-wise assessment of growth differences in infants developing autism spectrum disorder

Autor: A. Cárdenas-de-la-Parra, J.D. Lewis, V.S. Fonov, K.N. Botteron, R.C. McKinstry, G. Gerig, J.R. Pruett, Jr., S.R. Dager, J.T. Elison, M.A. Styner, A.C. Evans, J. Piven, D.L Collins

Publikováno v: NeuroImage: Clinical, Vol 29, Iss , Pp 102551- (2021)

Autism Spectrum Disorder (ASD) is a phenotypically and etiologically heterogeneous developmental disorder typically diagnosed around 4 years of age. The development of biomarkers to help in earlier, presymptomatic diagnosis could facilitate earlier i

Externí odkaz: https://doaj.org/article/f9439540c087406ca48ba106813670e9

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Akademický článek

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Akademický článek

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Akademický článek

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Akademický článek

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White matter hyperintensities may be an early marker for age-related cognitive decline

Autor: Mahsa Dadar, C. Morrison, Sylvia Villeneuve, D.L. Collins

BackgroundResearch suggests that cerebral small vessel disease (CSVD), amyloid, and pTau contribute to age-related cognitive decline. It remains unknown how these factors relate to one another, nor how they jointly contribute to cognitive decline in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b197cc73c61462ec3761538a2dd27359
https://doi.org/10.1101/2021.09.23.461560

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Diffusely abnormal white matter converts to T2 lesion volume in the absence of acute inflammation

Autor: Sridar Narayanan, Douglas L. Arnold, M. Dadar, D.L. Collins, Josefina Maranzano, Sawsan Mahmoud

Diffusely abnormal white matter (DAWM), characterised by biochemical changes of myelin in the absence of frank demyelination, has been associated with clinical progression in secondary progressive MS (SPMS). However, little is known about changes of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::325a289409a7cca7c8d79ed0957d4422
https://doi.org/10.1101/2021.08.09.455717

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An accurate registration of the BigBrain dataset with the MNI PD25 and ICBM152 atlases

Autor: Yanyu Xiao, Jonathan C. Lau, Ali R. Khan, Taylor Anderson, Terry M. Peters, D.L. Collins, Jordan DeKraker

Publikováno v: Scientific Data, Vol 6, Iss 1, Pp 1-9 (2019)
Brain and Mind Institute Researchers' Publications
Medical Biophysics Publications
Scientific Data

Brain atlases that encompass detailed anatomical or physiological features are instrumental in the research and surgical planning of various neurological conditions. Magnetic resonance imaging (MRI) has played important roles in neuro-image analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1770cdeab1cb582b7fed98caafa8111
http://link.springer.com/article/10.1038/s41597-019-0217-0

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HIV infection and cerebral small vessel disease are independently associated with brain atrophy and cognitive impairment

Autor: D.L. Collins, Mahsa Dadar, Alexandre Bonnet, Josefina Maranzano, Ryan Sanford, Beau M. Ances, Nancy E. Mayo, Lesley K. Fellows, Susan C. Scott, Jeremy F. Strain

Publikováno v: AIDS

OBJECTIVE: The objective of this study is to investigate whether cerebral small vessel disease (CSVD) is more common in virologically suppressed HIV-positive participants compared with HIV-negative controls and examine the potential synergistic effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfc56563631b29cf1677930e74236aa
https://doi.org/10.1097/qad.0000000000002193

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White Matter Hyperintensities, Grey Matter Atrophy, and Cognitive Decline in Neurodegenerative Diseases

Autor: Mahsa Dadar, D.L. Collins, Ana L. Manera

IntroductionWhite matter hyperintensities (WMHs) as seen on T2w and FLAIR scans represent small-vessel disease related changes in the brain. WMHs are associated with cognitive decline in the normal aging population in general and more specifically in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14b5e2d774b9bc00d96a20add90d6281
https://doi.org/10.1101/2021.04.06.438619

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