Zobrazeno 1 - 10
of 66
pro vyhledávání: '"D.K. Vaughan"'
Autor:
Tyesha N. Burks, Florian Lang, Benjamin Lin, Ruth Marx, Christophe Hourdé, Martin Steinberger, Brian M. Lin, Michael Föller, Leslie A. Leinwand, Erika Finanger Hedderick, Tom G. Marr, Ivan Hernandez-Diaz, Silke Vogelsang, Diego Alvarez de la Rosa, Heinrich Brinkmeier, D.K. Vaughan, Daniel C. Files, Ronald D. Cohn, Rebeca Mejias, Dietmar Kuhl, Eva Andres-Mateos, Arshia Soleimani, Jessica L. Simmers
Publikováno v:
EMBO Molecular Medicine
Maintaining skeletal muscle mass is essential for general health and prevention of disease progression in various neuromuscular conditions. Currently, no treatments are available to prevent progressive loss of muscle mass in any of these conditions.
Autor:
Daniel T. Organisciak, D.K. Vaughan
Publikováno v:
Progress in Retinal and Eye Research. 29:113-134
By its action on rhodopsin, light triggers the well-known visual transduction cascade, but can also induce cell damage and death through phototoxic mechanisms -- a comprehensive understanding of which is still elusive despite more than 40 years of re
Publikováno v:
Photochemistry and Photobiology. 75:547-553
This study investigated a possible circadian rhythm of light damage susceptibility in photoreceptors of both cyclic light-reared and dark-reared rats. A single exposure to intense green light was administered, beginning either in the early light peri
Autor:
D.K. Vaughan, B.A. Nagel, Steven J. Fliesler, M.J. Richards, Neal S. Peachey, Erin C Jenewein
The Smith-Lemli-Opitz syndrome (SLOS) is the first-described in a growing family of hereditary defects in cholesterol biosynthesis, and presents with a spectrum of serious abnormalities, including multiple dysmorphologies, failure to thrive, cognitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83037b7186a07583c28b8bfd9ccaed3e
https://europepmc.org/articles/PMC2072818/
https://europepmc.org/articles/PMC2072818/
Autor:
D.K. Vaughan, Aaron R. Gruber, Michelle L. Michalski, Jeffery Richard Seidling, Sarah Schlink
Publikováno v:
Lab animal. 35(4)
Researchers use the 13-lined ground squirrel for studies of hibernation biochemistry and physiology, as well as for modeling a variety of potential biomedical applications of hibernation physiology. It is currently necessary to capture research speci
Publikováno v:
Experimental eye research. 82(3)
Potentiation of retinal degeneration by intense light exposure, and its amelioration by an antioxidant, were studied in a rat model of Smith-Lemli-Opitz syndrome (SLOS), in comparison with normal (control) Sprague-Dawley rats. The SLOS model is creat
Publikováno v:
Archives of ophthalmology (Chicago, Ill. : 1960). 122(8)
To assess the electrophysiologic, histologic, and biochemical features of an animal model of Smith-Lemli-Opitz syndrome (SLOS).Sprague-Dawley rats were treated with AY9944, a selective inhibitor of 3beta-hydroxysterol-Delta(7)-reductase (the affected
Publikováno v:
Investigative ophthalmologyvisual science. 44(2)
PURPOSE. To determine relative susceptibility to, and regional variation of, light-induced retinal damage in two rhodopsinmutant rat models of retinitis pigmentosa, using slow- and fast-degenerating lines. METHODS. Transgenic S334ter (lines 4 and 9)
Autor:
D.K. Vaughan
Publikováno v:
IPCC 91 Proceedings The Engineered Communication.
Although technical writing programs have grown in size and number in academic institutions, analysis and discussion of the specialized writing tasks and communications needs of the engineer have not developed accordingly. The emphasis in traditional
Autor:
D.K. Vaughan, J. Isenberg
Publikováno v:
Nuclear Engineering and Design. 77:229-250
The SIMQUAKE series of field tests on model containment structures provides a data base which may be used to validate analytic models of soil-structure interaction (SSI). In addition, the test produced significant evidence of nonlinear rocking respon