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pro vyhledávání: '"D.J.A. Crommelin"'
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Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1328:261-272
The present paper reports on the results of a systematic study on liposome variables potentially affecting lymphatic disposition and biodistribution of liposomes after sc injection. Liposomal size was found to be the most important factor influencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0cc515550c9a178587c4d45fec1e66
https://doi.org/10.1016/s0005-2736(97)00122-3
https://doi.org/10.1016/s0005-2736(97)00122-3
Publikováno v:
International Journal of Pharmaceutics. 129:191-202
In this study a procedure is described for preparation and storage of liposomes containing glu-plasminogen (Plg) — as a homing device — coupled to the outside of the liposome bilayer and physically entrapped tissue-type Plasminogen Activator (t-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec5337b9942248154fdea4001f2dd42
https://doi.org/10.1016/0378-5173(95)04325-x
https://doi.org/10.1016/0378-5173(95)04325-x
Autor:
Nicolaas J. Zuidam, D.J.A. Crommelin
Publikováno v:
International Journal of Pharmaceutics. 126:209-217
Hydrolysis of liposomal dipalmitoylphosphatidylcholine (DPPC) at pH 4.0 or 10.5 and at 30°C resulted in the formation of free palmitic acid (PA), 1- or 2-palmitoyl-sn-glycerol-phosphoryl choline (LPC) and glycerophospho compounds. As determined by d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ac9d334c5583230022267be44d31a7
https://doi.org/10.1016/0378-5173(95)04129-x
https://doi.org/10.1016/0378-5173(95)04129-x
Publikováno v:
Journal of Controlled Release. 29:317-327
Tumour-associated antigens (TAA) that are expressed on tumour cells can induce resistance to tumour transplants in immunized syngeneic hosts. In this report three issues related to tumour vaccines are discussed. (1) Solubilization of TAA from tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2694794949c053afd4ef3227607d8743
https://doi.org/10.1016/0168-3659(94)90077-9
https://doi.org/10.1016/0168-3659(94)90077-9
Publikováno v:
Fibrinolysis. 8:138-141
In this study the importance of the absence of c-amino-caproic acid (EACA) for the thiol-introduction into glu-plasminogen (glu-Plg) with the SATA-reaction (SATA=N-Succinimidyl S-acetylthioacetate) was demonstrated. It was shown that under the chosen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44cd34e7701eb9dc2fed5c5bee5c715f
https://doi.org/10.1016/0268-9499(94)90276-3
https://doi.org/10.1016/0268-9499(94)90276-3
Publikováno v:
Journal of Liposome Research. 4:641-666
Ovarian cancer is the leading cause of death in women with a gynecologic malignancy. The main reason for the high mortality is the late occurrence of symptoms, resulting in an advanced diseased state at the time of diagnosis. Since ovarian cancer rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::222532d76b68df17ca09aaece4bda4aa
https://doi.org/10.3109/08982109409037064
https://doi.org/10.3109/08982109409037064
Autor:
G. Cevc, Gert Storm, D.J.A. Crommelin, G. Blume, Irma A. J. M. Bakker-Woudenberg, M. H. Vingerhoeds, Hidde J. Haisma
Publikováno v:
Journal of Liposome Research. 3:551-562
Delivery of the drug at a specific site (drug targeting) or controlled and prolonged release of the liposome-bound drug are the two major considerations for adding liposomes to the existing arsenal of drug delivery systems. In particular the concept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dee05c604764affea5a32443f5e29c9b
https://doi.org/10.3109/08982109309150738
https://doi.org/10.3109/08982109309150738
Publikováno v:
Journal of Controlled Release. 20:47-54
Chloroquine (CQ) levels in blood, heart, liver, spleen and kidney as a function of time were determined after intramuscular (i.m.) injection of increasing amounts (0.64,1.32,1.98,2.63 and 3.30 mg) of liposome-encapsulated chloroquine (lip-CQ) to mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13655a67c0ac3dc7f89c0101fa822567
https://doi.org/10.1016/0168-3659(92)90138-h
https://doi.org/10.1016/0168-3659(92)90138-h