Zobrazeno 1 - 10
of 162
pro vyhledávání: '"D.G. Miles"'
Background: Although red cell distribution width (RDW) is associated with increased cardiovascular mortality, the relationship between an elevated RDW and cardiovascular mortality among various ASCVD risk groups is unknown. Methods: We utilized the N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::424ef0ed29a251f45e58aac866cd2c84
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3100381
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3100381
Autor:
Richard Eberle, C. Landis, Christopher C. L. Chase, D.G. Miles, Jean M. d'Offay, Julia F. Ridpath, John D. Neill, Jeremiah T. Saliki, Anthony W. Confer, Travis Clement, Lurinda J. Burge, Robert W. Fulton, Mark E. Payton, R. A. Smith
Publikováno v:
Vaccine
This study investigated viruses in bovine respiratory disease (BRD) cases in feedlots, including bovine herpesvirus-1 (BoHV-1), bovine viral diarrhea virus (BVDV), bovine respiratory syncytial virus (BRSV), bovine coronaviruses (BoCV) and parainfluen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee59412ba8c507a7e1813a142cd779f5
https://doi.org/10.1016/j.vaccine.2016.04.020
https://doi.org/10.1016/j.vaccine.2016.04.020
Autor:
Xiaoyong Yang, Jerrold M. Olefsky, Robert H. Michell, Seth J. Field, W. Venus So, Joyce C. Havstad, Jeffrey E. Kudlow, Pat P. Ongusaha, Philip D.G. Miles, Ronald M. Evans, Fengxue Zhang
Publikováno v:
Nature. 451:964-969
Glucose flux through the hexosamine biosynthetic pathway leads to the post-translational modification of cytoplasmic and nuclear proteins by O-linked beta-N-acetylglucosamine (O-GlcNAc). This tandem system serves as a nutrient sensor to couple system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8b865479422f4593ef55dbed0a21e5
https://doi.org/10.1038/nature06668
https://doi.org/10.1038/nature06668
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 293:E70-E74
Ataxia telangiectasia (A-T) is an autosomal recessive disease caused by mutations in the A-T mutated (ATM) gene. The gene encodes a serine/threonine kinase with important roles in the cellular response to DNA damage, including the activation of cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fcc67de2c3220c2e6c0397247a0934
https://doi.org/10.1152/ajpendo.00259.2006
https://doi.org/10.1152/ajpendo.00259.2006
Autor:
Hiroaki Satoh, M. T. Audrey Nguyen, Jerrold M. Olefsky, Philip D.G. Miles, Isao Usui, Takeshi Imamura
Publikováno v:
Journal of Clinical Investigation. 114:224-231
We investigated the chronic in vivo effect of resistin on insulin sensitivity and glucose metabolism by overexpressing resistin protein in male Wistar rats using intravenous administration of an adenovirus encoding mouse resistin. After 7 days of ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd057baff9bccd1def198ed4e106df1
https://doi.org/10.1172/jci20785
https://doi.org/10.1172/jci20785
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 284:E618-E626
Peroxisome proliferator-activated receptor-γ (PPARγ) is the target receptor for thiazolidinedione (TZD) compounds, which are a class of insulin-sensitizing drugs used in the treatment of type 2 diabetes. Paradoxically, however, mice deficient in PP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf269d6d7eb0448d081f7ec4febdd8d
https://doi.org/10.1152/ajpendo.00312.2002
https://doi.org/10.1152/ajpendo.00312.2002
Autor:
Christine Ladd, Todd R. Golub, Harvey F. Lodish, Kenneth N. Ross, Hong Ruan, Jerrold M. Olefsky, Philip D.G. Miles
Publikováno v:
Diabetes. 51:3176-3188
Despite extensive studies implicating tumor necrosis factor (TNF)-alpha as a contributing cause of insulin resistance, the mechanism(s) by which TNF-alpha alters energy metabolism in vivo and the tissue specificity of TNF-alpha action are unclear. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf2c77b22ca681c2e7e40aab0b58c521
https://doi.org/10.2337/diabetes.51.11.3176
https://doi.org/10.2337/diabetes.51.11.3176
Publikováno v:
Diabetes. 50:139-142
The infusion of glucosamine causes insulin resistance, presumably by entering the hexosamine biosynthetic pathway; it has been proposed that this pathway plays a role in hyperglycemia-induced insulin resistance. This study was undertaken to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e453ff2845ca84e28a2d0a3dd4b20901
https://doi.org/10.2337/diabetes.50.1.139
https://doi.org/10.2337/diabetes.50.1.139
Publikováno v:
Diabetes. 47:395-400
Hyperglycemia can lead directly to a secondary state of insulin resistance or can worsen a preexisting insulin-resistant state. Troglitazone is an orally active hypoglycemic agent that has been shown to ameliorate insulin resistance and hyperinsuline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25394ee184579c65302456d13e9b4483
https://doi.org/10.2337/diabetes.47.3.395
https://doi.org/10.2337/diabetes.47.3.395
Autor:
Karim Rafaat, Katsuya Higo, Jerrold M. Olefsky, Oreste M Romeo, Philip D.G. Miles, Aaron Cohen
Publikováno v:
Diabetes. 46:1678-1683
Tumor necrosis factor (TNF)-alpha may play a role in the insulin resistance of obesity and NIDDM. Troglitazone is a new orally active hypoglycemic agent that has been shown to ameliorate insulin resistance and hyperinsulinemia in both diabetic animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19997bc8e57a5042aebe05db2e2f897e
https://doi.org/10.2337/diab.46.11.1678
https://doi.org/10.2337/diab.46.11.1678